Institute of Computational Science, Faculty of Informatics, USI Lugano, Lugano, Switzerland.|NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.|BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology (SMART) Centre, Singapore, Singapore.|NUS Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore.|Institute of Computational Science, Faculty of Informatics, USI Lugano, Lugano, Switzerland.