Institute for Computing and Information Sciences, Radboud University Nijmegen, Nijmegen, The Netherlands. t.heskes@science.ru.nl.|Department of Social Science Research Methods, Radboud University Nijmegen, Nijmegen, The Netherlands. r.eisinga@maw.ru.nl.|Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, UK. rainer.breitling@manchester.ac.uk.