Department of Biomolecular Engineering, University of California at Santa Cruz, Santa Cruz, CA 95064, USA. bort@soe.ucsc.edu|Department of Biomolecular Engineering, University of California at Santa Cruz, Santa Cruz, CA 95064, USA. bort@soe.ucsc.edu|Department of Biomolecular Engineering, University of California at Santa Cruz, Santa Cruz, CA 95064, USA. bort@soe.ucsc.edu