Department of Biostatistics, University of Pittsburgh, Pittsburgh, USA.|Department of Epidemiology and Biostatistics, University of Maryland, College Park, MD, USA.|Department of Biostatistics, University of Pittsburgh, Pittsburgh, USA.|Department of Biostatistics, University of Pittsburgh, Pittsburgh, USA.|Division of Pediatric Pulmonology, Allergy and Immunology, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, USA.|Division of Pediatric Pulmonology, Allergy and Immunology, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, USA.|Division of Pediatric Pulmonology, Allergy and Immunology, Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, USA.|Department of Biostatistics, University of Pittsburgh, Pittsburgh, USA.|Department of Biostatistics, University of Pittsburgh, Pittsburgh, USA.