Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk|Department of Oncology, University of Cambridge, Cambridge, UK. helen.field@srl.cam.ac.uk