Program in Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. bucciv@mskcc.org|Program in Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. bucciv@mskcc.org|Program in Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. bucciv@mskcc.org|Program in Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA. bucciv@mskcc.org