Charles Perkins Centre and School of Mathematics and Statistics, University of Sydney, Camperdown, NSW 2006, Australia.|Systems Biology Group, Epigenetics & Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, RTP, NC 27709, USA.|Victor Chang Cardiac Research Institute.|Victor Chang Cardiac Research Institute.|Charles Perkins Centre and School of Mathematics and Statistics, University of Sydney, Camperdown, NSW 2006, Australia.|Victor Chang Cardiac Research Institute.