European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Cambridge, CB10 1SD, UK, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark, Translational Research Laboratory, Breast Cancer Unit, Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), Gran via 199, LHospitalet del Llobregat, Barcelona 08908, Catalonia, Spain and Biomedical Research Institute of Girona, Girona 17007, Catalonia, Spain.