CUBIC & North-East Structural Genomics Consortium, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA. yanay.ofran@columbia.edu|CUBIC & North-East Structural Genomics Consortium, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA. yanay.ofran@columbia.edu