Department of Computer Science, University of Rochester, Rochester, 14620, NY, USA.|Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, 77030, TX, USA.|Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, 77030, TX, USA.|Department of Biostatistics, University of Texas Health Science Center, Houston, 77030, TX, USA.|Department of Computer Science, University of Rochester, Rochester, 14620, NY, USA.|Department of Biostatistics, University of Texas Health Science Center, Houston, 77030, TX, USA. hongyu.miao@uth.tmc.edu.