Department of Computer Science, University of Oxford, Oxford, United Kingdom, Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.|Department of Computer Science, University of Oxford, Oxford, United Kingdom.|Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.|Department of Medicine, Louis Stokes Department of Veterans Affairs Hospital, Cleveland Ohio, United States of America.|Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.|School of Electrical Engineering and Computing Systems, University of Cincinnati, Cincinnati, Ohio, United States of America.|Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.|Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.|Department of Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom.