The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. julian.gingold@mssm.edu.|Program in Applied Mathematics, Yale University, New Haven, CT, 06511, USA. ed.s.coakley@gmail.com.|The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. sujiepkubio@gmail.com.|The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. dung-fang.lee@mssm.edu.|Integrated Screening Core, Experimental Therapeutics Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. wingshan.lau@mssm.edu.|The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. hongwei.zhou@mssm.edu.|The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. dan@felsenfeld.com.|The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. christoph.schaniel@mssm.edu.|The Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ihor.lemischka@mssm.edu.