Center for Bioinformatics and Computational Biology, Applied Math & Statistics, and Scientific Computation.|Laboratory for Molecular and Computational Genomics, Department of Chemistry, Laboratory of Genetics, USA and the UW-Biotechnology Center, University of Wisconsin-Madison, WI 53706, USA.|Center for Bioinformatics and Computational Biology, Applied Math & Statistics, and Scientific Computation, Department of Computer Science, University of Maryland, College Park, MD 20742, USA and.