Department of Computer Science, Princeton University, Princeton, New Jersey, United States of America.|King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, Thuwal, Saudi Arabia.|Institute for Genomics and Systems Biology, Computation Institute, Departments of Medicine and Human Genetics, University of Chicago, Chicago, Illinois, United States of America.