2ILM-S-A

PDB Title FACTOR INHIBITING HIF-1 ALPHA D201A MUTANT IN COMPLEX WITH FE(II), ALPHA-KETOGLUTARATE AND HIF-1 ALPHA 35MER
Resolution (Å) 2.300
Classification TRANSCRIPTION REGULATOR, OXIDOREDUCTA

Protein

Description Hypoxia-inducible factor 1 alpha inhibitor
Organism Homo sapiens
Chain A
Length 344
Binding Area (Å2) 321.70
Molecular Weight -
Aromaticity 0.13
Instability -
Isoelectric Point 5.48
Sequence AVASGSGEPREEAGALGPAWDESQLRSYSFPTRPIPRLSQSDPRAEELIENEEPVVLTDTNLVYPALKWDLEYLQENIGNGDFSVYSASTHKFLYYDEKKMANFQNFKPRSNREEMKFHEFVEKLQDIQQRGGEERLYLQQTLNDTVGRKIVMDFLGFNWNWINKQQGKRGWGQLTSNLLLIGMEGNVTPAHYAEQQNFFAQIKGYKRCILFPPDQFECLYPYPVHHPCDRQSQVDFDNPDYERFPNFQNVVGYETVVGPGDVLYIPMYWWHHIESLLNGGITITVNFWYKGAPTPKIEYPLKAHQKVAIMRNIEKMLGEALGNPQEVGPLLNTMIKGRYNXXX

Peptide

Description Hypoxia-inducible factor 1 alpha
Organism Homo sapiens
Chain S
Length 6
Binding Area (Å2) 368.25
Hydrophobic (% a.a.)
16%
Molecular Weight 725.74
Aromaticity 0.17
Instability 47.80
Isoelectric Point 4.30
Sequence QLTSYD

Clustering Classification

Sequence cluster S 34
Contact cluster C39
Interface cluster I781

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S34) 		Contact cluster
(C39) 		Interface cluster
(I781)
1h2k-S-A
1h2l-S-A
1h2m-S-A
3d8c-B-A
5jwp-B-A
6h9j-D-A
6ha6-D-A
6hc8-E-A
6hkp-S-A
6hl5-S-A
6hl6-S-A
2xum-S-A
2y0i-S-A
3p3n-B-A
4b7e-B-A
4b7k-B-A
1l3e-A-B