Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, KY, USA. v0pihu01@louisville.edu|Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, KY, USA. v0pihu01@louisville.edu|Department of Bioinformatics and Biostatistics, University of Louisville, Louisville, KY, USA. v0pihu01@louisville.edu