Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.|Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.|Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.|Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.|Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.|Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.|Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.