School of Biological Sciences, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK. david.c.hoyle@man.ac.uk|School of Biological Sciences, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK. david.c.hoyle@man.ac.uk|School of Biological Sciences, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK. david.c.hoyle@man.ac.uk|School of Biological Sciences, University of Manchester, Stopford Building, Oxford Rd, Manchester M13 9PT, UK. david.c.hoyle@man.ac.uk