Joint Center for Molecular Modeling, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA. mallikav@burnham.org|Joint Center for Molecular Modeling, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA. mallikav@burnham.org|Joint Center for Molecular Modeling, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA. mallikav@burnham.org