Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. huangfei@iu.edu.|Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. cjoldfie@umail.iu.edu.|Department of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, Florida, USA. binxue@usf.edu.|Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. hsu20@iu.edu.|Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. mengj@iupui.edu.|Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. liuxiaowencs@gmail.com.|Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. shenli@iu.edu.|Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA. promero@wisc.edu.|Department of Molecular Medicine, University of South Florida, Tampa, Florida, USA. vuversky@health.usf.edu.|Center for Computational Biology and Bioinformatics, Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA. kedunker@iupui.edu.