Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Saarbrücken, Germany. tobias.sing@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Saarbrücken, Germany. tobias.sing@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Saarbrücken, Germany. tobias.sing@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Saarbrücken, Germany. tobias.sing@mpi-sb.mpg.de