Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.