Department of Biostatistics, St. Jude Childrens Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. stanley.pounds@stjude.org|Department of Biostatistics, St. Jude Childrens Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. stanley.pounds@stjude.org|Department of Biostatistics, St. Jude Childrens Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. stanley.pounds@stjude.org|Department of Biostatistics, St. Jude Childrens Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. stanley.pounds@stjude.org|Department of Biostatistics, St. Jude Childrens Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. stanley.pounds@stjude.org|Department of Biostatistics, St. Jude Childrens Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. stanley.pounds@stjude.org