School of Ophthalmology & Optometry and Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, P. R. China and College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, P. R. China.|College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, P. R. China.|School of Ophthalmology & Optometry and Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, P. R. China.|School of Ophthalmology & Optometry and Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, P. R. China and College of Bioinformatics Science and Technology, Harbin Medical University, Harbin 150081, P. R. China.|School of Ophthalmology & Optometry and Eye Hospital, School of Biomedical Engineering, Wenzhou Medical University, Wenzhou 325027, P. R. China.