Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Hasselt, 3500, Belgium. marijke.vanmoerbeke@uhasselt.be.|Wolfson Research Institute for Health and Wellbeing, Durham University, Durham, UK.|Janssen Pharmaceutica, Beerse, 2340, Belgium.|Janssen Pharmaceutica, Beerse, 2340, Belgium.|Janssen Pharmaceutica, Beerse, 2340, Belgium.|Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Hasselt, 3500, Belgium.