Department of Pathology, Leiden University Medical Center, 2300RC Leiden, The Netherlands.|Channing Division of Network Medicine, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02215, USA.|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02215, USA.