Institute of Cellular Medicine, Ageing Research Laboratories, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom.|MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), United Kingdom.|MRC/Arthritis Research UK Centre for Musculoskeletal Ageing (CIMA), United Kingdom.|Institute of Cellular Medicine, Ageing Research Laboratories, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom.