Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.|Department of Medicine, Vanderbilt University, Nashville, TN 37232-0275, USA.