Interdisciplinary Bioinformatics and Systems Biology Program, University of California San Diego, La Jolla, California, United States of America.|Department of Medicine, University of California San Diego, La Jolla, California, United States of America.|Department of Medicine, University of California San Diego, La Jolla, California, United States of America.|Department of Medicine, University of California San Diego, La Jolla, California, United States of America.|Department of Pathology, University of California San Diego, La Jolla, California, United States of America, San Diego Veterans Affairs Healthcare System, San Diego, California, United States of America.|The Scripps Research Institute, La Jolla, California, United States of America, Ragon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, United States of America.|The Scripps Research Institute, La Jolla, California, United States of America.|Department of Medicine, University of California San Diego, La Jolla, California, United States of America, San Diego Veterans Affairs Healthcare System, San Diego, California, United States of America.|Department of Medicine, University of California San Diego, La Jolla, California, United States of America.