Animals|Calcium Signaling|Cell Line|Complement C5a|Computational Biology|Feedback, Physiological|GTP-Binding Protein alpha Subunits, Gi-Go|GTP-Binding Protein alpha Subunits, Gq-G11|Ligands|Macrophages|Mice|Models, Biological|RNA Interference|Receptor Cross-Talk|Receptors, G-Protein-Coupled|Signal Transduction|Uridine Diphosphate