Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York, 14642, USA.|Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, 90089, USA.|Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA and.|Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, 90089, USA.|Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA and.|Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA and.