Childrens Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. vdmarinescu@chip.org|Childrens Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. vdmarinescu@chip.org|Childrens Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. vdmarinescu@chip.org