Bio-Innovation, Sanofi Global Biotherapeutics, 38 Sidney Street, Cambridge, MA, 02139, USA. hong.liu@sanofi.com.|Bio-Innovation, Sanofi Global Biotherapeutics, 38 Sidney Street, Cambridge, MA, 02139, USA.|Bioinformatics Program, Northeastern University, 360 Huntington Avenue, Boston, MA, 02115, USA.|Bio-Innovation, Sanofi Global Biotherapeutics, 38 Sidney Street, Cambridge, MA, 02139, USA.|Bio-Innovation, Sanofi Global Biotherapeutics, 38 Sidney Street, Cambridge, MA, 02139, USA.