Bio Systems Analysis Group, Department of Mathematics and Computer Science and Jena Centre for Bioinformatics, Friedrich Schiller University Jena, 07743 Jena, Germany, Mathematics Department, University of British Columbia, Kelowna, BC V1V 1V7, Canada, Instituto de Filosofía y Ciencias de la Complejidad - IFICC, Los Alerces 3024 Ñuñoa, Santiago, Chile, Center Leo Apostel, Vrije Universiteit Brussel, B-1160 Brussels, Belgium, Umm Al-Qura University, 1109 Makkah Al-Mukarramah and Al-Qunfudah Center for Scientific Research (QCSR), 21912 Al-Qunfudah, Kingdom of Saudi Arabia.