Department of Computer Science, Xiamen University, Xiamen, China.|Department of Computer Science, Xiamen University, Xiamen, China.|Department of Computer Science, Xiamen University, Xiamen, China.|Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.|Computational Structural Biology Section, Basic Science Program, Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, USA.|Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.