Department of Bioinformatics and Biochemistry, Technical University Braunschweig, Braunschweig, Germany. volker.egelhofer@univie.ac.at|Department of Bioinformatics and Biochemistry, Technical University Braunschweig, Braunschweig, Germany. volker.egelhofer@univie.ac.at|Department of Bioinformatics and Biochemistry, Technical University Braunschweig, Braunschweig, Germany. volker.egelhofer@univie.ac.at