Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.|Department of Chemistry, The Cooper Union, New York, New York, United States of America.|Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.|Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.