3PSL-C-A

PDB Title FINE-TUNING THE STIMULATION OF MLL1 METHYLTRANSFERASE ACTIVITY BY A HISTONE H3 BASED PEPTIDE MIMETIC
Resolution (Å) 1.700
Classification TRANSCRIPTION/TRANSCRIPTION INHIBITOR

Protein

Description WD repeat-containing protein 5
Organism Homo sapiens
Chain A
Length 298
Binding Area (Å2) 281.04
Molecular Weight 32776.99
Aromaticity 0.10
Instability 26.31
Isoelectric Point 8.87
Sequence KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC

Peptide

Description N-alpha acetylated form of histone H3
Organism -
Chain C
Length 4
Binding Area (Å2) 494.22
Hydrophobic (% a.a.)
25%
Molecular Weight 474.56
Aromaticity 0.00
Instability 7.50
Isoelectric Point 11.00
Sequence ARTK

Clustering Classification

Sequence cluster S 537
Contact cluster C20
Interface cluster I18

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S537) 		Contact cluster
(C20) 		Interface cluster
(I18)
3uvm-B-A
4esg-C-B
3uvn-B-A
4esg-D-A
3uvn-D-C
4ewr-C-A
3uvo-B-A
4o45-B-A
4cy1-C-B
4cy1-D-A
4cy2-D-A
2co0-B-A
4cy3-D-A
2co0-D-C
4cy5-D-A
2h9m-B-A
4erq-D-A
3eg6-C-A
4erq-E-B
3emh-B-A
4ery-D-A
3p4f-C-A
4erz-D-C
4erz-E-A
3uvk-B-A
4erz-F-B
3uvl-B-A
4es0-C-A
3uef-D-C