MOE Key Laboratory of Bioinformatics, Bioinformatics Division and Center for Synthetic and Systems Biology, TNLIST/Department of Automation and School of Life Sciences, Tsinghua University, Beijing 100084, China.|MOE Key Laboratory of Bioinformatics, Bioinformatics Division and Center for Synthetic and Systems Biology, TNLIST/Department of Automation and School of Life Sciences, Tsinghua University, Beijing 100084, China.