Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA. chashen@iupui.edu|Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA. chashen@iupui.edu|Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA. chashen@iupui.edu|Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA. chashen@iupui.edu|Division of Biostatistics, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA. chashen@iupui.edu