Global Pre-Clinical Statistics, Pfizer Global Research and Development, San Diego, CA 92121, USA. Jingjing.Ye@pfizer.com|Global Pre-Clinical Statistics, Pfizer Global Research and Development, San Diego, CA 92121, USA. Jingjing.Ye@pfizer.com|Global Pre-Clinical Statistics, Pfizer Global Research and Development, San Diego, CA 92121, USA. Jingjing.Ye@pfizer.com|Global Pre-Clinical Statistics, Pfizer Global Research and Development, San Diego, CA 92121, USA. Jingjing.Ye@pfizer.com|Global Pre-Clinical Statistics, Pfizer Global Research and Development, San Diego, CA 92121, USA. Jingjing.Ye@pfizer.com