Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America.|Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, United States of America, Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado, United States of America, Molecular Oncology Program, University of Colorado Cancer Center, Aurora, Colorado, United States of America.|Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, and Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America.