School of Computer Science and Engineering, Nanyang Technological University, 50 Nanyang Ave, Singapore, 639798, Singapore.|Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Childrens Hospital, 700 Childrens Drive, Columbus, USA.|Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Childrens Hospital, 700 Childrens Drive, Columbus, USA.|School of Computer Science and Engineering, Nanyang Technological University, 50 Nanyang Ave, Singapore, 639798, Singapore. ssundaram@ntu.edu.sg.|Laboratory of Theory of Biopolymers, Faculty of Chemistry, University of Warsaw, Pasteura 1, Warsaw, 02-093, Poland.