Center for Applied Mathematics, Tianjin University, Tianjin 300072, China.|Department of Preventive Medicine.|Department of Preventive Medicine.|Department of Preventive Medicine.|Department of Preventive Medicine.|Department of Statistics, Northwestern University, Chicago, IL 60611, USA.|Department of Preventive Medicine.|Department of Environmental Health, Harvard University, Boston, MA 02115, USA.|Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.|Department of Environmental Health, Harvard University, Boston, MA 02115, USA.|Veterans Affairs Boston Healthcare System and Boston University School of Medicine, VA Normative Aging Study, Boston, MA 02118, USA.|Department of Preventive Medicine.|Data Sciences and Operations Department, University of Southern California, Los Angeles, CA 90089, USA.|Department of Environmental Health, Harvard University, Boston, MA 02115, USA.|Department of Preventive Medicine.|Department of Preventive Medicine.