Department of Molecular Biology and Biochemistry, 560 Steinhaus Hall, University of California, Irvine, California 92697-3900, USA. aroca@uci.edu|Department of Molecular Biology and Biochemistry, 560 Steinhaus Hall, University of California, Irvine, California 92697-3900, USA. aroca@uci.edu|Department of Molecular Biology and Biochemistry, 560 Steinhaus Hall, University of California, Irvine, California 92697-3900, USA. aroca@uci.edu