Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, Peoples Republic of China.|Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, Peoples Republic of China.|Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, Peoples Republic of China.|Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (and Peking Union Medical College, National Laboratory of Medical Molecular Biology, Beijing, 100005, Peoples Republic of China.