Department of Physics, Sapienza University, 00185 Rome, Italy, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark and Istituto Pasteur-Fondazione Cenci Bolognetti, 00185 Rome, Italy Department of Physics, Sapienza University, 00185 Rome, Italy, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, Lyngby, Denmark and Istituto Pasteur-Fondazione Cenci Bolognetti, 00185 Rome, Italy.