3MVH-B-A

PDB Title CRYSTAL STRUCTURE OF AKT-1-INHIBITOR COMPLEXES
Resolution (Å) 2.010
Classification TRANSFERASE

Protein

Description v-akt murine thymoma viral oncogene homolog 1 (AKT1)
Organism Homo sapiens
Chain A
Length 313
Binding Area (Å2) 549.79
Molecular Weight -
Aromaticity 0.12
Instability -
Isoelectric Point 6.25
Sequence VTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQRPHFPQFDYSAXX

Peptide

Description GSK3-beta peptide
Organism -
Chain B
Length 10
Binding Area (Å2) 677.81
Hydrophobic (% a.a.)
40%
Molecular Weight 1121.20
Aromaticity 0.10
Instability 20.72
Isoelectric Point 9.60
Sequence GRPRTTSFAE

Clustering Classification

Sequence cluster S 155
Contact cluster C3
Interface cluster I43

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S155) 		Contact cluster
(C3) 		Interface cluster
(I43)
3cqu-C-A
1o6k-C-A
2jdo-C-A
3cqw-C-A
1o6l-C-A
2jdr-C-A
2uw9-C-A
3e87-D-B
3e88-D-B
3qkk-C-A
3qkl-C-A
2x39-C-A
3mv5-C-A
2uw6-I-A
3amb-B-A
3e8e-Q-P
3nx8-B-A
3zo2-I-A
4dh3-I-A
4xw4-B-A
5m6v-B-A
5n39-B-A
6e99-B-A
1l3r-I-E
1xh8-B-A
2gnj-I-A
2uw7-I-A
3oog-B-A
3zo3-I-A
4dh5-I-A
4xw5-B-A
5m6y-B-A
5n3a-B-A
6eh2-B-A
1xh9-B-A
2gu8-C-A
2uw8-I-A
3ow3-B-A
3zo4-I-A
4dh7-I-A
4xw6-B-A
5m71-B-A
5n3b-B-A
6eh3-C-A
1xha-B-A
3dnd-I-A
3fjq-I-E
3owp-B-A
4axa-I-A
4dh8-I-A
4yxr-I-A
5m75-B-A
5n3c-B-A
6emd-D-A
1q61-I-A
1ydr-I-E
2jds-I-A
2uzt-B-A
3dne-I-A
3iec-E-A
3oxt-B-A
4c33-I-A
4iac-S-A
4yxs-I-A
5mhi-B-A
5n3d-B-A
6ert-D-A
1q62-I-A
1yds-I-E
2jdt-I-A
2uzu-I-E
3iec-G-C
3p0m-B-A
4c34-I-A
4ie9-I-A
4z83-I-E
5n1d-B-A
5n3e-B-A
6erv-B-A
1q8t-B-A
1ydt-I-E
2jdv-I-A
2uzv-2-A
3iec-H-D
3poo-B-A
4c35-I-A
4o22-S-A
4z84-I-A
5n1e-B-A
5n3f-B-A
6erw-D-A
1q8u-B-A
2c1a-I-A
2oh0-I-E
2uzw-I-E
3e8c-G-A
3kkv-I-A
3qal-I-E
4c37-I-A
4uj1-B-A
5bx6-B-A
5n1l-B-A
5n7p-B-A
6f14-B-A
1q8w-B-A
2c1b-I-A
2ojf-I-E
2vnw-I-A
3e8c-H-B
3l9l-C-A
3qam-I-E
4c38-I-A
4uj2-B-A
5fg8-B-A
5n1m-B-A
5n7u-B-A
6frx-B-A
1rdq-I-E
2erz-I-E
2uvx-I-A
2vny-I-A
3e8c-J-D
3l9l-D-B
4dc2-Z-A
4uj9-B-A
5h9b-B-A
5n1n-B-A
5o0e-C-A
6i2d-D-A
1stc-I-E
2f7e-I-E
2uvy-I-A
2vo0-I-A
3e8c-K-E
3l9m-C-A
4dfx-I-E
4uja-B-A
5hu3-B-A
5n1o-B-A
5otg-D-A
6mm5-C-E
1apm-I-E
1sve-B-A
2f7x-I-E
2uvz-I-A
2vo3-I-A
3e8c-L-F
3l9m-D-B
3vqh-B-A
4dfz-I-E
4wb5-I-A
5lct-B-A
5n23-B-A
5ous-B-A
6qj7-B-A
1atp-I-E
1svg-B-A
2gfc-I-A
2uw0-I-A
2vo6-I-A
3e8e-G-A
3l9n-C-A
3x2u-S-A
4dg0-I-E
4wb6-I-A
5lcu-B-A
5n32-B-A
5uzk-I-A
1cdk-I-A
1svh-B-A
2gnf-I-A
2uw3-I-A
2vo7-I-A
3e8e-F-E
3x2v-S-A
4dg2-I-E
4wb6-J-B
5li1-B-A
5n33-B-A
5vhb-B-A
1cdk-J-B
1xh4-B-A
2gng-I-A
2uw4-I-A
3e8e-J-I
3x2w-S-A
4dg3-A-E
4wb8-I-A
5m0c-B-A
5n36-B-A
5vi9-B-A
1fmo-I-E
1xh6-B-A
2gnh-I-A
2uw5-I-A
3ama-B-A
3e8e-N-L
3zo1-I-A
4dh1-I-A
4wih-B-A
5m0l-B-A
5n37-B-A
5vib-B-A
1jbp-S-E
1xh7-B-A
2gni-I-A
3eqs-B-A
3eqy-D-B
3lnz-J-I
3lnz-L-K