Departments of Biochemistry & Molecular Biology and Medical Genetics, Alberta Childrens Hospital Research Institute, University of Calgary, Calgary, Canada.|Departments of Biochemistry & Molecular Biology and Medical Genetics, Alberta Childrens Hospital Research Institute, University of Calgary, Calgary, Canada.|Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC, USA.|Departments of Biochemistry & Molecular Biology and Medical Genetics, Alberta Childrens Hospital Research Institute, University of Calgary, Calgary, Canada.|Department of Bioinformatics, Electronic and Information Engineering School, Xian Jiaotong University, Xian, China.|Departments of Biochemistry & Molecular Biology and Medical Genetics, Alberta Childrens Hospital Research Institute, University of Calgary, Calgary, Canada.