Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA, Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA, Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA,Center for Human Genetic Variation, Duke University, Durham, NC, USA, School of Computer Science and Technology, Harbin Institute of Technology, Harbin, China and Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.