Bioinformatics and Computational Life-Sciences Laboratory, ITTC, Department of Electrical Engineering and Computer Science, The University of Kansas, Lawrence, KS 66045, USA. xwchen@ku.edu|Bioinformatics and Computational Life-Sciences Laboratory, ITTC, Department of Electrical Engineering and Computer Science, The University of Kansas, Lawrence, KS 66045, USA. xwchen@ku.edu