Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore. wongwc@bii.a-star.edu.sg.|Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore. wongwc@bii.a-star.edu.sg.|Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore. wongwc@bii.a-star.edu.sg.|Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), 30 Biopolis Street, #07-01, Matrix, Singapore 138671, Singapore. wongwc@bii.a-star.edu.sg.|Bioinformatics Centre, Bose Institute, Kolkata 700054, India. zhumur@jcbose.ac.in.