Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou Street, Athens, 115 27, Greece. argisake@gmail.gr.|Center of Systems Biology, Biomedical Research Foundation of the Academy of Athens, 4 Soranou Ephessiou Street, Athens, 115 27, Greece. gspyrou@bioacademy.gr.