Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Bayer Pharma AG, Müllerstr 178, 13342 Berlin, Germany. bertram.weiss@bayer.com.|Department of Pharmacology, University of California, San Diego, La Jolla, CA, USA. azambon@ucsd.edu.