Research Centre in Infectious Diseases, CHUL Research Centre, 2705 Laurier Blvd,, Quebec, QC G1V 4G2, Canada. martin.smith@umontreal.ca|Research Centre in Infectious Diseases, CHUL Research Centre, 2705 Laurier Blvd,, Quebec, QC G1V 4G2, Canada. martin.smith@umontreal.ca|Research Centre in Infectious Diseases, CHUL Research Centre, 2705 Laurier Blvd,, Quebec, QC G1V 4G2, Canada. martin.smith@umontreal.ca