Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, Essen, 45147, Germany.|Life Sciences, Centrum Wiskunde & Informatica (CWI), Amsterdam 1098 XG, The Netherlands Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.|Genome Informatics, Institute of Human Genetics, University of Duisburg-Essen, Essen, 45147, Germany.