Center for Bioinformatics and Computational Biology, University of Maryland - College Park, MD 20742, USA.|Center for Bioinformatics and Computational Biology, University of Maryland - College Park, MD 20742, USA.|Center for Bioinformatics and Computational Biology, University of Maryland - College Park, MD 20742, USA.|Center for Bioinformatics and Computational Biology, University of Maryland - College Park, MD 20742, USA.