Department of Biochemistry, LKS Faculty of Medicine, Hong Kong SAR, Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, Guangdong 518057, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory, Department of Computer Science, Department of Pathology and Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Department of Biochemistry, LKS Faculty of Medicine, Hong Kong SAR, Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, Guangdong 518057, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory, Department of Computer Science, Department of Pathology and Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China Department of Biochemistry, LKS Faculty of Medicine, Hong Kong SAR, Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, Guangdong 518057, HKU-BGI Bioinformatics Algorithms and Core Technology Research Laboratory, Department of Computer Science, Department of Pathology and Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.