Graduate School of Biomedical Sciences, New York, NY, USA.|Icahn Institute for Genomics and Multiscale Biology, New York, NY, USA.|Sema4, a Mount Sinai venture, Stamford, CT, USA.|Mindich Child Health and Development Institute, and Departments of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.|Mindich Child Health and Development Institute, and Departments of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.|Department of Genetics, Harvard Medical School, Boston, MA, USA.|Department of Genetics, Harvard Medical School, Boston, MA, USA.|Department of Genetics, Harvard Medical School, Boston, MA, USA.|Department of Genetics, Harvard Medical School, Boston, MA, USA.|Departments of Systems Biology, Columbia University, New York, NY, USA.|Department of Pediatrics, University of Rochester Medical Center, Rochester, NY, USA.|Cardiorespiratory Unit, Great Ormond Street Hospital and University College London, London UK.|Departments of Systems Biology, Columbia University, New York, NY, USA.|Pediatrics, and Medicine, Columbia University, New York, NY, USA.|Department of Genetics, Harvard Medical School, Boston, MA, USA.|Department of Genetics, Harvard Medical School, Boston, MA, USA.|Icahn Institute for Genomics and Multiscale Biology, New York, NY, USA.|Mindich Child Health and Development Institute, and Departments of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.