Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, Saarbrücken D-66123, Germany. sommer@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, Saarbrücken D-66123, Germany. sommer@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, Saarbrücken D-66123, Germany. sommer@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, Saarbrücken D-66123, Germany. sommer@mpi-sb.mpg.de|Department of Computational Biology and Applied Algorithmics, Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, Saarbrücken D-66123, Germany. sommer@mpi-sb.mpg.de