Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Baltzerstrasse 6, 3012, Berne, Switzerland. cedric.simillion@dkf.unibe.ch.|Vital-IT, SIB Swiss Institute of Bioinformatics, Quartier Sorge - Batiment Genopode, 1015, Lausanne, Switzerland.|Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Baltzerstrasse 6, 3012, Berne, Switzerland.|Vital-IT, SIB Swiss Institute of Bioinformatics, Quartier Sorge - Batiment Genopode, 1015, Lausanne, Switzerland.|Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Baltzerstrasse 6, 3012, Berne, Switzerland. remy.bruggmann@bioinformatics.unibe.ch.