Center for Computational Biology, The University of Kansas, Lawrence, KS, 66047, USA. tatsiana.bylund@gmail.com.|Center for Computational Biology, The University of Kansas, Lawrence, KS, 66047, USA. aruvinsky@yahoo.com.|Center for Computational Biology, The University of Kansas, Lawrence, KS, 66047, USA. deepkumar1983@gmail.com.|United Institute of Informatics Problems, National Academy of Sciences, 220012, Minsk, Belarus. tuzikov@newman.bas-net.by.|Center for Computational Biology, The University of Kansas, Lawrence, KS, 66047, USA. pkundro@ku.edu.|Center for Computational Biology, The University of Kansas, Lawrence, KS, 66047, USA. vakser@ku.edu.