Analytic and Translational Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, MA 02114, USA.|Analytic and Translational Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, MA 02114, USA.|Analytic and Translational Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, MA 02114, USA.|Analytic and Translational Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, MA 02114, USA.