National Center for Biotechnology Information, NIH, 45 Center Drive, Bethesda, MD 20892-6510, USA. ogurtsov@ncbi.nlm.nih.gov|National Center for Biotechnology Information, NIH, 45 Center Drive, Bethesda, MD 20892-6510, USA. ogurtsov@ncbi.nlm.nih.gov|National Center for Biotechnology Information, NIH, 45 Center Drive, Bethesda, MD 20892-6510, USA. ogurtsov@ncbi.nlm.nih.gov|National Center for Biotechnology Information, NIH, 45 Center Drive, Bethesda, MD 20892-6510, USA. ogurtsov@ncbi.nlm.nih.gov