Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK. k.mills@qub.ac.uk.|Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, BT9 7AE, UK. s.zhang@qub.ac.uk.