School of Public Health, Southwest Medical University, Luzhou, Sichuan, PR, China.|Basic Medical College of Southwest Medical University, Luzhou, Sichuan, PR, China.|Integrative Genomics Core, City of Hope National Medical Center, Duarte, CA, USA.|Key Laboratory for Aging and Regenerative Medicine, Department of Pharmacology, School of Pharmacy, Southwest Medical University, Luzhou, Sichuan, China.