Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America. cye@bioinf.ucsd.edu|Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America. cye@bioinf.ucsd.edu|Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America. cye@bioinf.ucsd.edu|Bioinformatics Program, University of California San Diego, La Jolla, California, United States of America. cye@bioinf.ucsd.edu