Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Level 3, Wernher and Beit North, Private Bag, Rondebosch, 7700, Anzio road, Observatory Cape Town, South Africa.|Department of Psychiatry and Mental Health, University of Cape Town, Observatory, 7925, Cape Town, South Africa.|Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Private Bag, Rondebosch, 7700, Cape Town, South Africa.|Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Private Bag, Rondebosch, 7700, Cape Town, South Africa.|Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Private Bag, Rondebosch, 7700, Cape Town, South Africa, African Institute for Mathematical Sciences, 7945 Muizenberg, Cape Town, South Africa and Computational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Medical School, Anzio Road, Observatory, 7925, Cape Town, South Africa.