Department of Medicine, Solna, Karolinska Institutet, and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.|Department of Medicine, Solna, Karolinska Institutet, and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.|Department of Medicine, Solna, Karolinska Institutet, and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.|Department of Medicine, Solna, Karolinska Institutet, and Karolinska University Hospital, SE-171 76 Stockholm, Sweden.