Department of Systems Biology, Harvard Medical School, Boston, MA, USA.|Department of Systems Biology, Harvard Medical School, Boston, MA, USA.|Department of Systems Biology, Harvard Medical School, Boston, MA, USA.|Department of Systems Biology, Harvard Medical School, Boston, MA, USA.|IRIF, Université Paris-Diderot - Paris Paris, France.|Département dinformatique de lENS (INRIA/ENS/CNRS), PSL Research University, Paris, France.|Department of Systems Biology, Harvard Medical School, Boston, MA, USA.|Department of Computational Media, UC Santa Cruz, Santa Cruz, CA, USA.|Department of Systems Biology, Harvard Medical School, Boston, MA, USA.