Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu|Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu|Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu|Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu|Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu|Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu|Department of Biostatistics, University of Alabama, Birmingham, AL, USA. gpage@uab.edu