Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.|Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.|Biology Department, Reed College, Portland, OR 97202, USA.|Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.|RedOwl Analytics, Baltimore, MD 21230, USA.|Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, USA.|Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO 80523, USA.|Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.|Biocomplexity Institute.|Department of Chemical and Biological Engineering, Colorado State University, Fort Collins, CO 80523, USA.|Department of Biological Sciences, Virginia Tech, Blacksburg, VA 24061, USA.|Department of Computer Science, Virginia Tech, Blacksburg, VA 24061, USA.