Department of Systems and Information Engineering, University of Virginia, Charlottesville, Virginia, United States of America.|Department of Systems and Information Engineering, University of Virginia, Charlottesville, Virginia, United States of America.|Medical Scientist Training Program, Columbia University College of Physicians & Surgeons, New York, New York, United States of America.|Department of Mechanical and Aerospace Engineering, University of Virginia, Charlottesville, Virginia, United States of America.|Department of Physiology & Cellular Biophysics, Columbia University College of Physicians & Surgeons, New York, New York, United States of America.