Department of Surgery and Cancer, Section of Computational and Systems Medicine, Imperial College London, Exhibition Road, London SW7 2AZ, UK and Translational Research Unit, Chulabhorn Research Institute, Bangkok 10210, Thailand Department of Surgery and Cancer, Section of Computational and Systems Medicine, Imperial College London, Exhibition Road, London SW7 2AZ, UK and Translational Research Unit, Chulabhorn Research Institute, Bangkok 10210, Thailand.