Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA. xgu@iastate.edu|Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA. xgu@iastate.edu|Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA. xgu@iastate.edu|Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA. xgu@iastate.edu