2XXM-T-A

PDB Title CRYSTAL STRUCTURE OF THE HIV-1 CAPSID PROTEIN C-TERMINAL DOMAIN IN COMPLEX WITH A CAMELID VHH AND THE CAI PEPTIDE.
Resolution (Å) 1.650
Classification IMMUNE SYSTEM/PEPTIDE

Protein

Description CAPSID PROTEIN P24
Organism Human immunodeficiency virus
Chain A
Length 73
Binding Area (Å2) 581.85
Molecular Weight 8261.38
Aromaticity 0.07
Instability 50.62
Isoelectric Point 5.28
Sequence SPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPGATLEEMMTAC

Peptide

Description INHIBITOR OF CAPSID ASSEMBLY
Organism synthetic construct
Chain T
Length 11
Binding Area (Å2) 697.00
Hydrophobic (% a.a.)
45%
Molecular Weight 1348.45
Aromaticity 0.27
Instability 41.32
Isoelectric Point 3.49
Sequence ITFEDLLDYYG

Clustering Classification

Sequence cluster S 206
Contact cluster C138
Interface cluster I159