Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. spencers@mit.edu|Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. spencers@mit.edu|Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. spencers@mit.edu|Computational and Systems Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. spencers@mit.edu