Computational Biology and Machine Learning Laboratory, Center for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Faculty of Medicine Health and Life Sciences, Queens University Belfast, BT9 7AE Belfast, UK.|Computational Biology and Machine Learning Laboratory, Center for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Faculty of Medicine Health and Life Sciences, Queens University Belfast, BT9 7AE Belfast, UK School of Mathematics and Physics, Queens University Belfast, BT7 1NN Belfast, UK.|Computational Biology and Machine Learning Laboratory, Center for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Faculty of Medicine Health and Life Sciences, Queens University Belfast, BT9 7AE Belfast, UK.|Northern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology, Queens University Belfast, BT9 7AE Belfast, UK.|Northern Ireland Molecular Pathology Laboratory, Centre for Cancer Research and Cell Biology, Queens University Belfast, BT9 7AE Belfast, UK.|Division of Biomedical Informatics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.|Department of Biomedical Computer Science and Mechatronics, UMIT, Hall in Tirol, Austria College of Computer and Control Engineering, Nankai University, Tianjin, P.R. China.|Computational Biology and Machine Learning Laboratory, Center for Cancer Research and Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Faculty of Medicine Health and Life Sciences, Queens University Belfast, BT9 7AE Belfast, UK Predictive Medicine and Analytics Lab, Department of Signal Processing, Tampere University of Technology, 33720 Tampere, Finland Institute of Biosciences and Medical Technology, 33720 Tampere, Finland.