Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana-Champaign, Illinois, United States of America.|Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle, Washington, United States of America.|Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle, Washington, United States of America.|Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle, Washington, United States of America.|Institute for Systems Biology, Seattle, Washington, United States of America.|Center for Infectious Disease Research, formerly Seattle Biomedical Research Institute, Seattle, Washington, United States of America.|Department of Chemical and Biomolecular Engineering, University of Illinois, Urbana-Champaign, Illinois, United States of America.