Department of Pharmaceutical Sciences, State University of New York Buffalo, NY 14260, USA.|Department of Pharmaceutical Sciences, State University of New York Buffalo, NY 14260, USA.|Department of Pharmaceutical Sciences, State University of New York Buffalo, NY 14260, USA.|Department of Pharmaceutical Sciences, State University of New York Buffalo, NY 14260, USA.|Department of Pharmaceutical Sciences, State University of New York Buffalo, NY 14260, USA.