IRCCS AOU San Martino IST, Genoa, I-16132, Italy. paolo.romano@hsanmartino.it.|University of Bielefeld, Bielefeld, D-33615, Germany.|Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, D-06466, Germany.|Institute for Biomedical Technology - National Research Council, Bari, I-70126, Italy.