Institute of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK and School of Computing, University of Leeds, Leeds, LS2 9JT, UK.|Institute of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK and School of Computing, University of Leeds, Leeds, LS2 9JT, UK.|Institute of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK and School of Computing, University of Leeds, Leeds, LS2 9JT, UK.|Institute of Molecular and Cellular Biology, University of Leeds, Leeds, LS2 9JT, UK and School of Computing, University of Leeds, Leeds, LS2 9JT, UK.