Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2WD, UK. mxf793@bham.ac.uk.|Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2WD, UK. c.m.mcgrath@bham.ac.uk.|Rheumatology Research Group, Centre for Translational Inflammation Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2WD, UK. s.p.young@bham.ac.uk.