Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, California, United States of America.|David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America.|Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, California, United States of America.|Institute for Quantitative and Computational Biosciences, University of California, Los Angeles, California, United States of America.