Algorithms|Biological Evolution|Computational Biology|Computer Simulation|Evolution, Molecular|Gene Deletion|Likelihood Functions|Markov Chains|Models, Biological|Models, Genetic|Models, Statistical|Models, Theoretical|Molecular Sequence Data|Mutation|Probability|Protein Conformation|Protein Structure, Tertiary|RNA|RNA, Messenger|Sequence Analysis, DNA|Sequence Analysis, Protein|Sequence Analysis, RNA|Software|Time Factors