Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 447, Houston, TX 77030-4009, USA. jefmorris@mdanderson.org|Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 447, Houston, TX 77030-4009, USA. jefmorris@mdanderson.org|Department of Biostatistics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd Unit 447, Houston, TX 77030-4009, USA. jefmorris@mdanderson.org