Department of Biomedical Informatics, University of Pittsburgh, 5607 Baum Blvd, 15237, Pittsburgh, PA, USA. luc17@pitt.edu.|Department of Biomedical Informatics, University of Pittsburgh, 5607 Baum Blvd, 15237, Pittsburgh, PA, USA. chunhuic@pitt.edu.|Department of Biomedical Informatics, University of Pittsburgh, 5607 Baum Blvd, 15237, Pittsburgh, PA, USA. vic14@pitt.edu.|Department of Biomedical Informatics, University of Pittsburgh, 5607 Baum Blvd, 15237, Pittsburgh, PA, USA. xinghua@pitt.edu.