Department of Applied Computing, the University of Buckingham, Buckingham, MK18 1EG, UK. maysson.ibrahim@buckingham.co.uk.|Department of Applied Computing, the University of Buckingham, Buckingham, MK18 1EG, UK. sabah.jassim@buckingham.ac.uk.|The Buckingham Institute for Translational Medicine, the University of Buckingham, Buckingham, MK18 1EG, UK. mike.cawthorne@buckingham.ac.uk.|The Buckingham Institute for Translational Medicine, the University of Buckingham, Buckingham, MK18 1EG, UK. kenneth.langlands@buckingham.ac.uk.