Department of Computer Science, University of Kentucky, Lexington, KY, USA.|Department of Computer Science,University of Kentucky, Lexington, KY, USA.|Biostatistics and Bioinformatics Shared Resource Facility, Markey Cancer Center, University of Kentucky, Lexington, KY, USA.|Department of Computer Science, University of Kentucky, Lexington, KY, USA.|Department of Computer Engineering, UC Santa Cruz, Santa Cruz, CA, USA.|Department of Computer Science, University of Kentucky, Lexington, KY, USA.