Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43221, USA.|Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43221, USA.|Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43221, USA.|Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43221, USA.|Department of Biomedical Informatics, The Ohio State University, Columbus, OH 43221, USA.