Leibniz Supercomputing Center, Garching, Department for Medical Informatics, Biometry and Epidemiology, Munich, Germany, Cambridge, MA, Dana-Farber Cancer Institute, Boston, Harvard School of Public Health, Boston, USA and City University of New York School of Public Health, Hunter College, New York, USALeibniz Supercomputing Center, Garching, Department for Medical Informatics, Biometry and Epidemiology, Munich, Germany, Cambridge, MA, Dana-Farber Cancer Institute, Boston, Harvard School of Public Health, Boston, USA and City University of New York School of Public Health, Hunter College, New York, USA.