Bioinformatics, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Ian.Jeffery@ucd.ie|Bioinformatics, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Ian.Jeffery@ucd.ie|Bioinformatics, Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland. Ian.Jeffery@ucd.ie