UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Ireland. fergal.p.casey@gmail.com|UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Ireland. fergal.p.casey@gmail.com|UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Ireland. fergal.p.casey@gmail.com|UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Ireland. fergal.p.casey@gmail.com