1EE4-D-A

PDB Title CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE
Resolution (Å) 2.100
Classification TRANSPORT PROTEIN

Protein

Description KARYOPHERIN ALPHA
Organism Saccharomyces cerevisiae
Chain A
Length 423
Binding Area (Å2) 339.69
Molecular Weight 46829.22
Aromaticity 0.05
Instability 36.78
Isoelectric Point 4.80
Sequence QELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVAEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNENDKIYEKAYKIIETYF

Peptide

Description MYC PROTO-ONCOGENE PROTEIN
Organism Homo sapiens
Chain D
Length 5
Binding Area (Å2) 464.02
Hydrophobic (% a.a.)
40%
Molecular Weight 642.83
Aromaticity 0.00
Instability 50.46
Isoelectric Point 11.17
Sequence KRVKL

Clustering Classification

Sequence cluster S 451
Contact cluster C5
Interface cluster I77

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S451) 		Contact cluster
(C5) 		Interface cluster
(I77)
1ee4-F-B
2yns-C-A
2yns-D-B
5vqi-C-B
4rxh-A-B
4b8o-C-A
4b8p-C-A
4b8p-D-B
3zin-B-A
4bqk-C-B
5b56-E-A
5huw-B-C
5vqi-A-B
6bw9-B-A
3zin-C-A
4bqk-D-A
5b56-F-B
5huy-B-C
6bwa-B-A
1ee4-C-A
3zio-B-A
4mz5-A-E
5ctt-B-A
5huy-A-C
5w41-B-A
6bwb-B-A
1ee4-E-B
3knd-B-A
3zio-C-A
4mz5-C-E
5d5k-B-C
5k9s-B-A
5w4e-A-B
6iu7-B-A
3l3q-B-A
3zip-B-A
4mz6-A-E
5e6q-A-B
5k9s-C-A
5w4e-D-B
6iua-B-A
1ee5-B-A
3l3q-C-A
3zip-C-A
4mz6-C-E
5ekf-B-A
5klr-A-B
5w4f-A-B
6k06-A-C
1pjm-A-B
3oqs-B-A
3ziq-B-A
4oih-B-A
5ekf-C-A
5svz-B-A
5w4f-D-B
6mjl-A-B
1pjn-A-B
3q5u-B-A
3ziq-C-A
5fc8-C-E
5u5p-C-A
5w4g-A-B
6p6a-A-B
1q1s-A-C
3rz9-B-A
3zir-B-A
4rxh-C-B
5gxw-B-A
5u5p-B-A
5wum-C-A
6p6a-C-B
1q1s-B-C
3tpm-B-A
3zir-C-A
4wv6-B-A
5h2w-B-A
5u5r-B-A
5wun-B-A
6p6e-B-A
1q1t-A-C
3ukx-C-B
4b8o-B-A
4wv6-C-A
5h2w-D-C
5umz-E-B
5wun-C-A
6p6e-C-A
1q1t-B-C
3uky-C-B
4xzr-A-B
5h2x-B-A
5umz-D-B
5x8n-B-A
1y2a-P-C
3ukz-C-B
4yi0-A-C
5h43-B-A
5v5o-A-C
2c1m-B-A
3ul0-C-B
5h43-C-A
5v5o-B-C
6bvv-B-A
2ynr-B-A
3ul1-A-B
4ba3-B-A
5hhg-C-E
5v5p-A-C
6bw0-C-E
2ynr-C-A
3uvu-B-A
4bpl-B-A
4zdu-B-A
5huw-A-C
5v5p-B-C
6bw1-C-E
3cbp-B-A
5y1u-C-B
4z88-T-H
4z88-V-J