Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA.|Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA.|Vanderbilt Genetics Institute, Nashville, TN, USA.|Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.|Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA.