Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Waitemata District Health Board, North Shore Hospital, Auckland 0622, New Zealand, National Space Biomedical Research Institute, Houston, TX 77030-1402, USA, Cleveland Clinic Foundation, Cleveland, OH 44195, USA and Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.