Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department, 1520 West 15th Street, The University of Kansas, Lawrence, KS 66045, USA. xwchen@ku.edu|Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department, 1520 West 15th Street, The University of Kansas, Lawrence, KS 66045, USA. xwchen@ku.edu|Bioinformatics and Computational Life Sciences Laboratory, Electrical Engineering and Computer Science Department, 1520 West 15th Street, The University of Kansas, Lawrence, KS 66045, USA. xwchen@ku.edu