Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.|Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.|Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.|Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.|Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.|Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.|Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24061, USA.