Centre for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Rome, Italy. gabriele.ausiello@uniroma2.it|Centre for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Rome, Italy. gabriele.ausiello@uniroma2.it|Centre for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Rome, Italy. gabriele.ausiello@uniroma2.it|Centre for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Rome, Italy. gabriele.ausiello@uniroma2.it