5X54-D-B

PDB Title CRYSTAL STRUCTURE OF THE KEAP1 KELCH DOMAIN IN COMPLEX WITH A TETRAPEPTIDE
Resolution (Å) 2.300
Classification TRANSCRIPTION/TRANSCRIPTION INHIBITOR

Protein

Description Kelch-like ECH-associated protein 1
Organism Homo sapiens
Chain B
Length 285
Binding Area (Å2) 424.78
Molecular Weight 31225.58
Aromaticity 0.09
Instability 43.05
Isoelectric Point 5.83
Sequence GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT

Peptide

Description ACE-GLU-TRP-TRP-TRP
Organism Escherichia virus T7
Chain D
Length 4
Binding Area (Å2) 552.01
Hydrophobic (% a.a.)
0%
Molecular Weight 705.76
Aromaticity 0.75
Instability -30.08
Isoelectric Point 4.00
Sequence EWWW

Clustering Classification

Sequence cluster S 721
Contact cluster C73
Interface cluster I82

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S721) 		Contact cluster
(C73) 		Interface cluster
(I82)
5x54-C-A
1x2r-B-A
2dyh-B-A
2flu-P-X
2z32-B-A
4ifl-P-X
5wfv-P-A
5wg1-P-A