Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.|Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.|Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.|Center for Bioimage Informatics, Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA.