Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.|Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.|Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.|Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.|Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.|Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.|Institute of Computational Biology, Helmholtz Center Munich, 85764 Neuherberg, Germany. fabian.theis@helmholtz-muenchen.de.