Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.|Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America.|School of Mathematics, Statistics and Computer Science, University of Tehran, Tehran, Iran, School of Computer Science, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.|Department of Biomedical Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.