6HK3-N-A

PDB Title CRYSTAL STRUCTURE OF GSK-3B IN COMPLEX WITH PYRAZINE INHIBITOR C44
Resolution (Å) 2.350
Classification TRANSFERASE

Protein

Description Glycogen synthase kinase-3 beta
Organism Homo sapiens
Chain A
Length 354
Binding Area (Å2) 201.45
Molecular Weight -
Aromaticity 0.10
Instability -
Isoelectric Point 8.87
Sequence SKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSXICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHARIXXXX

Peptide

Description GLY-SER-HIS-GLY-HIS-HIS-HIS-HIS
Organism Homo sapiens
Chain N
Length 8
Binding Area (Å2) 263.30
Hydrophobic (% a.a.)
25%
Molecular Weight 904.89
Aromaticity 0.00
Instability -4.21
Isoelectric Point 7.16
Sequence GSHGHHHH

Clustering Classification

Sequence cluster S 340
Contact cluster C1715
Interface cluster I513

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S340) 		Contact cluster
(C1715) 		Interface cluster
(I513)
6hk4-N-A
3ngy-E-D
3rof-B-A
5fpx-F-B
5h0u-B-A
2v5f-X-A
3mpj-Y-B