Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. jgreid@bcm.edu.|Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. jgreid@bcm.edu.|Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. jgreid@bcm.edu.|Escuela Superior de Ingeniería Informática, Universidade de Vigo, Campus Universitario As Lagoas s/n, 32004 Ourense, Spain. riverola@uvigo.es.