Department of Information and Computer Science, Institute for Genomics and Bioinformatics, University of California, Irvine 92697-3425, USA. baisnee@ics.uci.edu|Department of Information and Computer Science, Institute for Genomics and Bioinformatics, University of California, Irvine 92697-3425, USA. baisnee@ics.uci.edu|Department of Information and Computer Science, Institute for Genomics and Bioinformatics, University of California, Irvine 92697-3425, USA. baisnee@ics.uci.edu