Division of Genetics, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.|Division of Genetics, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.|Division of Genetics, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.|Division of Genetics, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.