Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.|Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.|Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.|Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.|Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.|Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.