Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. msmoot@ucsd.edu|Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. msmoot@ucsd.edu|Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. msmoot@ucsd.edu|Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. msmoot@ucsd.edu|Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. msmoot@ucsd.edu