Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America. dsg@mbi.osu.edu|Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America. dsg@mbi.osu.edu|Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America. dsg@mbi.osu.edu|Mathematical Biosciences Institute, The Ohio State University, Columbus, Ohio, United States of America. dsg@mbi.osu.edu