Department of Biostatistics, Division of Information Sciences, City of Hope National Medical Center, Beckman Research Institute, 1500 Duarte Rd, Duarte, CA 91010, USA. fxhong@jimmy.harvard.edu|Department of Biostatistics, Division of Information Sciences, City of Hope National Medical Center, Beckman Research Institute, 1500 Duarte Rd, Duarte, CA 91010, USA. fxhong@jimmy.harvard.edu