Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USADepartment of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.|Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.|Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.|Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.|Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.|Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.|Department of Information Science, School of Mathematical Sciences and LMAM, Peking University, Beijing, 100871, China and NCI Center for Modeling Cancer Development, Department of Systems Medicine and Bioengineering, Houston Methodist Hospital Research Institute, Weill Cornell Medical College of Cornell University, Houston, TX 77030, USA.