Department of Applied Statistics, Chung-Ang University, Seoul, 156-756, South Korea.|Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Cheongju-si, Chungcheongbuk-do, 363-951, South Korea.|Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, 151-742, South Korea.|Naver Labs, 235 Pangyoyeok-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13494, South Korea.|Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Cheongju-si, Chungcheongbuk-do, 363-951, South Korea.|Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Cheongju-si, Chungcheongbuk-do, 363-951, South Korea.|Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Cheongju-si, Chungcheongbuk-do, 363-951, South Korea.|Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, 44106, USA.|Division of Structural and Functional Genomics, Center for Genome Science, National Institute of Health, Cheongju-si, Chungcheongbuk-do, 363-951, South Korea. kbj6181@cdc.go.kr.|Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, 151-742, South Korea. won1@snu.ac.kr.