Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. mceachin@umich.edu|Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. mceachin@umich.edu|Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. mceachin@umich.edu|Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. mceachin@umich.edu|Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. mceachin@umich.edu|Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48105, USA. mceachin@umich.edu