CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China. a.teschendorff@ucl.ac.uk.|Department of Womens Cancer, University College London, 74 Huntley Street, London, WC1E 6AU, UK.|Department of Womens Cancer, University College London, 74 Huntley Street, London, WC1E 6AU, UK. m.widschwendter@ucl.ac.uk.