Amino Acid Sequence|Amino Acids|Binding Sites|Computer Simulation|Ligands|Models, Chemical|Models, Molecular|Models, Statistical|Molecular Sequence Data|Multiprotein Complexes|Mutagenesis, Site-Directed|Protein Binding|Protein Conformation|Protein Interaction Mapping|Proteins|Sequence Analysis, Protein|Stochastic Processes|Structure-Activity Relationship