Informatics Institute, University of Missouri, Columbia, 65211, USA. guanlin@mail.missouri.edu|Informatics Institute, University of Missouri, Columbia, 65211, USA. guanlin@mail.missouri.edu|Informatics Institute, University of Missouri, Columbia, 65211, USA. guanlin@mail.missouri.edu|Informatics Institute, University of Missouri, Columbia, 65211, USA. guanlin@mail.missouri.edu