Bioinformatics and Systems Biology Lab, Federal University of Paraná, Curitiba, Brazil.|Bioinformatics and Systems Biology Lab, Federal University of Paraná, Curitiba, Brazil.|Canadas Michael Smith Genome Sciences Center, BC Cancer Agency, Vancouver, Canada.|Canadas Michael Smith Genome Sciences Center, BC Cancer Agency, Vancouver, Canada.|Department of Oncology and Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.|Department of Oncology and Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, United Kingdom.|Bioinformatics and Systems Biology Lab, Federal University of Paraná, Curitiba, Brazil.