Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. erobert3@scs.uiuc.edu|Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. erobert3@scs.uiuc.edu|Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. erobert3@scs.uiuc.edu|Center for Biophysics and Computational Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. erobert3@scs.uiuc.edu