School of Biological and Chemical Sciences, Washington Singer Laboratories, University of Exeter, Perry Road, Exeter EX4 4QG, UK.|School of Biological and Chemical Sciences, Washington Singer Laboratories, University of Exeter, Perry Road, Exeter EX4 4QG, UK.|School of Biological and Chemical Sciences, Washington Singer Laboratories, University of Exeter, Perry Road, Exeter EX4 4QG, UK.