Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China. wellgoo@gmail.com|Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China. wellgoo@gmail.com|Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China. wellgoo@gmail.com|Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing 100084, China. wellgoo@gmail.com