National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.|National Center for Integrative Biomedical Informatics, Center for Computational Medicine and Biology, University of Michigan, Ann Arbor, MI 48109, USA.