CRG, Systems Biology program, Dr Aiguader 88, E-08003 Barcelona, Spain. raik.gruenberg@crg.es|CRG, Systems Biology program, Dr Aiguader 88, E-08003 Barcelona, Spain. raik.gruenberg@crg.es|CRG, Systems Biology program, Dr Aiguader 88, E-08003 Barcelona, Spain. raik.gruenberg@crg.es