Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. ballman@mayo.edu|Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. ballman@mayo.edu|Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. ballman@mayo.edu|Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA. ballman@mayo.edu