Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 135 Cannon St, Charleston, SC 29425, USA.|Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 135 Cannon St, Charleston, SC 29425, USA.|Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 135 Cannon St, Charleston, SC 29425, USA.|Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 135 Cannon St, Charleston, SC 29425, USA.