CABDyN Complexity Centre, Saxc3xafd Business School, University of Oxford, Oxford OX1 1HP, UK.|CABDyN Complexity Centre, Saxc3xafd Business School, University of Oxford, Oxford OX1 1HP, UK.|e-Therapeutics plc, Long Hanborough, OX29 8LN, UK.|Department of Statistics, University of Oxford, Oxford, UK.|CABDyN Complexity Centre, Saxc3xafd Business School, University of Oxford, Oxford OX1xe2x80x891HP, UK.