Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany. christoph.dieterich@molgen.mpg.de|Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany. christoph.dieterich@molgen.mpg.de|Computational Molecular Biology, Max-Planck-Institute for Molecular Genetics, Berlin, Germany. christoph.dieterich@molgen.mpg.de