Bioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, California, United States of America.|Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America.|Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America.|Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America.