4MDD-C-A

PDB Title CRYSTAL STRUCTURE OF THE GLUCOCORTICOID RECEPTOR BOUND TO A NON- STEROIDAL ANTAGONIST REVEALS REPOSITIONING AND PARTIAL DISORDERING OF ACTIVATION FUNCTION HELIX 12
Resolution (Å) 2.400
Classification PROTEIN BINDING

Protein

Description Glucocorticoid receptor
Organism Homo sapiens
Chain A
Length 248
Binding Area (Å2) 526.59
Molecular Weight -
Aromaticity 0.10
Instability -
Isoelectric Point 6.62
Sequence PTLVSALETIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQALFDAIRMTYIKELGKAIVKREGNSSQNSQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQX

Peptide

Description Nuclear receptor corepressor 1
Organism Homo sapiens
Chain C
Length 13
Binding Area (Å2) 571.98
Hydrophobic (% a.a.)
69%
Molecular Weight 1428.74
Aromaticity 0.00
Instability 24.05
Isoelectric Point 6.07
Sequence LGLEDIIRKALMG

Clustering Classification

Sequence cluster S 198
Contact cluster C1251
Interface cluster I1258

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S198) 		Contact cluster
(C1251) 		Interface cluster
(I1258)
6oni-D-B
6pdz-C-B
6pdz-D-A
3q5u-B-A
4oar-B-A
5x8q-D-C
5x8q-H-G
6ivx-B-A
6ivx-F-E
6ivx-H-G