Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. chao.cheng@dartmouth.edu|Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. chao.cheng@dartmouth.edu|Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. chao.cheng@dartmouth.edu|Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA. chao.cheng@dartmouth.edu