Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org|Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY 10065, USA. pihelper@cbio.mskcc.org