Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. yafang.li@dartmouth.edu.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. jinyoung.byun@dartmouth.edu.|Department of Genetics, Dartmouth College, Hanover, NH, USA. guoshuai.cai@dartmouth.edu.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. xiangjun.xiao@dartmouth.edu.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. Younghun.Han@dartmouth.edu.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. silenroc.olivier@gmail.com.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. jedinulos@gmail.com.|Centre for Cancer Genetic Epidemiology, Cambridge University, Cambridge, UK. jgd29@cam.ac.uk.|Centre for Cancer Genetic Epidemiology, Cambridge University, Cambridge, UK. dfe20@medscho.cam.ac.uk.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. ivan.p.gorlov@dartmouth.edu.|Rowe Program in Genetics, U.C. Davis, Davis, CA, USA. mfseldin@ucdavis.edu.|Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA. christopher.i.amos@dartmouth.edu.