Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada. betel@cbio.mskcc.org|Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada. betel@cbio.mskcc.org|Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada. betel@cbio.mskcc.org|Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada. betel@cbio.mskcc.org|Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada. betel@cbio.mskcc.org|Samuel Lunenfeld Research Institute, Mt. Sinai Hospital, Toronto, Ontario, Canada. betel@cbio.mskcc.org