Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu|Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu|Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu|Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu|Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu|Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu|Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA. bottomly@ohsu.edu