School of Biological and Chemical Sciences, Queen Mary University of London, London, UK.|Department of Computer Science, College of Engineering, Design and Physical Sciences and Synthetic Biology Theme, Institute of Environment, Health and Societies, Brunel University London, Uxbridge, London, UK.|Randall Division of Cell and Molecular Biophysics, Kings College London, London, UK.|School of Biological and Chemical Sciences, Queen Mary University of London, London, UK.