Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.|Department of Chemistry, Department of Bioinformatics and Biostatistics, Department of Pharmacology & Toxicology, Alcohol Research Center, Department of Medicine, University of Louisville and Robley Rex Louisville VAMC, Louisville, KY 40292, USA.