6HK4-N-A

PDB Title CRYSTAL STRUCTURE OF GSK-3B IN COMPLEX WITH PYRAZINE INHIBITOR C22
Resolution (Å) 2.500
Classification TRANSFERASE

Protein

Description Glycogen synthase kinase-3 beta
Organism Homo sapiens
Chain A
Length 355
Binding Area (Å2) 285.04
Molecular Weight -
Aromaticity 0.10
Instability -
Isoelectric Point 8.87
Sequence SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSXICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIXXXXX

Peptide

Description GLY-SER-HIS-GLY-HIS-HIS-HIS-HIS-HIS
Organism Homo sapiens
Chain N
Length 9
Binding Area (Å2) 352.50
Hydrophobic (% a.a.)
22%
Molecular Weight 1042.03
Aromaticity 0.00
Instability -2.63
Isoelectric Point 7.21
Sequence GSHGHHHHH

Clustering Classification

Sequence cluster S 340
Contact cluster C348
Interface cluster I513

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S340) 		Contact cluster
(C348) 		Interface cluster
(I513)
6hk3-N-A
2v5f-X-A
3mpj-Y-B
3ngy-E-D
3rof-B-A
5fpx-F-B
5h0u-B-A