Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA.|Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA.|Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA.|Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90024, USA.