Centre for Bioinformatics Tübingen (ZBIT), University of Tübingen Sand 1, 72076 Tübingen, Germany. christian.spieth@uni-tuebingen.de|Centre for Bioinformatics Tübingen (ZBIT), University of Tübingen Sand 1, 72076 Tübingen, Germany. christian.spieth@uni-tuebingen.de|Centre for Bioinformatics Tübingen (ZBIT), University of Tübingen Sand 1, 72076 Tübingen, Germany. christian.spieth@uni-tuebingen.de|Centre for Bioinformatics Tübingen (ZBIT), University of Tübingen Sand 1, 72076 Tübingen, Germany. christian.spieth@uni-tuebingen.de|Centre for Bioinformatics Tübingen (ZBIT), University of Tübingen Sand 1, 72076 Tübingen, Germany. christian.spieth@uni-tuebingen.de