School of Computer Science and Technology, Soochow University, Suzhou, Jiangsu 215006, China Department of Computational Medicine and Bioinformatics, 100 Washtenaw Avenue, Ann Arbor, MI 48109, USA.|School of Computer Science and Technology, Soochow University, Suzhou, Jiangsu 215006, China Collaborative Innovation Center of Novel Software Technology and Industrialization, Nanjing, Jiangsu, China.|Department of Computational Medicine and Bioinformatics, 100 Washtenaw Avenue, Ann Arbor, MI 48109, USA Department of Biological Chemistry, 100 Washtenaw Avenue, Ann Arbor, MI 48109, USA.