Structural Genomics Consortium, and Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5G 1L7, Canada.|Structural Genomics Consortium, and Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5G 1L7, Canada.|Structural Genomics Consortium, and Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5G 1L7, Canada.|Structural Genomics Consortium, and Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5G 1L7, Canada.