Department of Computer Science, University of Toronto, Toronto M5S 2E4, Centre for Computational Medicine and Genetics and Genome Biology, Hospital for Sick Children, Toronto M5G 1L7, Canada.|Department of Computer Science, University of Toronto, Toronto M5S 2E4, Centre for Computational Medicine and Genetics and Genome Biology, Hospital for Sick Children, Toronto M5G 1L7, Canada.|Department of Computer Science, University of Toronto, Toronto M5S 2E4, Centre for Computational Medicine and Genetics and Genome Biology, Hospital for Sick Children, Toronto M5G 1L7, CanadaDepartment of Computer Science, University of Toronto, Toronto M5S 2E4, Centre for Computational Medicine and Genetics and Genome Biology, Hospital for Sick Children, Toronto M5G 1L7, CanadaDepartment of Computer Science, University of Toronto, Toronto M5S 2E4, Centre for Computational Medicine and Genetics and Genome Biology, Hospital for Sick Children, Toronto M5G 1L7, Canada.