Bioinformatics Institute, 30 Biopolis Street, Singapore 138671, Singapore. kuobin@bii.a-star.edu.sg|Bioinformatics Institute, 30 Biopolis Street, Singapore 138671, Singapore. kuobin@bii.a-star.edu.sg|Bioinformatics Institute, 30 Biopolis Street, Singapore 138671, Singapore. kuobin@bii.a-star.edu.sg