Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada. goldenberg@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada. goldenberg@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada. goldenberg@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada. goldenberg@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada. goldenberg@utoronto.ca