Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. olshena@biostat.ucsf.edu|Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. olshena@biostat.ucsf.edu|Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. olshena@biostat.ucsf.edu|Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. olshena@biostat.ucsf.edu|Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. olshena@biostat.ucsf.edu|Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA. olshena@biostat.ucsf.edu