Department of Medicine, Department of Pharmacology, Computational Biosciences Training Program, University of Colorado School of Medicine, Aurora, CO, USA.|Department of Medicine.|University of Colorado Cancer Center, Aurora, CO, USA and.|Department of Medicine, University of Colorado Cancer Center, Aurora, CO, USA and.|Department of Medicine, University of Colorado Cancer Center, Aurora, CO, USA and.|Department of Medicine, Department of Pharmacology, Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, CO, USA.