School of Biomedical Sciences, Medical and Dental University, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan. hasegawa@bioinfo.tmd.ac.jp|School of Biomedical Sciences, Medical and Dental University, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan. hasegawa@bioinfo.tmd.ac.jp|School of Biomedical Sciences, Medical and Dental University, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan. hasegawa@bioinfo.tmd.ac.jp|School of Biomedical Sciences, Medical and Dental University, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan. hasegawa@bioinfo.tmd.ac.jp|School of Biomedical Sciences, Medical and Dental University, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan. hasegawa@bioinfo.tmd.ac.jp|School of Biomedical Sciences, Medical and Dental University, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan. hasegawa@bioinfo.tmd.ac.jp