Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.|Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.|Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.|Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.|Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.|Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.|Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.