Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Childrens Hospital, Genoa, Italy. stefanoparodi@ospedale-gaslini.ge.it|Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Childrens Hospital, Genoa, Italy. stefanoparodi@ospedale-gaslini.ge.it|Epidemiology and Biostatistics Section, Scientific Directorate, G. Gaslini Childrens Hospital, Genoa, Italy. stefanoparodi@ospedale-gaslini.ge.it