Centre for Biochemical Engineering and Biotechnology, Institute for Cell Dynamics and Biotechnology: a Centre for Systems Biology, University of Chile, Santiago, Chile. aolivera@ing.uchile.cl|Centre for Biochemical Engineering and Biotechnology, Institute for Cell Dynamics and Biotechnology: a Centre for Systems Biology, University of Chile, Santiago, Chile. aolivera@ing.uchile.cl|Centre for Biochemical Engineering and Biotechnology, Institute for Cell Dynamics and Biotechnology: a Centre for Systems Biology, University of Chile, Santiago, Chile. aolivera@ing.uchile.cl