Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. ingmar.glauche@imise.uni-leipzig.de|Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. ingmar.glauche@imise.uni-leipzig.de|Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. ingmar.glauche@imise.uni-leipzig.de|Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. ingmar.glauche@imise.uni-leipzig.de|Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. ingmar.glauche@imise.uni-leipzig.de|Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany. ingmar.glauche@imise.uni-leipzig.de