School of Information Science and Technology, Xiamen University, Xiamen, Fujian 361005, China. gl8008@163.com.|School of Information Science and Technology, Xiamen University, Xiamen, Fujian 361005, China. gl8008@163.com.|School of Information Science and Technology, Xiamen University, Xiamen, Fujian 361005, China. gl8008@163.com.|School of Information Science and Technology, Xiamen University, Xiamen, Fujian 361005, China. gl8008@163.com.|Department of Bioinformatics and Computational Biology, The University of Texas M,D, Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA. kchen3@mdanderson.org.