1YCQ-B-A

PDB Title XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53
Resolution (Å) 2.300
Classification COMPLEX (ONCOGENE PROTEIN/PEPTIDE)

Protein

Description MDM2
Organism Xenopus laevis
Chain A
Length 88
Binding Area (Å2) 461.31
Molecular Weight 10061.60
Aromaticity 0.08
Instability 41.94
Isoelectric Point 8.16
Sequence EKLVQPTPLLLSLLKSAGAQKETFTMKEVIYHLGQYIMAKQLYDEKQQHIVHCSNDPLGELFGVQEFSVKEPRRLYAMISRNLVSANV

Peptide

Description P53
Organism Homo sapiens
Chain B
Length 11
Binding Area (Å2) 558.87
Hydrophobic (% a.a.)
45%
Molecular Weight 1348.54
Aromaticity 0.18
Instability 51.63
Isoelectric Point 4.37
Sequence ETFSDLWKLLP

Clustering Classification

Sequence cluster S 63
Contact cluster C46
Interface cluster I31

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S63) 		Contact cluster
(C46) 		Interface cluster
(I31)
3dab-B-A
3dab-D-C
3dab-H-G
3jzo-P-A
3jzp-P-A
3jzq-P-A
3jzq-Q-B
3jzr-P-A
3jzs-P-A
3lnz-J-I
1t4f-P-M
3lnz-L-K
3eqs-B-A
3eqy-D-B
2mwy-B-A
2mps-B-A
2k8f-B-A