King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, Thuwal 23955-6900, Saudi Arabia.|Beijing Key Laboratory of Big Data Management and Analysis Methods, School of Information, Renmin University of China, Beijing 100872, China.|Toyota Technological Institute at Chicago, 6045 Kenwood Avenue, Chicago, IL 60637, USA Department of Human Genetics, University of Chicago, E. 58th St, Chicago, IL 60637, USA.|King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, Thuwal 23955-6900, Saudi Arabia.|King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, Thuwal 23955-6900, Saudi Arabia.