Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.