Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia. schroeder@wehi.edu.au.|Institut für Informatik, Johannes Gutenberg Universität Mainz, Mainz, Germany.|Institut für Informatik, Johannes Gutenberg Universität Mainz, Mainz, Germany.|Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC, 3052, Australia. papenfuss@wehi.edu.au.