Department of Genetics, The Hospital for Sick Children, Room 9107, Toronto, Ontario, M5G 1X8, Canada. alex@genet.sickkids.on.ca|Department of Genetics, The Hospital for Sick Children, Room 9107, Toronto, Ontario, M5G 1X8, Canada. alex@genet.sickkids.on.ca|Department of Genetics, The Hospital for Sick Children, Room 9107, Toronto, Ontario, M5G 1X8, Canada. alex@genet.sickkids.on.ca|Department of Genetics, The Hospital for Sick Children, Room 9107, Toronto, Ontario, M5G 1X8, Canada. alex@genet.sickkids.on.ca