Department of Computer Science, University of Helsinki, Helsinki, Finland , Department of Medical Genetics, Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland.|VTT Technical Research Centre of Finland, Espoo, Finland.|Department of Computer Science, University of Helsinki, Helsinki, Finland , Department of Information and Computer Science, Aalto University, Espoo, Finland.|VTT Technical Research Centre of Finland, Espoo, Finland.|VTT Technical Research Centre of Finland, Espoo, Finland.|Department of Information and Computer Science, Aalto University, Espoo, Finland.|VTT Technical Research Centre of Finland, Espoo, Finland.|Institute of Biotechnology & Department of Biosciences, University of Helsinki, Helsinki, Finland.|VTT Technical Research Centre of Finland, Espoo, Finland.|Department of Information and Computer Science, Aalto University, Espoo, Finland.|VTT Technical Research Centre of Finland, Espoo, Finland.