Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Departments of Computer Science and of Life Sciences, Sorbonne Université (SU) / UPMC, Paris, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Department of Biology and of Computer Science, Univ. Paris-Sud, Université Paris-Saclay (UPSay), Orsay, France.|Unit of Structural Dynamics of Macromolecules, CNRS, Institut Pasteur, Paris, France.|Institute for Integrative Biology of the Cell (I2BC), IBITECS, CEA, CNRS, Univ. Paris-Sud, UPSay, Gif-sur-Yvette cedex, France.|AMIBio team, Laboratoire dinformatique de lÉcole polytechnique (LIX, UMR 7161) / Inria Saclay, UPSay, Palaiseau, France.|Laboratoire de Biochimie Théorique, UPR 9080 CNRS Institut de Biologie Physico-Chimique, Paris, France.|Sorbonne Université / UPMC, CNRS, IBPS, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), UMR 7238, Paris, France.|LRI, Univ. Paris-Sud, CNRS, UPSay, Orsay, France.|Sorbonne Université / UPMC, Univ. Antilles, Univ. Nice Sophia Antipolis, CNRS, Evolution Paris Seine - Institut de Biologie Paris Seine (EPS - IBPS), Paris, France.|Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, UPSay, Gif-sur-Yvette cedex, France.|Sorbonne Université / UPMC, CNRS, IBPS, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), UMR 7238, Paris, France.|Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, UPSay, Gif-sur-Yvette cedex, France.|Sorbonne Université / UPMC, CNRS, IBPS, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), UMR 7238, Paris, France.|Department of Structural Biology and CheImistry (CNRS UMR3528) - Center of Bioinformatics, Biostatistics and Integrative Biology (CNRS USR3756) - Structural Bioinformatics Unit, Institut Pasteur, Paris, France.|Sorbonne Université / UPMC, CNRS, IBPS, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), UMR 7238, Paris, France.|MaIAGE, INRA, UPSay, Jouy-en-Josas, France and LIMSI, CNRS, UPSay, Orsay, France.|Sorbonne Université / UPMC, Ecole Normale Supérieure - PLS Research University, Département de Chimie, CNRS, Laboratoire des Biomolécules, UMR 7203 - Univ. Paris Diderot, Sorbonne Paris Cité, Paris, France.|Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, UPSay, Gif-sur-Yvette cedex, France.|Mitochondria, Metals and Oxidative Stress Group, Institut Jacques Monod, UMR 7592, Univ. Paris Diderot, CNRS, Sorbonne Paris Cité, Paris, France.|Sorbonne Université / UPMC, CNRS, IBPS, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), UMR 7238, Paris, France.|Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, UPSay, Gif-sur-Yvette cedex, France.|Sorbonne Université / UPMC, CNRS, IBPS, Laboratoire de Biologie Computationnelle et Quantitative (LCQB), UMR 7238, Paris, France.|Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Univ. Paris-Sud, UPSay, Gif-sur-Yvette cedex, France.