Inria Bordeaux Sud-Ouest, Institut de Mathxc3xa9matiques de Bordeaux, Bordeaux, France, Center of Cancer Systems Biology, GRI, Tufts University School of Medicine, Boston, Massachusetts, United States of America.|Center of Cancer Systems Biology, GRI, Tufts University School of Medicine, Boston, Massachusetts, United States of America.|Center of Cancer Systems Biology, GRI, Tufts University School of Medicine, Boston, Massachusetts, United States of America.|Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America.|Department of Medicine, Roswell Park Cancer Institute, Buffalo, New York, United States of America.|Center of Cancer Systems Biology, GRI, Tufts University School of Medicine, Boston, Massachusetts, United States of America.|Center of Cancer Systems Biology, GRI, Tufts University School of Medicine, Boston, Massachusetts, United States of America.