Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com|Merck and Co., Inc., Department of Bioinformatics, Rahway, NJ 07065, USA. jeffrey_yuan@merck.com