Department of Biostatistics, Boston University, Boston, MA.|Bioinformatics Program, Boston University, Boston, MA.|gRED Oncology Biostatistics, Genentech, South San Francisco, CA.|Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.|Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA.|Departments of Medical Biophysics and Computer Science, University of Toronto, Toronto, Ontario, Canada.|Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD.|Department of Biostatistics, Boston University, Boston, MA.