Department of Biostatistics, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.|Department of Biostatistics, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.|Department of Biostatistics, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.|Department of Biostatistics, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.|Department of Biostatistics, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.|Department of Biostatistics, The University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.