5E3A-B-A

PDB Title STRUCTURE OF HUMAN DPP3 IN COMPLEX WITH OPIOID PEPTIDE LEU-ENKEPHALIN
Resolution (Å) 2.050
Classification HYDROLASE

Protein

Description Dipeptidyl peptidase 3
Organism Homo sapiens
Chain A
Length 729
Binding Area (Å2) 553.47
Molecular Weight -
Aromaticity 0.11
Instability -
Isoelectric Point 5.06
Sequence ADTQYILPNDIGVSSLDSREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGCGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHALLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRCGETWDSKFSTIASSYEECRAESVGLYLSLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPESFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFWXXXX

Peptide

Description Leu-enkephalin
Organism Homo sapiens
Chain B
Length 5
Binding Area (Å2) 704.23
Hydrophobic (% a.a.)
80%
Molecular Weight 555.62
Aromaticity 0.40
Instability 15.70
Isoelectric Point 5.52
Sequence YGGFL

Clustering Classification

Sequence cluster S 672
Contact cluster C173
Interface cluster I171

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S672) 		Contact cluster
(C173) 		Interface cluster
(I171)
5e33-B-A
3t6b-C-A
3t6b-D-B
5e2q-B-A