Department of Mathematics and Statistics, American University, Washington, DC, USA.|The Jackson Laboratory, Bar Harbor, ME, USA.|Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT, USA.|Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT, USA.|Chemical and Physical Biology Graduate Program, Vanderbilt University, Nashville, TN, USA.|Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA.|Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.|Department of Cancer Biology, Vanderbilt University, Nashville, TN, USA.|Cancer Program, Roper St Francis HealthCare, Charleston, SC, USA.|Department of Medicine, University of Connecticut Health Center, Farmington, CT, USA.|Department of Molecular Biology and Biophysics, University of Connecticut Health Center, Farmington, CT, USA.|Center for Quantitative Medicine, University of Connecticut Health Center, Farmington, CT, USA.