Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G0A4, Canada.|Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G0A4, Canada.|Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G0A4, Canada.|Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G0A4, Canada.|Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G0A4, Canada.|Program in Genetics and Genome Biology, Research Institute, The Hospital for Sick Children, Toronto, Ontario, M5G0A4, Canada.