Department of Genetics, Rosetta Inpharmatics Merck, Seattle, Washington, United States of America. manikandan_narayanan@merck.com|Department of Genetics, Rosetta Inpharmatics Merck, Seattle, Washington, United States of America. manikandan_narayanan@merck.com|Department of Genetics, Rosetta Inpharmatics Merck, Seattle, Washington, United States of America. manikandan_narayanan@merck.com|Department of Genetics, Rosetta Inpharmatics Merck, Seattle, Washington, United States of America. manikandan_narayanan@merck.com