Department of Biosystems Science and Engineering, ETH Zürich, Basel CH 4058, Switzerland.|Computing and Mathematical Sciences, California Institute of Technology, Pasadena, CA 91125, USA.|European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge CB10 1SD, UK and.|Department of Neurology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center and School of Medicine, New York, NY 10029, USA.|Department of Biosystems Science and Engineering, ETH Zürich, Basel CH 4058, Switzerland.|Department of Neurology, Icahn School of Medicine at Mount Sinai, Mount Sinai Medical Center and School of Medicine, New York, NY 10029, USA.