Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. wuw2@upmc.edu|Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. wuw2@upmc.edu|Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. wuw2@upmc.edu|Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. wuw2@upmc.edu|Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA. wuw2@upmc.edu