BioProcess Engineering Group, IIM-CSIC, Spanish National Research Council, 36208 Vigo, Spain.|BioProcess Engineering Group, IIM-CSIC, Spanish National Research Council, 36208 Vigo, Spain.|Department of Mathematics, University of A Coruña Campus Elviña s/n, 15071 A Coruña, Spain.|BioProcess Engineering Group, IIM-CSIC, Spanish National Research Council, 36208 Vigo, Spain.