Amino Acid Sequence|Binding Sites|Computer Simulation|Conserved Sequence|Evolution, Molecular|Genetic Variation|Models, Chemical|Models, Genetic|Models, Molecular|Molecular Sequence Data|Protein Binding|Protein Conformation|Protein-Tyrosine Kinases|Sequence Alignment|Sequence Analysis, Protein|Sequence Homology, Amino Acid|Structure-Activity Relationship