Department of Biostatistics and Computational Biology, University of Rochester, 265 Crittenden Blvd, Rochester, 14642, NY, USA. mccallm@gmail.com.|Department of Pathology, The Johns Hopkins University, 720 Rutland Ave, Baltimore, 21205, MD, USA.|Biology Department, The Johns Hopkins University, 3400 N Charles St, Baltimore, 21218, MD, USA.|Genetic Resources Core Facility, The Johns Hopkins University, 600 N Wolfe St, Baltimore, 21287, MD, USA.|Department of Molecular and Comparative Pathobiology, The Johns Hopkins University, 733 N Broadway, Baltimore, 21205, MD, USA.|Department of Molecular and Comparative Pathobiology, The Johns Hopkins University, 733 N Broadway, Baltimore, 21205, MD, USA.|Department of Pathology, The Johns Hopkins University, 720 Rutland Ave, Baltimore, 21205, MD, USA.