Department of Biochemical Sciences A, Rossi Fanelli, Sapienza University, 00185 Rome, Italy.|Department of Biochemical Sciences A, Rossi Fanelli, Sapienza University, 00185 Rome, Italy.|Department of Biochemical Sciences A, Rossi Fanelli, Sapienza University, 00185 Rome, Italy.|Department of Biochemical Sciences A, Rossi Fanelli, Sapienza University, 00185 Rome, Italy.