Wolfson Institute for Biomedical Research and Department of Physiology, University College London, London, UK. h.cuntz@ucl.ac.uk|Wolfson Institute for Biomedical Research and Department of Physiology, University College London, London, UK. h.cuntz@ucl.ac.uk|Wolfson Institute for Biomedical Research and Department of Physiology, University College London, London, UK. h.cuntz@ucl.ac.uk|Wolfson Institute for Biomedical Research and Department of Physiology, University College London, London, UK. h.cuntz@ucl.ac.uk