CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China. a.teschendorff@ucl.ac.uk.|Medical Genomics, Paul OGorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, WC1E 6BT, London, United Kingdom.|CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.|Medical Genomics, Paul OGorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, WC1E 6BT, London, United Kingdom.