4HYS-B-A

PDB Title CRYSTAL STRUCTURE OF JNK1 IN COMPLEX WITH JIP1 PEPTIDE AND 4-(4- INDAZOL-1-YL-PYRIMIDIN-2-YLAMINO)-CYCLOHEXAN
Resolution (Å) 2.420
Classification TRANSFERASE/TRANSFERASE INHIBITOR

Protein

Description Mitogen-activated protein kinase 8
Organism Homo sapiens
Chain A
Length 322
Binding Area (Å2) 515.06
Molecular Weight -
Aromaticity 0.10
Instability -
Isoelectric Point 6.83
Sequence NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPREHTIEEWKELIYKEVMX

Peptide

Description C-Jun-amino-terminal kinase-interacting protein 1
Organism Homo sapiens
Chain B
Length 9
Binding Area (Å2) 668.46
Hydrophobic (% a.a.)
44%
Molecular Weight 1039.23
Aromaticity 0.00
Instability 66.51
Isoelectric Point 11.01
Sequence PKRPTTLNL

Clustering Classification

Sequence cluster S 225
Contact cluster C38
Interface cluster I34

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S225) 		Contact cluster
(C38) 		Interface cluster
(I34)
3oxi-J-A
3ptg-J-A
4e73-B-A
4g1w-B-A
4h39-B-A
4hyu-B-A
4izy-B-A
1ukh-B-A
2xrw-B-A
4h3b-B-A
4h3b-D-C
4ux9-F-A
4ux9-G-B
4ux9-H-C
4ux9-I-D