Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA. linwang@hsph.harvard.edu|Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA. linwang@hsph.harvard.edu|Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA. linwang@hsph.harvard.edu|Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA. linwang@hsph.harvard.edu