Bioinformatics Institute, National University of Singapore, 138671. zhuhao@bii.a-star.edu.sg|Bioinformatics Institute, National University of Singapore, 138671. zhuhao@bii.a-star.edu.sg|Bioinformatics Institute, National University of Singapore, 138671. zhuhao@bii.a-star.edu.sg|Bioinformatics Institute, National University of Singapore, 138671. zhuhao@bii.a-star.edu.sg