College of Computer and Control Engineering, Nankai University, Tianjin 300350, China.|Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.|College of Computer and Control Engineering, Nankai University, Tianjin 300350, China.|Department of Statistics, Rice University, Houston, TX, 77030 USA.|Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX 77030, USA.