Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, University of Iceland, Reykjavík, Iceland, deCODE Genetics/Amgen, Reykjavík, Iceland and School of Science and Engineering, Reykjavík University, Reykjavík, Iceland Faculty of Industrial Engineering, Mechanical Engineering and Computer Science, University of Iceland, Reykjavík, Iceland, deCODE Genetics/Amgen, Reykjavík, Iceland and School of Science and Engineering, Reykjavík University, Reykjavík, Iceland.