Department of Pharmacology and Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA. jgu@sdsc.edu|Department of Pharmacology and Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA. jgu@sdsc.edu|Department of Pharmacology and Biomedical Sciences Graduate Program, University of California San Diego, La Jolla, California, USA. jgu@sdsc.edu