Department of Medicine, Section of Genetic Medicine and Center for Biomedical Informatics, the University of Chicago, Chicago, IL, USA.|Department of Medicine, Section of Genetic Medicine and Center for Biomedical Informatics, the University of Chicago, Chicago, IL, USA.|Department of Medicine, Section of Genetic Medicine and Center for Biomedical Informatics, the University of Chicago, Chicago, IL, USA.|Department of Medicine, Section of Genetic Medicine and Center for Biomedical Informatics, the University of Chicago, Chicago, IL, USA.