Department of BioMedical Informatics, Columbia University New York, NY 10032, USA. lifeng.chen@dbmi.columbia.edu|Department of BioMedical Informatics, Columbia University New York, NY 10032, USA. lifeng.chen@dbmi.columbia.edu|Department of BioMedical Informatics, Columbia University New York, NY 10032, USA. lifeng.chen@dbmi.columbia.edu