Bioinformatics Research Department, bioMerieux, Marcy Letoile 69280, France, LBBE, UMR CNRS 5558 University Lyon 1, Villeurbanne F-69622, France.|Bioinformatics Research Department, bioMerieux, Marcy Letoile 69280, France.|Biomathematics System Development, bioMerieux, Marcy Letoile 69280, France.|Bioinformatics Research Department, bioMerieux, Marcy Letoile 69280, France.