Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA. vsam@mail.nih.gov|Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA. vsam@mail.nih.gov|Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA. vsam@mail.nih.gov|Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA. vsam@mail.nih.gov|Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA. vsam@mail.nih.gov|Mathematical and Statistical Computing Laboratory, DCB, CIT, NIH, DHHS, Bethesda, MD, USA. vsam@mail.nih.gov