School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.|Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health Sciences, University of Manchester, Manchester, United Kingdom.|Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health Sciences, University of Manchester, Manchester, United Kingdom.|School of Physics and Astronomy, Faculty of Engineering and Physical Sciences, University of Manchester, Manchester, United Kingdom.|Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health Sciences, University of Manchester, Manchester, United Kingdom.