Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.|Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.|Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.|Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.