5MXO-P-A

PDB Title CRYSTAL STRUCTURE OF 14-3-3SIGMA AND A P53 C-TERMINAL 12-MER SYNTHETIC PHOSPHOPEPTIDE STABILIZED BY FUSICOCCIN-A
Resolution (Å) 1.200
Classification ANTITUMOR PROTEIN

Protein

Description 14-3-3 protein sigma
Organism Homo sapiens
Chain A
Length 226
Binding Area (Å2) 214.20
Molecular Weight -
Aromaticity 0.07
Instability -
Isoelectric Point 5.20
Sequence GAMGSMERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWRVLSSIEQKSNGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFYLKMKGDYYRYLAEVATDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFHYEIANSPEEAISLAKTTFDEAMADLHTLSKDSTLIMQLLRDNLTLWTXXX

Peptide

Description p53 C-terminal 12 amino acids
Organism synthetic construct
Chain P
Length 2
Binding Area (Å2) 300.32
Hydrophobic (% a.a.)
50%
Molecular Weight 293.36
Aromaticity 0.50
Instability -70.15
Isoelectric Point 8.75
Sequence FK

Clustering Classification

Sequence cluster S 1609
Contact cluster C12
Interface cluster I1434

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S1609) 		Contact cluster
(C12) 		Interface cluster
(I1434)
3e6y-C-A
6bcy-C-A
6qzr-U-H
3e6y-D-B
6bcy-G-E
6tjm-B-A
3lw1-P-A
6hhp-B-A
6tl3-B-A
4gnt-B-A
6hkb-B-A
4jc3-B-A
6hkf-B-A
4jdd-B-A
6hmt-B-A
4n7g-B-A
6hmu-B-A
4qli-B-A
6qdr-B-A
5ewz-C-A
6qds-B-A
1o9d-P-A
5exa-C-B
6qdt-B-A
2o02-P-A
5exa-D-A
6qzr-R-F
2o02-Q-B
5f74-B-A
6qzr-J-E
2v7d-P-A
5mhc-P-A
6qzr-M-B
2v7d-Q-B
5n10-F-B
6qzr-N-A
2v7d-R-C
5xy9-C-A
6qzr-O-C
2v7d-S-D
5xy9-D-B
6qzr-T-G