Department of Biomolecular Sciences and Biotechnology, University of Milan, via Celoria 26, 20133 Milano, Italy. David.horner@unimi.it|Department of Biomolecular Sciences and Biotechnology, University of Milan, via Celoria 26, 20133 Milano, Italy. David.horner@unimi.it|Department of Biomolecular Sciences and Biotechnology, University of Milan, via Celoria 26, 20133 Milano, Italy. David.horner@unimi.it