Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast, Belfast, UK.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast, Belfast, UK.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast, Belfast, UK. P.Hamilton@qub.ac.uk.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast, Belfast, UK. s.zhang@qub.ac.uk.