Medical Systems Biology, Ulm University, 89069 Ulm, Germany.|Medical Systems Biology, Ulm University, 89069 Ulm, Germany.|Medical Systems Biology, Ulm University, 89069 Ulm, Germany, Section of Oncology, Internal Medicine III, Ulm University, 89069 Ulm, Germany and.|Medical Systems Biology, Ulm University, 89069 Ulm, Germany.|Leibniz Institute on Aging-Fritz Lipmann Institute, 07745 Jena, Germany.|Medical Systems Biology, Ulm University, 89069 Ulm, Germany, Leibniz Institute on Aging-Fritz Lipmann Institute, 07745 Jena, Germany.