Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.|Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.