School of Electronics and Computer Science, University of Southampton, Southampton, UK.|Department of Mathematical Informatics, Graduate School of Information Science and Technology, The University of Tokyo, Tokyo, Japan and.|Department of Mathematical Informatics, Graduate School of Information Science and Technology, The University of Tokyo, Tokyo, Japan and.|Faculty of Medicine, Southampton General Hospital, University of Southampton, Southampton, UK.|Faculty of Medicine, Southampton General Hospital, University of Southampton, Southampton, UK.|School of Electronics and Computer Science, University of Southampton, Southampton, UK.