Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, North Carolina, United States of America. paul.magwene@duke.edu|Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, North Carolina, United States of America. paul.magwene@duke.edu|Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, North Carolina, United States of America. paul.magwene@duke.edu