Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America.|California Institute for Quantitative Biosciences, University of California, Berkeley, California, United States of America.|Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America.|Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America.|Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America.|Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin, United States of America.|Department of Statistics, University of Wisconsin, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, University of Wisconsin, Madison, Wisconsin, United States of America.