Dan L. Duncan Cancer Center, Department of Medicine, Section of Hematology and Oncology and Department of Molecular and Cellular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA Dan L. Duncan Cancer Center, Department of Medicine, Section of Hematology and Oncology and Department of Molecular and Cellular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA Dan L. Duncan Cancer Center, Department of Medicine, Section of Hematology and Oncology and Department of Molecular and Cellular Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.