UCLA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1678, USA. coles@ucla.edu|UCLA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1678, USA. coles@ucla.edu|UCLA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1678, USA. coles@ucla.edu|UCLA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1678, USA. coles@ucla.edu|UCLA Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1678, USA. coles@ucla.edu