Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA. chai.high@mayo.edu|Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA. chai.high@mayo.edu|Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA. chai.high@mayo.edu|Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA. chai.high@mayo.edu|Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA. chai.high@mayo.edu|Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA. chai.high@mayo.edu