Department of Bioinformatics and Computational Biology, The University of Texas, M. D. Anderson Cancer Center, Houston, TX 77030, USA. yuanji@mdanderson.org|Department of Bioinformatics and Computational Biology, The University of Texas, M. D. Anderson Cancer Center, Houston, TX 77030, USA. yuanji@mdanderson.org|Department of Bioinformatics and Computational Biology, The University of Texas, M. D. Anderson Cancer Center, Houston, TX 77030, USA. yuanji@mdanderson.org