Department of Biostatistics, Harvard School of Public Health, 677 Huntington Avenue, SPH2, 4th floor, Boston, MA 02115, USA, Department of Statistics, University of Connecticut, 215 Glenbrook Road, Storrs, CT 06269, USA, NIEHS, Epidemiology Branch, MD A3-05, PO Box 12233, Research Triangle Park, NC 27709, USA, Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Suite 1400 Chicago, IL 60611, USA, Department of Environmental Health and Department of Epidemiology, Harvard School of Public Health, 401 Park Drive, Landmark Ctr Room 415E, Boston, MA 02215, USA.