Department of Biostatistics and Medical Informatics,University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706, USA. joebock@biostat.wisc.edu|Department of Biostatistics and Medical Informatics,University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706, USA. joebock@biostat.wisc.edu|Department of Biostatistics and Medical Informatics,University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706, USA. joebock@biostat.wisc.edu|Department of Biostatistics and Medical Informatics,University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706, USA. joebock@biostat.wisc.edu|Department of Biostatistics and Medical Informatics,University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706, USA. joebock@biostat.wisc.edu