Mines ParisTech, Centre for Computational Biology, 35 Rue Saint-Honoré, F-77305 Fontainebleau Cedex, France.|Mines ParisTech, Centre for Computational Biology, 35 Rue Saint-Honoré, F-77305 Fontainebleau Cedex, France.|Mines ParisTech, Centre for Computational Biology, 35 Rue Saint-Honoré, F-77305 Fontainebleau Cedex, France.