2ND1-B-A

PDB Title SOLUTION NMR STRUCTURES OF BRD4 ET DOMAIN IN COMPLEX WITH NSD3_3 PEPTIDE
Resolution (Å)
Classification TRANSCRIPTION/TRANSFERASE

Protein

Description Bromodomain-containing protein 4
Organism Homo sapiens
Chain A
Length 83
Binding Area (Å2) 702.81
Molecular Weight 9726.99
Aromaticity 0.04
Instability 75.30
Isoelectric Point 7.72
Sequence SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA

Peptide

Description Histone-lysine N-methyltransferase NSD3
Organism Homo sapiens
Chain B
Length 13
Binding Area (Å2) 834.72
Hydrophobic (% a.a.)
38%
Molecular Weight 1552.90
Aromaticity 0.00
Instability 20.00
Isoelectric Point 9.83
Sequence VVPKKKIKKEQVE

Clustering Classification

Sequence cluster S 1113
Contact cluster C991
Interface cluster I126

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S1113) 		Contact cluster
(C991) 		Interface cluster
(I126)
6bnh-B-A
2n3k-B-A
2ncz-B-A
2nd0-B-A
6bgg-A-B