Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.|Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill, NC 27599, USA.