Department of Statistics, Harvard University, Cambridge, MA, USA.|Department of Statistics, Harvard University, Cambridge, MA, USA.|Computational Health Informatics Program, Boston Childrens Hospital, Boston, MA, USA.|Computational Health Informatics Program, Boston Childrens Hospital, Boston, MA, USA.|The Synergist, Brussels, Belgium.|Computational Health Informatics Program, Boston Childrens Hospital, Boston, MA, USA.