Faculty of Science and Engineering, Manchester Institute of Biotechnology, University of Manchester, Manchester M1?7DN, UK.|Department of Electrical Engineering and Electronics, University of Liverpool, Liverpool L69?3GJ, UK.|Department of Social Science Research Methods, Radboud University Nijmegen, Nijmegen 6525 GD, Netherlands.|Institute for Computing and Information Sciences, Radboud University Nijmegen, Nijmegen 6525 EC, Netherlands.|Harvard School of Public Health, Dana-Farber Cancer Institute, Boston, MA 02115, USA.|Faculty of Science and Engineering, Manchester Institute of Biotechnology, University of Manchester, Manchester M1?7DN, UK.