Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.|Division of Genetics, Brigham and Womens Hospital, Boston, MA 02115, USA.