Bioinformatics Institute, Matrix, Singapore 138671. jiren@bii.a-star.edu.sg|Bioinformatics Institute, Matrix, Singapore 138671. jiren@bii.a-star.edu.sg|Bioinformatics Institute, Matrix, Singapore 138671. jiren@bii.a-star.edu.sg|Bioinformatics Institute, Matrix, Singapore 138671. jiren@bii.a-star.edu.sg