Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Japan. tyoyo@kuicr.kyoto-u.ac.jp.|Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Japan. morihiro@kuicr.kyoto-u.ac.jp.|Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Japan. caoyue@kuicr.kyoto-u.ac.jp.|Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Japan. hwangjw@kuicr.kyoto-u.ac.jp.|Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji, Japan. takutsu@kuicr.kyoto-u.ac.jp.