Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Department and Institute of Industrial Engineering and Management, Minghsin University of Science and Technology, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.|Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu 300, Taiwan.