School of Mathematics and Statistics, The University of Sydney, Sydney, NSW, Australia.|Melanoma Institute of Australia, Wollstonecraft, NSW, Australia.|Melanoma Institute of Australia, Wollstonecraft, NSW, Australia.|Melanoma Institute of Australia, Wollstonecraft, NSW, Australia.|Genentech Inc, South San Francisco, CA, USA.|Genentech Inc, South San Francisco, CA, USA.|Melanoma Institute of Australia, Wollstonecraft, NSW, Australia.|Melanoma Institute of Australia, Wollstonecraft, NSW, Australia.|Melanoma Institute of Australia, Wollstonecraft, NSW, Australia.|School of Mathematics and Statistics, The University of Sydney, Sydney, NSW, Australia.|School of Mathematics and Statistics, The University of Sydney, Sydney, NSW, Australia.|School of Mathematics and Statistics, The University of Sydney, Sydney, NSW, Australia.