Department of Preventive Medicine ,Biostatistics Division, University of Southern California, Los Angeles, California, United States of America.|Department of Electrical and Computer Engineering, Rice University, Houston, Texas, United States of America.|Department of Statistics, University of Washington, Seattle, Washington, United States of America.|Department of Biomathematics, University of California, Los Angeles, Los Angeles, California, United States of America, Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America, Department of Statistics, University of California, Los Angeles, Los Angeles, California, United States of America.