Center for Systems Biology, School of Computer Science and Technology, Soochow University, Suzhou 215006, China and Department of Experimental Medical Science, Lund University, Lund SE 221 84, Sweden.|Department of Experimental Medical Science, Lund University, Lund SE 221 84, Sweden.|Center for Systems Biology.|Department of Experimental Medical Science, Lund University, Lund SE 221 84, Sweden.