Telethon Institute of Genetics and Medicine, Via P. Castellino 111, 80131 Naples, Interactive SRL, Via Fratelli Bisogno 5, 83100 Avellino, Dip. di Studi Aziendali e Quantitativi Università degli studi di Napoli Parthenope, Via Generale Parisi 13, 80132 Naples, Institute for High-Performance Computing - ICAR - CNR, Via P. Castellino 111, 80131 Naples and Department of Electrical Engineering and Information Technology, University of Naples Federico II, Via Claudio 21, 80125 Naples, Italy.