Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.|Department of Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.