Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE 19711, USA. huang@dbi.udel.edu