MRC Clinical Sciences Centre, Imperial College London, W12 0NN, UK.|MRC Clinical Sciences Centre, Imperial College London, W12 0NN, UK.|MRC Clinical Sciences Centre, Imperial College London, W12 0NN, UK.|MRC Clinical Sciences Centre, Imperial College London, W12 0NN, UK.|MRC Clinical Sciences Centre, Imperial College London, W12 0NN, UK.|MRC Clinical Sciences Centre, Imperial College London, W12 0NN, UK.