Department Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. ivan.filho@molgen.mpg.de|Department Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. ivan.filho@molgen.mpg.de|Department Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. ivan.filho@molgen.mpg.de|Department Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. ivan.filho@molgen.mpg.de