School of Physics and Key Laboratory of Molecular Biophysics of the Ministry of Education, Huazhong University of Science and Technology, Wuhan, Hubei, China.|Center for Computational Biology and Department of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, United States of America.|Center for Computational Biology and Department of Molecular Biosciences, The University of Kansas, Lawrence, Kansas, United States of America.|School of Physics and Key Laboratory of Molecular Biophysics of the Ministry of Education, Huazhong University of Science and Technology, Wuhan, Hubei, China.