Telethon Institute of Genetics and Medicine, Via P. Castellino 111, 80131 Naples, Interactive SRL, Via Fratelli Bisogno 5, 83100 Avellino, Dip. di Studi Aziendali e Quantitativi Università degli studi di Napoli Parthenope, Via Generale Parisi 13, 80132 Naples, Institute for High-Performance Computing - ICAR - CNR, Via P. Castellino 111, 80131 Naples and Department of Electrical Engineering and Information Technology, University of Naples Federico II, Via Claudio 21, 80125 Naples, ItalyTelethon Institute of Genetics and Medicine, Via P. Castellino 111, 80131 Naples, Interactive SRL, Via Fratelli Bisogno 5, 83100 Avellino, Dip. di Studi Aziendali e Quantitativi Università degli studi di Napoli Parthenope, Via Generale Parisi 13, 80132 Naples, Institute for High-Performance Computing - ICAR - CNR, Via P. Castellino 111, 80131 Naples and Department of Electrical Engineering and Information Technology, University of Naples Federico II, Via Claudio 21, 80125 Naples, Italy.