Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw|Division of Biostatistics and Bioinformatics, National Health Research Institutes, #128, Sec. 2 Yaun-Chio-Yun Rd, Taipei 115, Taiwan. cylin@nhri.org.tw