Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu|Delaware Biotechnology Institute, University of Delaware, Newark, DE, USA. arighi@dbi.udel.edu