Center for Computational Pharmacology, University of Colorado Denver, Aurora, CO 80045, USA. karin.verspoor@ucdenver.edu|Center for Computational Pharmacology, University of Colorado Denver, Aurora, CO 80045, USA. karin.verspoor@ucdenver.edu|Center for Computational Pharmacology, University of Colorado Denver, Aurora, CO 80045, USA. karin.verspoor@ucdenver.edu|Center for Computational Pharmacology, University of Colorado Denver, Aurora, CO 80045, USA. karin.verspoor@ucdenver.edu