1UOO-B-A

PDB Title PROLYL OLIGOPEPTIDASE FROM PORCINE BRAIN, S554A MUTANT WITH BOUND PEPTIDE LIGAND GLY-PHE-ARG-PRO
Resolution (Å) 2.350
Classification HYDROLASE

Protein

Description PROLYL ENDOPEPTIDASE
Organism Sus scrofa
Chain A
Length 710
Binding Area (Å2) 304.67
Molecular Weight 80752.62
Aromaticity 0.13
Instability 33.94
Isoelectric Point 5.52
Sequence MLSFQYPDVYRDETAIQDYHGHKVCDPYAWLEDPDSEQTKAFVEAQNKITVPFLEQCPIRGLYKERMTELYDYPKYSCHFKKGKRYFYFYNTGLQNQRVLYVQDSLEGEARVFLDPNILSDDGTVALRGYAFSEDGEYFAYGLSASGSDWVTIKFMKVDGAKELPDVLERVKFSCMAWTHDGKGMFYNAYPQQDGKSDGTETSTNLHQKLYYHVLGTDQSEDILCAEFPDEPKWMGGAELSDDGRYVLLSIREGCDPVNRLWYCDLQQESNGITGILKWVKLIDNFEGEYDYVTNEGTVFTFKTNRHSPNYRLINIDFTDPEESKWKVLVPEHEKDVLEWVACVRSNFLVLCYLHDVKNTLQLHDLATGALLKIFPLEVGSVVGYSGQKKDTEIFYQFTSFLSPGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLDGSHPAFLYGYGGFNISITPNYSVSRLIFVRHMGGVLAVANIRGGGEYGETWHKGGILANKQNCFDDFQCAAEYLIKEGYTSPKRLTINGGANGGLLVATCANQRPDLFGCVIAQVGVMDMLKFHKYTIGHAWTTDYGCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTADHDDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFAFIARCLNIDWIP

Peptide

Description PEPTIDE LIGAND GLY-PHE-ARG-PRO
Organism synthetic construct
Chain B
Length 4
Binding Area (Å2) 489.12
Hydrophobic (% a.a.)
75%
Molecular Weight 475.54
Aromaticity 0.25
Instability 55.65
Isoelectric Point 9.75
Sequence GFRP

Clustering Classification

Sequence cluster S 738
Contact cluster C255
Interface cluster I239

Similar complexes

Is the complex classified in the same cluster?

Complex Sequence cluster
(S738) 		Contact cluster
(C255) 		Interface cluster
(I239)
1uop-B-A
1uoq-B-A
1fzc-G-C
1fzc-H-F
2fib-B-A