Division of Informatics, Imaging and Data Sciences, The University of Manchester, M13 9PG, UK.|Division of Informatics, Imaging and Data Sciences, The University of Manchester, M13 9PG, UK.|Division of Informatics, Imaging and Data Sciences, The University of Manchester, M13 9PG, UK.|Division of Informatics, Imaging and Data Sciences, The University of Manchester, M13 9PG, UK.|Division of Informatics, Imaging and Data Sciences, The University of Manchester, M13 9PG, UK.