Department of Computer Science, Xiamen University, Xiamen, Fujian, China.|Department of Computer Science, Xiamen University, Xiamen, Fujian, China.|Department of Chemistry and Biochemistry, Ohio University, Athens, OH, United States of America.|Department of Computer Science, Xiamen University, Xiamen, Fujian, China.|Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, United States of America.|Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America.