3T6B-D-B

PDB Title STRUCTURE OF HUMAN DPPIII IN COMPLEX WITH THE OPIOID PEPTIDE TYNORPHIN, AT 2.4 ANGSTROMS
Resolution (Å) 2.400
Classification HYDROLASE/HYDROLASE INHIBITOR

Protein

Description Dipeptidyl peptidase 3
Organism Homo sapiens
Chain B
Length 724
Binding Area (Å2) 586.92
Molecular Weight 81317.74
Aromaticity 0.11
Instability 40.36
Isoelectric Point 5.03
Sequence DTQYILPNDIGVSSLDCREAFRLLSPTERLYAYHLSRAAWYGGLAVLLQTSPEAPYIYALLSRLFRAQDPDQLRQHALAEGLTEEEYQAFLVYAAGVYSNMGNYKSFGDTKFVPNLPKEKLERVILGSEAAQQHPEEVRGLWQTCGELMFSLEPRLRHLGLGKEGITTYFSGNCTMEDAKLAQDFLDSQNLSAYNTRLFKEVDGEGKPYYEVRLASVLGSEPSLDSEVTSKLKSYEFRGSPFQVTRGDYAPILQKVVEQLEKAKAYAANSHQGQMLAQYIESFTQGSIEAHKRGSRFWIQDKGPIVESYIGFIESYRDPFGSRGEFEGFVAVVNKAMSAKFERLVASAEQLLKELPWPPTFEKDKFLTPDFTSLDVLTFAGSGIPAGINIPNYDDLRQTEGFKNVSLGNVLAVAYATQREKLTFLEEDDKDLYILWKGPSFDVQVGLHALLGHGSGKLFVQDEKGAFNFDQETVINPETGEQIQSWYRSGETWDSKFSTIASSYEECRAESVGLYLCLHPQVLEIFGFEGADAEDVIYVNWLNMVRAGLLALEFYTPEAFNWRQAHMQARFVILRVLLEAGEGLVTITPTTGSDGRPDARVRLDRSKIRSVGKPALERFLRRLQVLKSTGDVAGGRALYEGYATVTDAPPECFLTLRDTVLLRKESRKLIVQPNTRLEGSDVQLLEYEASAAGLIRSFSERFPEDGPELEEILTQLATADARFW

Peptide

Description Tynorphin
Organism Homo sapiens
Chain D
Length 5
Binding Area (Å2) 816.11
Hydrophobic (% a.a.)
60%
Molecular Weight 662.78
Aromaticity 0.40
Instability 11.84
Isoelectric Point 5.49
Sequence VVYPW

Clustering Classification

Sequence cluster S 558
Contact cluster C148
Interface cluster I171

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S558) 		Contact cluster
(C148) 		Interface cluster
(I171)
3t6b-C-A
5e2q-B-A
5e33-B-A
5e3a-B-A