Channing Division of Network Medicine, Brigham and Womens Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America.|Harvard Medical School, Boston, Massachusetts, United States of America, Childrens Hospital Informatics Program, Childrens Hospital Boston, Boston, Massachusetts, United States of America.|Channing Division of Network Medicine, Brigham and Womens Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Partners Health Care Center for Personalized Medicine, Boston, Massachusetts, United States of America.