Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.|Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.|Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.|Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.|Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.|Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.|Computational Biology Center, IBM T J Watson Research, Yorktown Heights, NY 10598, USA.