Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK. simon.fiddy@well.ox.ac.uk|Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK. simon.fiddy@well.ox.ac.uk|Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK. simon.fiddy@well.ox.ac.uk|Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK. simon.fiddy@well.ox.ac.uk|Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK. simon.fiddy@well.ox.ac.uk