MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.|MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.