Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan. martin@cbrc.jp|Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan. martin@cbrc.jp|Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan. martin@cbrc.jp|Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan. martin@cbrc.jp