Department of Biology, University of Pennsylvania, 433 S. University Ave., Philadelphia, PA, 19104, USA.|Department of Biology, University of Pennsylvania, 433 S. University Ave., Philadelphia, PA, 19104, USA.|Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.|Department of Computer Engineering, Antalya International University, Antalya, Turkey.|Genomics and Computational Biology Graduate Group, Philadelphia, USA.|Department of Biology, University of Pennsylvania, 433 S. University Ave., Philadelphia, PA, 19104, USA. bdgregor@sas.upenn.edu.