Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany.|Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany.|Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany.|Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany.|Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany.|Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany Department of Computer Science, University of Freiburg, Georges-Köhler-Allee 106, 79110 Freiburg, Germany, Department of Biology, University of Copenhagen, Archaea Centre, Ole Maaloes Vej 5, DK2200 Copenhagen, Denmark and BIOSS Centre for Biological Signalling Studies, Cluster of Excellence, University of Freiburg, Germany.