Department of Medicine, University of California San Diego, San Diego, United States of America.|Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, United States of America.|Department of Medicine, University of California San Diego, San Diego, United States of America.|Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, United States of America.|Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, United States of America.|School of Computational Science and Engineering, Georgia Institute of Technology, Atlanta, United States of America.|Department of Medicine, University of California San Diego, San Diego, United States of America.|Department of Medicine, University of California San Diego, San Diego, United States of America.