Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK. es505@cam.ac.uk|Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK. es505@cam.ac.uk|Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK. es505@cam.ac.uk|Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge, UK. es505@cam.ac.uk