2CV3-B-A

PDB Title CRYSTAL STRUCTURE OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH A MACROCLYCLIC PEPTIDE INHIBITOR
Resolution (Å) 1.900
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description Elastase 1
Organism Sus scrofa
Chain A
Length 240
Binding Area (Å2) 553.02
Molecular Weight 25907.80
Aromaticity 0.09
Instability 24.64
Isoelectric Point 8.44
Sequence VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEHNLNQNDGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLAQSVTLNSYVQLGVLPRAGTILANNSPCYITGWGLTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN

Peptide

Description Inhibitor FR901451
Organism Flexibacter sp.
Chain B
Length 11
Binding Area (Å2) 742.81
Hydrophobic (% a.a.)
27%
Molecular Weight 1324.39
Aromaticity 0.18
Instability 36.39
Isoelectric Point 4.17
Sequence TTLKFPSDWDD

Clustering Classification

Sequence cluster S 980
Contact cluster C38
Interface cluster I36

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S980) 		Contact cluster
(C38) 		Interface cluster
(I36)
2bda-P-A
2h1u-P-A
1gvk-A-B
1h9l-A-B
1hax-A-B
1nes-J-E
1qix-A-B
2bb4-P-A
2bd2-P-A
2bd3-P-A
2bd4-P-A
2bd5-P-A
2bd7-P-A
2bd8-P-A
1fle-I-E
1mcv-I-A
1nes-I-E