Center for Systems Biology (ZBSA), University of Freiburg, Freiburg 79104, Germany.|Helmholtz Zentrum München - German Research Center for Environmental Health, Institute of Computational Biology, Neuherberg 85764, Germany.|Helmholtz Zentrum München - German Research Center for Environmental Health, Institute of Computational Biology, Neuherberg 85764, Germany.|Center for Systems Biology (ZBSA), University of Freiburg, Freiburg 79104, Germany.|Helmholtz Zentrum München - German Research Center for Environmental Health, Institute of Computational Biology, Neuherberg 85764, Germany.|Center for Systems Biology (ZBSA), University of Freiburg, Freiburg 79104, Germany.