Center for Computational Biology and Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.|Center for Computational Biology and Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.|Center for Computational Biology and Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.|Center for Computational Biology and Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.|Center for Computational Biology and Bioinformatics, Department of Medicine, University of California, San Diego, La Jolla, CA, USA.