Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520, USA. shuangge.ma@yale.edu|Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520, USA. shuangge.ma@yale.edu|Department of Epidemiology and Public Health, Yale University, New Haven, CT 06520, USA. shuangge.ma@yale.edu