Pacific Biosciences, Inc., Menlo Park, CA 94025, USA.|Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA.|Pacific Biosciences, Inc., Menlo Park, CA 94025, USA.|Center for Biomolecular Science and Engineering, University of California, Santa Cruz, CA 95064, USA.