Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.|Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, Korea.|Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, Korea.|Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.|SCH Biomedical Informatics Research Unit, Soonchunhyang University Hospital, Seoul, Korea.|Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, Korea.