Amino Acid Sequence|Anaphase-Promoting Complex-Cyclosome|Humans|Molecular Dynamics Simulation|Molecular Sequence Annotation|Molecular Sequence Data|Phosphorylation|Principal Component Analysis|Protein Structure, Tertiary|Recombinant Proteins|Saccharomyces cerevisiae Proteins|Thermodynamics|Ubiquitin|Ubiquitin-Conjugating Enzymes|Ubiquitin-Protein Ligase Complexes