Program of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA. rnishiha@hsph.harvard.edu.|Channing Division of Network Medicine, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.|Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.|Program of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.|Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.|Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.|Channing Division of Network Medicine, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Channing Division of Network Medicine, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.|Program of MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA. shuji_ogino@dfci.harvard.edu.|Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. onnela@hsph.harvard.edu.