mimicMe is a web server for prediction and analysis of host-like proteins (mimics) encoded by microbial pathogens. Users select a host species and any set of pathogen and control proteomes (bacterial, fungal, protozoan or viral) and mimicMe reports host-like proteins that are unique to or enriched among pathogens. Additional server features include visualization of structural similarities between pathogen and host proteins as well as function-enrichment analysis.