Computational Biosciences Section, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830-6480, USA. xyn@ornl.gov|Computational Biosciences Section, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830-6480, USA. xyn@ornl.gov|Computational Biosciences Section, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830-6480, USA. xyn@ornl.gov|Computational Biosciences Section, Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830-6480, USA. xyn@ornl.gov