Quantitative Biomedical Research Center, Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Min.Chen@UTSouthwestern.edu|Quantitative Biomedical Research Center, Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Min.Chen@UTSouthwestern.edu|Quantitative Biomedical Research Center, Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Min.Chen@UTSouthwestern.edu|Quantitative Biomedical Research Center, Department of Clinical Sciences, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Min.Chen@UTSouthwestern.edu