Computational Biology Group, IDM, Faculty of Health Sciences, University of Cape Town, Anzio Road, Cape Town, South Africa. gustavo@cbio.uct.ac.za.|Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Campus Belval, 7, avenue des Hauts fourneaux, Esch/Alzette L-4362, Luxembourg. antonio.delsol@uni.lu.