Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.|Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.|Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.|Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.|Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada Department of Computer Science, The Donnelly Centre, University of Toronto, Toronto, Ontario M5S 3E1, Canada, College of Information Science and Engineering, Hunan University, Changsha, Hunan, 410082, China and Banting and Best Department of Medical Research and Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 3E1, Canada.