Heidelberg Institutes for Theoretical Studies gGmbH, Heidelberg, Germany.|Heidelberg Institutes for Theoretical Studies gGmbH, Heidelberg, Germany.|Eidgenössische Technische Hochschule Zürich, Department of Biosystem Science and Engineering, Basel, Switzerland.|Heidelberg Institutes for Theoretical Studies gGmbH, Heidelberg, Germany, CAS-MPG Partner Institute and Key Laboratory for Computational Biology, Shanghai, China.