Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.|Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.|Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.|Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.|Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.|Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.|Department of Biosciences and Informatics, Keio University, Yokohama 161-0031, Japan.