Department of Biostatistics and Applied Mathematics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 447, Houston, TX 77030-4009, USA.|Department of Biostatistics and Applied Mathematics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 447, Houston, TX 77030-4009, USA.|Department of Biostatistics and Applied Mathematics, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Box 447, Houston, TX 77030-4009, USA.