Institute of Molecular Medicine and Cell Research, University of Freiburg, D-79104 Freiburg, Germany. oliver.schilling@mol-med.uni-freiburg.de.|Institute of Molecular Medicine and Cell Research, University of Freiburg, D-79104 Freiburg, Germany. oliver.schilling@mol-med.uni-freiburg.de.|Helsinki Institute for Information Technology HIIT, Department of Information and Computer Science, Aalto University, 00076 Espoo, Finland. samuel.kaski@aalto.fi.