Institute for Computational Biomedicine and Dept. of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10021, USA. fac2003@med.cornell.edu|Institute for Computational Biomedicine and Dept. of Physiology and Biophysics, Weill Medical College of Cornell University, New York, NY 10021, USA. fac2003@med.cornell.edu