Department of Biostatistics, University of Washington, Seattle, WA, USA.|Department of Medicine, Harvard Medical School, Boston, MA, USA.|Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.|Department of Biostatistics, University of Washington, Seattle, WA, USA.|Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.|Department of Biostatistics, University of Washington, Seattle, WA, USA.|Department of Biostatistics, University of Washington, Seattle, WA, USA.|Department of Biostatistics, University of Washington, Seattle, WA, USA.