State Key Laboratory of Intelligent Technology and Systems, Department of Automation, Institute of Bioinformatics, Tsinghua University, Beijing 100084, Peoples Republic of China. hying99@mails.tsinghua.edu.cn|State Key Laboratory of Intelligent Technology and Systems, Department of Automation, Institute of Bioinformatics, Tsinghua University, Beijing 100084, Peoples Republic of China. hying99@mails.tsinghua.edu.cn