Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com|Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com|Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com|Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com|Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com|Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com|Department of Biostatistics, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. parkyuhyun@gmail.com