Center for Biomedical Informatics and Section of Genetic Medicine of Department of Medicine, Institute for Translational Medicine, and Ludwig Center for Metastasis Research, Cancer Research Center, University of Chicago, Chicago, IL 60637, USA. lussier@uchicago.edu|Center for Biomedical Informatics and Section of Genetic Medicine of Department of Medicine, Institute for Translational Medicine, and Ludwig Center for Metastasis Research, Cancer Research Center, University of Chicago, Chicago, IL 60637, USA. lussier@uchicago.edu