Medical Genetics Section, School of Molecular and Clinical Medicine, University of Edinburgh EH4 2XU UK. euan.adie@ed.ac.uk|Medical Genetics Section, School of Molecular and Clinical Medicine, University of Edinburgh EH4 2XU UK. euan.adie@ed.ac.uk|Medical Genetics Section, School of Molecular and Clinical Medicine, University of Edinburgh EH4 2XU UK. euan.adie@ed.ac.uk|Medical Genetics Section, School of Molecular and Clinical Medicine, University of Edinburgh EH4 2XU UK. euan.adie@ed.ac.uk|Medical Genetics Section, School of Molecular and Clinical Medicine, University of Edinburgh EH4 2XU UK. euan.adie@ed.ac.uk