Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH 44106, USA. gurkan@case.edu|Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH 44106, USA. gurkan@case.edu|Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH 44106, USA. gurkan@case.edu