Department of Biostatistics, Department of Computational Biology and Department of Pathology, St. Jude Childrens Research Hospital, Memphis, TN 38135, USA. stanley.pounds@stjude.org|Department of Biostatistics, Department of Computational Biology and Department of Pathology, St. Jude Childrens Research Hospital, Memphis, TN 38135, USA. stanley.pounds@stjude.org|Department of Biostatistics, Department of Computational Biology and Department of Pathology, St. Jude Childrens Research Hospital, Memphis, TN 38135, USA. stanley.pounds@stjude.org|Department of Biostatistics, Department of Computational Biology and Department of Pathology, St. Jude Childrens Research Hospital, Memphis, TN 38135, USA. stanley.pounds@stjude.org|Department of Biostatistics, Department of Computational Biology and Department of Pathology, St. Jude Childrens Research Hospital, Memphis, TN 38135, USA. stanley.pounds@stjude.org|Department of Biostatistics, Department of Computational Biology and Department of Pathology, St. Jude Childrens Research Hospital, Memphis, TN 38135, USA. stanley.pounds@stjude.org