Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.|MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK.|MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK.|National Heart and Lung Institute, Imperial College London, London, UK.|MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK.|MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK.|MRC Centre for Outbreak Analysis and Modelling, Imperial College London, London, UK.