Biostatisties, PGRD, 2800 Plymouth Road, Ann Arbor, MI 48105, USA. michael.man@pfizer.com|Biostatisties, PGRD, 2800 Plymouth Road, Ann Arbor, MI 48105, USA. michael.man@pfizer.com|Biostatisties, PGRD, 2800 Plymouth Road, Ann Arbor, MI 48105, USA. michael.man@pfizer.com