1X2R-B-A

PDB Title STRUCTURAL BASIS FOR THE DEFECTS OF HUMAN LUNG CANCER SOMATIC MUTATIONS IN THE REPRESSION ACTIVITY OF KEAP1 ON NRF2
Resolution (Å) 1.700
Classification TRANSCRIPTION

Protein

Description Kelch-like ECH-associated protein 1
Organism Mus musculus
Chain A
Length 290
Binding Area (Å2) 444.13
Molecular Weight 31726.17
Aromaticity 0.09
Instability 41.09
Isoelectric Point 5.78
Sequence VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPC

Peptide

Description Nuclear factor erythroid 2 related factor 2
Organism Mus musculus
Chain B
Length 9
Binding Area (Å2) 625.44
Hydrophobic (% a.a.)
44%
Molecular Weight 1052.09
Aromaticity 0.11
Instability 27.30
Isoelectric Point 3.50
Sequence LDEETGEFL

Clustering Classification

Sequence cluster S 76
Contact cluster C77
Interface cluster I82

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S76) 		Contact cluster
(C77) 		Interface cluster
(I82)
5wg1-P-A
2flu-P-X
4ifl-P-X
5wfv-P-A
5x54-C-A
5x54-D-B
2dyh-B-A
2z32-B-A