PRESTO, Japan Science and Technology Agency, Saitama 332-0012, Japan.|Center for Genomic Medicine, Graduate School of Medicine, Kyoto University, Kyoto, 606-8507 Japan.|Department of Computational Biology and Medical Science, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8561, Japan.|Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan.