Computational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.|Department of Biological Sciences and Computational Biology Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.|Ontario Institute for Cancer Research, Toronto, Canada.|EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.|School of Computer Science and Engineering, University of New South Wales, Sydney, Australia.|EMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.|School of Interdisciplinary Informatics, University of Nebraska at Omaha, Omaha, Nebraska, United States of America.|Department of Biology, Georgetown University, Washington, DC, United States of America.|Department of Genetics, University of Cambridge, Cambridge, United Kingdom.|Saint Vincent College, Latrobe, Pennsylvania, United States of America.|Department of Computer Science and Department of Bioengineering, University of Illinois, Urbana-Champaign, Champaign, United States of America.|School of Electrical Engineering and Computer Science, Ohio University, Athens, Ohio, United States of America.