Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan.|Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan.|Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan.|Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan.|Institute of Biomedical Informatics, National Yang Ming University, Taipei, Taiwan.