Computational Bioscience Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.|Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.|Computational Bioscience Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.|Department of Medical Oncology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.|Computational Bioscience Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.