MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. t.beck@har.mrc.ac.uk|MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. t.beck@har.mrc.ac.uk|MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. t.beck@har.mrc.ac.uk|MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. t.beck@har.mrc.ac.uk|MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. t.beck@har.mrc.ac.uk|MRC Harwell, Harwell Science and Innovation Campus, Oxfordshire, OX11 0RD, UK. t.beck@har.mrc.ac.uk