Institute of Medical Microbiology, University Hospital of Dusseldorf, Dusseldorf, North Rhine-Westphalia, Germany.|Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.|Laboratoire dImmunoRhumatologie Molxc3xa9culaire, Plateforme GENOMAX, INSERM UMR_S 1109, LabEx TRANSPLANTEX, Fxc3xa9dxc3xa9ration de Mxc3xa9decine Translationnelle de Strasbourg (FMTS), Facultxc3xa9 de Mxc3xa9decine, Universitxc3xa9 de Strasbourg, France. Service dImmunologie Biologique, Nouvel Hxc3xb4pital Civil, Strasbourg, France.|Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.|Histogenetics, Ossining, United States of America.|Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.|Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.|Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.|Laboratoire dImmunoRhumatologie Molxc3xa9culaire, Plateforme GENOMAX, INSERM UMR_S 1109, LabEx TRANSPLANTEX, Fxc3xa9dxc3xa9ration de Mxc3xa9decine Translationnelle de Strasbourg (FMTS), Facultxc3xa9 de Mxc3xa9decine, Universitxc3xa9 de Strasbourg, France. Service dImmunologie Biologique, Nouvel Hxc3xb4pital Civil, Strasbourg, France.|Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.|Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.