Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Department of Public Health, University of Helsinki, Helsinki, Finland.|Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.|National Institute for Health and Welfare (THL), Helsinki, Finland and.|National Institute for Health and Welfare (THL), Helsinki, Finland and.|Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Department of Public Health, University of Helsinki, Helsinki, Finland, Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, UK.|Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.