Department of Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands, Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.|Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, United States of America, California Institute for Quantitative Biosciences, San Francisco, California, United States of America.|Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, United States of America, California Institute for Quantitative Biosciences, San Francisco, California, United States of America, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.|Manchester Institute of Biotechnology, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.|Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, California, United States of America, California Institute for Quantitative Biosciences, San Francisco, California, United States of America.