Department of Biostatistics and Applied Mathematics, UT M. D. Anderson Cancer Center, Houston, TX, USA. kabagg@mdanderson.org|Department of Biostatistics and Applied Mathematics, UT M. D. Anderson Cancer Center, Houston, TX, USA. kabagg@mdanderson.org|Department of Biostatistics and Applied Mathematics, UT M. D. Anderson Cancer Center, Houston, TX, USA. kabagg@mdanderson.org|Department of Biostatistics and Applied Mathematics, UT M. D. Anderson Cancer Center, Houston, TX, USA. kabagg@mdanderson.org