Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK. euan.adie@ed.ac.uk|Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK. euan.adie@ed.ac.uk|Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK. euan.adie@ed.ac.uk|Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK. euan.adie@ed.ac.uk|Medical Genetics Section, Department of Medical Sciences, The University of Edinburgh, Edinburgh, UK. euan.adie@ed.ac.uk