Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.|Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.|Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.|Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.|Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.|Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.|Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan Computational Biology Research Center (CBRC), National Institute of Advanced Industrial Science and Technology (AIST), Tokyo 135-0064, Japan, Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Hokkaido 062-8517, Japan, Fermlab Inc., Tokyo 135-0021, Japan, INTEC Inc., Tokyo 136-8637, Japan, and Department of Computational Biology, Graduate School of Frontier Sciences, the University of Tokyo, Chiba 277-8561, Japan.