Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80133 Naples, Italy. dibernardo@tigem.it|Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80133 Naples, Italy. dibernardo@tigem.it|Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80133 Naples, Italy. dibernardo@tigem.it