Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA. jhu@mdanderson.org|Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA. jhu@mdanderson.org|Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA. jhu@mdanderson.org|Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA. jhu@mdanderson.org|Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA. jhu@mdanderson.org|Department of Bioinformatics and Computational Biology, University of Texas M.D. Anderson Cancer Center, TX, USA. jhu@mdanderson.org