Department of Mathematical Sciences, University of Texas at Dallas, Richardson, TX, USA.|Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.|Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.|Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.|Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.