Fraunhofer MEVIS, Bremen, Germany.|Computational Systems Biology, Bayer Technology Services, Leverkusen, Germany, Aachen Institute for Advanced Study in Computational Engineering Sciences, RWTH Aachen University, Aachen, Germany.|Computational Systems Biology, Bayer Technology Services, Leverkusen, Germany.|Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany.|Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany.|Fraunhofer MEVIS, Bremen, Germany.|Fraunhofer MEVIS, Bremen, Germany, School of Engineering and Science, Jacobs University, Bremen, Germany.|Computational Systems Biology, Bayer Technology Services, Leverkusen, Germany, Institute of Applied Microbiology, RWTH Aachen University, Aachen, Germany.