Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan 350, Taiwan.|Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan 350, Taiwan.|Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan 350, Taiwan.|Division of Biostatistics and Bioinformatics, National Health Research Institutes, Zhunan 350, Taiwan.