Computational Biology, Department of Physics, Linköping University, SE58183 Linköping, Sweden. rnilsson@broad.mit.edu|Computational Biology, Department of Physics, Linköping University, SE58183 Linköping, Sweden. rnilsson@broad.mit.edu|Computational Biology, Department of Physics, Linköping University, SE58183 Linköping, Sweden. rnilsson@broad.mit.edu