Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.|Department of Biostatistics and Clinical Research, CHU de Caen, Caen F-14000, France. anndo.pham@gmail.com.