Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA. sji@cs.odu.edu.|Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA. sji@cs.odu.edu.|Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA. sji@cs.odu.edu.|Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA. sji@cs.odu.edu.|Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA. sji@cs.odu.edu.|Department of Computer Science, Old Dominion University, Norfolk, VA 23529, USA. sji@cs.odu.edu.|Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK. ndr@ebi.ac.uk.