Department of Pediatrics, Cincinnati Childrens Hospital and Medical Center, Cincinnati, OH, USA. peter.white@cchmc.org.|Department of Pediatrics, Cincinnati Childrens Hospital and Medical Center, Cincinnati, OH, USA. peter.white@cchmc.org.|Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel. ehud.shapiro@weizmann.ac.il.