Department of Applied Statistics, College of Medicine, Yonsei University Seoul, South Korea. bskim@yonsei.ac.kr|Department of Applied Statistics, College of Medicine, Yonsei University Seoul, South Korea. bskim@yonsei.ac.kr|Department of Applied Statistics, College of Medicine, Yonsei University Seoul, South Korea. bskim@yonsei.ac.kr|Department of Applied Statistics, College of Medicine, Yonsei University Seoul, South Korea. bskim@yonsei.ac.kr|Department of Applied Statistics, College of Medicine, Yonsei University Seoul, South Korea. bskim@yonsei.ac.kr|Department of Applied Statistics, College of Medicine, Yonsei University Seoul, South Korea. bskim@yonsei.ac.kr