Max Planck Research Group for Computational Genomics and Epidemiology, Max Planck Institute for Informatics, University Campus E1 4, 66123 Saarbrücken, Germany.|Max Planck Research Group for Computational Genomics and Epidemiology, Max Planck Institute for Informatics, University Campus E1 4, 66123 Saarbrücken, Germany.|Max Planck Research Group for Computational Genomics and Epidemiology, Max Planck Institute for Informatics, University Campus E1 4, 66123 Saarbrücken, Germany.