4G1W-B-A

PDB Title CRYSTAL STRUCTURE OF JNK1 IN COMPLEX WITH JIP1 PEPTIDE AND 7-FLUORO-3- [4-(2-HYDROXY-ETHANESULFONYL)-BENZYL]-4-OXO-1-PHENYL-1,4-DIHYDRO- QUINOLINE-2-CARBOXYLIC ACID METHYL ESTER
Resolution (Å) 2.450
Classification TRANSFERASE/TRANSFERASE INHIBITOR

Protein

Description Mitogen-activated protein kinase 8
Organism Homo sapiens
Chain A
Length 323
Binding Area (Å2) 537.41
Molecular Weight -
Aromaticity 0.10
Instability -
Isoelectric Point 6.83
Sequence NNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPREHTIEEWKELIYKEVMX

Peptide

Description C-Jun-amino-terminal kinase-interacting protein 1
Organism Homo sapiens
Chain B
Length 9
Binding Area (Å2) 663.33
Hydrophobic (% a.a.)
44%
Molecular Weight 1039.23
Aromaticity 0.00
Instability 66.51
Isoelectric Point 11.01
Sequence PKRPTTLNL

Clustering Classification

Sequence cluster S 225
Contact cluster C43
Interface cluster I34

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S225) 		Contact cluster
(C43) 		Interface cluster
(I34)
4izy-B-A
1ukh-B-A
3oxi-J-A
3ptg-J-A
4e73-B-A
4h39-B-A
4hys-B-A
4hyu-B-A
4ux9-F-A
4ux9-G-B
4ux9-H-C
4ux9-I-D
2xrw-B-A
4h3b-B-A
4h3b-D-C