Research Center for Genetic Medicine, Childrens National Medical Center, Washington, DC 20010, USA. jseo@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, Washington, DC 20010, USA. jseo@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, Washington, DC 20010, USA. jseo@cnmcresearch.org