Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu|Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu|Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu|Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu|Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu|Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu|Department of Pharmacology and Experimental Therapeutics, Thomas Jefferson University, Philadelphia, PA 19107, USA. I_Chervoneva@mail.jci.tju.edu