Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, United States of America, Center for Modeling and Simulation in the Biosciences, Heidelberg University, Heidelberg, Germany.|Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.|Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.|Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.|Department of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America.|Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, United States of America.|Los Alamos National Laboratory, Theoretical Biology and Biophysics, Los Alamos, New Mexico, United States of America.