Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.