Department of Information and Computer Science, College of Medicine, University of California, Irvine 92697-3425, USA.|Department of Information and Computer Science, College of Medicine, University of California, Irvine 92697-3425, USA.|Department of Information and Computer Science, College of Medicine, University of California, Irvine 92697-3425, USA.|Department of Information and Computer Science, College of Medicine, University of California, Irvine 92697-3425, USA.|Department of Information and Computer Science, College of Medicine, University of California, Irvine 92697-3425, USA.