Department of Biostatistics, Department of Genetics, Department of Computer Science.|Department of Genetics, Curriculum in Bioinformatics and Computational Biology, Department of Statistics, University of North Carolina, Chapel Hill, NC 27599, USA.|Department of Biostatistics, Department of Genetics, Department of Computer Science.|Division of Pediatric Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Childrens Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Department of Biostatistics, Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, PA 15224, USA and.|Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA.|Department of Biostatistics, Department of Genetics.|Department of Biostatistics, Department of Genetics, Department of Computer Science.