Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA. clc196@pitt.edu