Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. g39528010@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. g39528010@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. g39528010@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. g39528010@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. g39528010@ym.edu.tw