Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK. r.liberal@imperial.ac.uk.|Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2, 7AY, UK. b.k.lisowska@bath.ac.uk.|Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2, 7AY, UK. d.j.leak@bath.ac.uk.|Centre for Integrative Systems Biology and Bioinformatics, Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK. j.pinney@imperial.ac.uk.