National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, University of Michigan, Ann Arbor, MI 48109, USA.