Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. rscharp1@jhmi.edu|Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. rscharp1@jhmi.edu|Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. rscharp1@jhmi.edu|Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. rscharp1@jhmi.edu|Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. rscharp1@jhmi.edu|Department of Oncology, Johns Hopkins University, Baltimore, MD, USA. rscharp1@jhmi.edu