Laboratory of Experimental and Computational Biology, NCI Center for Cancer Research, National Cancer Institute, NIH, Bldg 469, Room 151, Frederick, MD 21702, USA. shuyun@orleans.ncifcrf.gov|Laboratory of Experimental and Computational Biology, NCI Center for Cancer Research, National Cancer Institute, NIH, Bldg 469, Room 151, Frederick, MD 21702, USA. shuyun@orleans.ncifcrf.gov|Laboratory of Experimental and Computational Biology, NCI Center for Cancer Research, National Cancer Institute, NIH, Bldg 469, Room 151, Frederick, MD 21702, USA. shuyun@orleans.ncifcrf.gov|Laboratory of Experimental and Computational Biology, NCI Center for Cancer Research, National Cancer Institute, NIH, Bldg 469, Room 151, Frederick, MD 21702, USA. shuyun@orleans.ncifcrf.gov