Department of Epidemiology and Public Health, Imperial College, St Marys Campus, Norfolk Place, London, W2 1PG, UK. m.chadeau@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, St Marys Campus, Norfolk Place, London, W2 1PG, UK. m.chadeau@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, St Marys Campus, Norfolk Place, London, W2 1PG, UK. m.chadeau@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, St Marys Campus, Norfolk Place, London, W2 1PG, UK. m.chadeau@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, St Marys Campus, Norfolk Place, London, W2 1PG, UK. m.chadeau@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, St Marys Campus, Norfolk Place, London, W2 1PG, UK. m.chadeau@imperial.ac.uk