Division of Medicine, University College London, London WC1E 6BT, UK, Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland. alan.j.medlar@helsinki.fi|Division of Medicine, University College London, London WC1E 6BT, UK, Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland. alan.j.medlar@helsinki.fi|Division of Medicine, University College London, London WC1E 6BT, UK, Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland. alan.j.medlar@helsinki.fi|Division of Medicine, University College London, London WC1E 6BT, UK, Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland. alan.j.medlar@helsinki.fi|Division of Medicine, University College London, London WC1E 6BT, UK, Institute of Biotechnology, University of Helsinki, Helsinki 00014, Finland. alan.j.medlar@helsinki.fi