Electrical and Computer Engineering Department, Center for Bio-Image Informatics, University of California Santa Barbara, CA 93106, USA. elisa.drelie@ieee.org|Electrical and Computer Engineering Department, Center for Bio-Image Informatics, University of California Santa Barbara, CA 93106, USA. elisa.drelie@ieee.org|Electrical and Computer Engineering Department, Center for Bio-Image Informatics, University of California Santa Barbara, CA 93106, USA. elisa.drelie@ieee.org|Electrical and Computer Engineering Department, Center for Bio-Image Informatics, University of California Santa Barbara, CA 93106, USA. elisa.drelie@ieee.org|Electrical and Computer Engineering Department, Center for Bio-Image Informatics, University of California Santa Barbara, CA 93106, USA. elisa.drelie@ieee.org