Department of Statistics, University of Georgia, Athens, GA 30602, USA. tn@uga.edu.|Department of Statistics, University of Georgia, Athens, GA 30602, USA. tn@uga.edu.|Research and Development department, Cellectis, 8 rue de la Croix Jarry, Paris 75013, France. philippe.duchateau@cellectis.com.|Research and Development department, Cellectis, 8 rue de la Croix Jarry, Paris 75013, France. philippe.duchateau@cellectis.com.|Research and Development department, Cellectis, 8 rue de la Croix Jarry, Paris 75013, France. philippe.duchateau@cellectis.com.