2Q0N-B-A

PDB Title STRUCTURE OF HUMAN P21 ACTIVATING KINASE 4 (PAK4) IN COMPLEX WITH A CONSENSUS PEPTIDE
Resolution (Å) 1.750
Classification TRANSFERASE

Protein

Description Serine/threonine-protein kinase PAK 4
Organism Homo sapiens
Chain A
Length 294
Binding Area (Å2) 734.25
Molecular Weight -
Aromaticity 0.06
Instability -
Isoelectric Point 8.90
Sequence RVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKXLVGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLMRQNRTR

Peptide

Description Synthetic peptide
Organism -
Chain B
Length 11
Binding Area (Å2) 931.52
Hydrophobic (% a.a.)
18%
Molecular Weight 1554.72
Aromaticity 0.27
Instability 268.55
Isoelectric Point 11.83
Sequence RRRRRSWYFDG

Clustering Classification

Sequence cluster S 84
Contact cluster C99
Interface cluster I110

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S84) 		Contact cluster
(C99) 		Interface cluster
(I110)
4jdk-B-A
4jdh-B-A
4jdi-B-A
4jdj-B-A
4xbu-B-A
4fii-B-A