6V62-Y-A

PDB Title SETD3 DOUBLE MUTANT (N255F/W273A) IN COMPLEX WITH AN ACTIN PEPTIDE WITH HIS73 REPLACED WITH LYSINE
Resolution (Å) 2.360
Classification TRANSFERASE/STRUCTURAL PROTEIN

Protein

Description Actin-histidine N-methyltransferase
Organism Homo sapiens
Chain A
Length 485
Binding Area (Å2) 1055.87
Molecular Weight -
Aromaticity 0.11
Instability -
Isoelectric Point 5.83
Sequence VSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQFQIPTEDGSRVTLALIPLADMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNHDLSVRAKMAIKLRLGEKEILEKAVKSAAVNREYYRQQMEEKAPLPKYEX

Peptide

Description Actin, cytoplasmic 1
Organism Homo sapiens
Chain Y
Length 18
Binding Area (Å2) 1340.81
Hydrophobic (% a.a.)
38%
Molecular Weight 2152.42
Aromaticity 0.11
Instability 3.02
Isoelectric Point 4.54
Sequence TLKYPIEKGIVTNWDDME

Clustering Classification

Sequence cluster S 113
Contact cluster C36
Interface cluster I1879

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S113) 		Contact cluster
(C36) 		Interface cluster
(I1879)
6ox4-Z-B
6ox5-Y-A
6v63-Y-A
6v63-Z-B
6icv-C-A
6icv-D-B
6mbj-Y-A
6mbj-Z-B
6mbk-Y-A
6mbk-Z-B
6mbl-Y-A
6ox0-Y-A
6ox0-Z-B
6ox3-Y-A
6ox3-Z-B
6ox4-Y-A
3p4n-C-D
3p4n-F-A
3p4o-C-D
3p4o-F-A
3p4m-C-D
3p4m-F-A