Globe View, London, EC4V 3PP, UK.|UCL Cancer Institute, University College London, London WC1E 6DD, UK.|Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.|Nuffield Department of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.|Computer Science Department.|Computer Science Department.|UCL Genetics Institute, University College London, London WC1E 6BT, UK.