Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, 115, Taiwan. hsinchou@ibms.sinica.edu.tw|Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, 115, Taiwan. hsinchou@ibms.sinica.edu.tw|Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, 115, Taiwan. hsinchou@ibms.sinica.edu.tw|Institute of Biomedical Sciences, Academia Sinica, Nankang, Taipei, 115, Taiwan. hsinchou@ibms.sinica.edu.tw