Centre for Systems Biology, The University of Birmingham, Edgbaston, Birmingham, UK. hmp166@bham.ac.uk <hmp166@bham.ac.uk>|Centre for Systems Biology, The University of Birmingham, Edgbaston, Birmingham, UK. hmp166@bham.ac.uk <hmp166@bham.ac.uk>|Centre for Systems Biology, The University of Birmingham, Edgbaston, Birmingham, UK. hmp166@bham.ac.uk <hmp166@bham.ac.uk>|Centre for Systems Biology, The University of Birmingham, Edgbaston, Birmingham, UK. hmp166@bham.ac.uk <hmp166@bham.ac.uk>