Bioinformatics, Conway Institute, University College Dublin, Dublin 4, Ireland. aedin.culhane@ucd.ie|Bioinformatics, Conway Institute, University College Dublin, Dublin 4, Ireland. aedin.culhane@ucd.ie|Bioinformatics, Conway Institute, University College Dublin, Dublin 4, Ireland. aedin.culhane@ucd.ie|Bioinformatics, Conway Institute, University College Dublin, Dublin 4, Ireland. aedin.culhane@ucd.ie