School of Computer Science and Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, China, School of Information Science & Engineering, Central South University, Changsha 410083, China, Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji 611-0011, Japan and Center for Computational System Biology, Fudan University, Shanghai 200433, China School of Computer Science and Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, China, School of Information Science & Engineering, Central South University, Changsha 410083, China, Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji 611-0011, Japan and Center for Computational System Biology, Fudan University, Shanghai 200433, China School of Computer Science and Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, China, School of Information Science & Engineering, Central South University, Changsha 410083, China, Department of Computer Science, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji 611-0011, Japan and Center for Computational System Biology, Fudan University, Shanghai 200433, China.