Computational and Evolutionary Biology, Faculty of Life Sciences, University of Manchester, Manchester, UK. john.archer@manchester.ac.uk|Computational and Evolutionary Biology, Faculty of Life Sciences, University of Manchester, Manchester, UK. john.archer@manchester.ac.uk|Computational and Evolutionary Biology, Faculty of Life Sciences, University of Manchester, Manchester, UK. john.archer@manchester.ac.uk|Computational and Evolutionary Biology, Faculty of Life Sciences, University of Manchester, Manchester, UK. john.archer@manchester.ac.uk|Computational and Evolutionary Biology, Faculty of Life Sciences, University of Manchester, Manchester, UK. john.archer@manchester.ac.uk|Computational and Evolutionary Biology, Faculty of Life Sciences, University of Manchester, Manchester, UK. john.archer@manchester.ac.uk