4TR9-I-B

PDB Title TERNARY CO-CRYSTAL STRUCTURE OF FRUCTOSE-BISPHOSPHATE ALDOLASE FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH TRAP AND A SMALL MOLECULE INHIBITOR
Resolution (Å) 2.110
Classification LYASE/LYASE INHIBITOR

Protein

Description Fructose-bisphosphate aldolase
Organism Plasmodium falciparum
Chain B
Length 348
Binding Area (Å2) 295.07
Molecular Weight -
Aromaticity 0.07
Instability -
Isoelectric Point 8.42
Sequence EYMNAPKKLPADVAEELATTAQKLVQAGKGILAADESTQTIKKRFDNIKLENTIENRASYRDLLFGTKGLGKFISGAILFEETLFQKNEAGVPMVNLLHNENIIPGIKVDKGLVNIPCTDEEKSTQGLDGLAERCKEYYKAGARFAKWRTVLVIDTAKGKPTDLSIHETAWGLARYASICQQNRLVPIVEPEILADGPHSIEVCAVVTQKVLSCVFKALQENGVLLEGALLKPNMVTAGYECTAKTTTQDVGFLTVRTLRRTVPPALPGVVFLSGGQSEEEASVNLNSINALGPHPWALTFSYGRALQASVLNTWQGKKENVAKAREVLLQRAEANSLATYGKYKGGX

Peptide

Description ASP-TRP-ASN
Organism Plasmodium falciparum
Chain I
Length 3
Binding Area (Å2) 474.96
Hydrophobic (% a.a.)
0%
Molecular Weight 433.42
Aromaticity 0.33
Instability 47.80
Isoelectric Point 3.80
Sequence DWN

Clustering Classification

Sequence cluster S 18
Contact cluster C60
Interface cluster I69

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S18) 		Contact cluster
(C60) 		Interface cluster
(I69)
4tr9-H-A
4tr9-J-C
2ot0-H-D
3lge-E-A
3lge-H-D
2ot0-E-A
2ot0-F-B
2ot0-G-C
2pc4-H-D
3lge-F-B
3lge-G-C
3iqq-B-A
3rm1-B-A
1mwn-X-A
1mwn-Y-B