Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. joe.zhu@well.ox.ac.uk.|Department of Mathematics and Statistics, University of New Mexico, Albuquerque, New Mexico, USA. jamdeg@unm.edu.|Department of Biology, University of Canterbury, Christchurch, New Zealand. sharyn.goldstien@canterbury.ac.nz.|Institut für Mathematik, Technische Universität Berlin, Berlin, Germany. eldon@math.tu-berlin.de.