MOSAIC Group, Center of Systems Biology Dresden (CSBD), Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany. ivos@mpi-cbg.de.|MOSAIC Group, Center of Systems Biology Dresden (CSBD), Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany. ivos@mpi-cbg.de.|MOSAIC Group, Center of Systems Biology Dresden (CSBD), Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany. ivos@mpi-cbg.de.|MOSAIC Group, Center of Systems Biology Dresden (CSBD), Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany. ivos@mpi-cbg.de.|MOSAIC Group, Center of Systems Biology Dresden (CSBD), Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany. ivos@mpi-cbg.de.|MOSAIC Group, Center of Systems Biology Dresden (CSBD), Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany. ivos@mpi-cbg.de.|Center for Evolutionary Medicine and Informatics, The Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA. jieping.ye@asu.edu.