Computational and Systems Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America. betel@cbio.mskcc.org|Computational and Systems Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America. betel@cbio.mskcc.org|Computational and Systems Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America. betel@cbio.mskcc.org|Computational and Systems Biology Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America. betel@cbio.mskcc.org