Eagle Genomics Ltd, The Biodata Innovation Centre, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1DR, UK.|Systems Biology Ireland, University College Dublin, Belfield, Dublin 4, Ireland.|Mosaiques Diagnostics GmbH, Hanover, Germany.|Eagle Genomics Ltd, The Biodata Innovation Centre, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1DR, UK.|Systems Biology Ireland, University College Dublin, Belfield, Dublin 4, Ireland.|Institut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institute of Cardiovascular and Metabolic Disease, Toulouse, France.|Mosaiques Diagnostics GmbH, Hanover, Germany. harald.mischak@glasgow.ac.uk.|Mosaiques Diagnostics GmbH, Hanover, Germany.