Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.|Department of Molecular Biology, Princeton University, Princeton, New Jersey, United States of America.|Department of Biochemistry and Molecular Biology, and the Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania, United States of America.|Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey, United States of America.