Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America.|Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, United States of America.|Department of Anesthesiology and Pain Medicine, Mitochondria and Metabolism Center, University of Washington School of Medicine, Seattle, Washington, United States of America.|Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America.|Department of Anesthesiology and Pain Medicine, Mitochondria and Metabolism Center, University of Washington School of Medicine, Seattle, Washington, United States of America.|Department of Anesthesiology and Pain Medicine, Mitochondria and Metabolism Center, University of Washington School of Medicine, Seattle, Washington, United States of America.|Department of Anesthesiology and Pain Medicine, Mitochondria and Metabolism Center, University of Washington School of Medicine, Seattle, Washington, United States of America.|Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America.