Computational Biology and Machine Learning Laboratory, Center for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast BT9 7BL, UK, Institute for Bioinformatics and Translational Research, UMIT, 6060, Hall in Tyrol, Austria and Department of Computer Science, Universität der Bundeswehr München, 85577 Neubiberg, Germany Computational Biology and Machine Learning Laboratory, Center for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast BT9 7BL, UK, Institute for Bioinformatics and Translational Research, UMIT, 6060, Hall in Tyrol, Austria and Department of Computer Science, Universität der Bundeswehr München, 85577 Neubiberg, Germany.