Department of Medicine and Program in Bioinformatics and Proteomics/Genomics, Medical University of Ohio, Toledo, 43614, USA.|Department of Medicine and Program in Bioinformatics and Proteomics/Genomics, Medical University of Ohio, Toledo, 43614, USA.|Department of Medicine and Program in Bioinformatics and Proteomics/Genomics, Medical University of Ohio, Toledo, 43614, USA.