Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA.|Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA.|Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA.|Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA.|Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA.