3IEC-E-A

PDB Title HELICOBACTER PYLORI CAGA INHIBITS PAR1/MARK FAMILY KINASES BY MIMICKING HOST SUBSTRATES
Resolution (Å) 2.200
Classification SIGNALING PROTEIN/TOXIN

Protein

Description Serine/threonine-protein kinase MARK2
Organism Homo sapiens
Chain A
Length 311
Binding Area (Å2) 823.88
Molecular Weight 35990.33
Aromaticity 0.11
Instability 38.30
Isoelectric Point 8.52
Sequence HIGNYRLLKTIGAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGWMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGY

Peptide

Description Cytotoxicity-associated immunodominant antigen
Organism Helicobacter pylori
Chain E
Length 14
Binding Area (Å2) 1054.22
Hydrophobic (% a.a.)
35%
Molecular Weight 1697.93
Aromaticity 0.07
Instability 31.16
Isoelectric Point 8.50
Sequence FPLKRHDKVDDLSK

Clustering Classification

Sequence cluster S 733
Contact cluster C252
Interface cluster I1067

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S733) 		Contact cluster
(C252) 		Interface cluster
(I1067)
3iec-G-C
3iec-H-D