Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org|Department of Biostatistics, St Jude Childrens Research Hospital, Memphis, TN, USA. stanley.pounds@stjude.org