UCL Genetics Institute, University College London, London WC1E 6BT, UK.|Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.|UCL Cancer Institute, University College London, London WC1E 6DD, UK.|RP Fighting Blindness, PO Box 350, Buckingham, MK18 1GZ, UK.|Institute of Ophthalmology, University College London, London EC1V 9EL, UK.|Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, London E1 2AT, UK.|Barts and The London School of Medicine and Dentistry, Blizard Institute, Queen Mary University of London, London E1 2AT, UK.|UCL Genetics Institute, University College London, London WC1E 6BT, UK.|UCL Genetics Institute, University College London, London WC1E 6BT, UK.|Institute of Ophthalmology, University College London, London EC1V 9EL, UK.|Institute of Ophthalmology, University College London, London EC1V 9EL, UK.|Department of Haematology, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0PT, UK.|Barts and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, John Vane Building, Charterhouse Square, London EC1M 6BQ, UK.|Computer Science Department, University College London, London WC1E 6BT, UK.|Computer Science Department, University College London, London WC1E 6BT, UK.|Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.|Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.|Leeds Institute of Biomedical and Clinical Sciences, University of Leeds, St Jamess University Hospital, Leeds LS9 7TF, UK.|Oxford Eye Hospital, John Radcliffe Hospital, Oxford OX3 9DU, UK.|Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester M13 9WL, UK.|Institute of Ophthalmology, University College London, London EC1V 9EL, UK.|Institute of Ophthalmology, University College London, London EC1V 9EL, UK.|Institute of Ophthalmology, University College London, London EC1V 9EL, UK.|UCL Genetics Institute, University College London, London WC1E 6BT, UK.