Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA.|Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA.|Department of Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA.|Department of Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.