Department of Statistics, The Pennsylvania State University, University Park, PA, 16802, USA. ywl5222@psu.edu.|Department of Statistics, The Pennsylvania State University, University Park, PA, 16802, USA. chiaro@stat.psu.edu.|Bioinformatics Institute, School of Biological Sciences, University of Auckland, Auckland, 1142, New Zealand. h.ross@auckland.ac.nz.|Department of Computer Science and Engineering, The Pennsylvania State University, University Park, PA, 16802, USA. raunaq@psu.edu.|Department of Biology, The Pennsylvania State University, University Park, PA, 16802, USA. Daniel.Elleder@img.cas.cz.|Department of Biology, The Pennsylvania State University, University Park, PA, 16802, USA. mposs@bx.psu.edu.