Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Medical Research Institute (IMIM), Barcelona 08003, Spain.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.|Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.