Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it|Epidemiology and Biostatistics, National Cancer Research Institute, Genova, Italy. stefano.moretti@istge.it