Center for Statistical Genetics, Department of Molecular and Human Genetics, One Baylor Plaza 700D, Baylor College of Medicine, Houston, TX 77030, USA.|Center for Statistical Genetics, Department of Molecular and Human Genetics, One Baylor Plaza 700D, Baylor College of Medicine, Houston, TX 77030, USA.|Center for Statistical Genetics, Department of Molecular and Human Genetics, One Baylor Plaza 700D, Baylor College of Medicine, Houston, TX 77030, USA.