Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. filho@molgen.mpg.de|Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. filho@molgen.mpg.de|Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. filho@molgen.mpg.de|Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. filho@molgen.mpg.de