Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridge, UK. ap3@sanger.ac.uk|Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridge, UK. ap3@sanger.ac.uk|Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus Hinxton, Cambridge, UK. ap3@sanger.ac.uk