The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp|The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, Japan. s-ayumu@ims.u-tokyo.ac.jp