Center for Bioinformatics, Saarland University, Saarland Informatics Campus E2.1, Saarbrxc3xbccken, 66123, Germany.|Center for Bioinformatics, Saarland University, Saarland Informatics Campus E2.1, Saarbrxc3xbccken, 66123, Germany.|European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.|European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.|Department of Genome Sciences, University of Washington, Seattle, WA, USA.|European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.|Center for Bioinformatics, Saarland University, Saarland Informatics Campus E2.1, Saarbrxc3xbccken, 66123, Germany.