Theoretical Biology and Bioinformatics group, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, Utrecht, 3584CH, Utrecht, the Netherlands. l.fokkens@uu.nl|Theoretical Biology and Bioinformatics group, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, Utrecht, 3584CH, Utrecht, the Netherlands. l.fokkens@uu.nl|Theoretical Biology and Bioinformatics group, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, Utrecht, 3584CH, Utrecht, the Netherlands. l.fokkens@uu.nl|Theoretical Biology and Bioinformatics group, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, Utrecht, 3584CH, Utrecht, the Netherlands. l.fokkens@uu.nl