Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, Universtiy of Louisville, Louisville, KY 40292, USA. guy.brock@louisville.edu|Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, Universtiy of Louisville, Louisville, KY 40292, USA. guy.brock@louisville.edu|Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, Universtiy of Louisville, Louisville, KY 40292, USA. guy.brock@louisville.edu|Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, Universtiy of Louisville, Louisville, KY 40292, USA. guy.brock@louisville.edu|Department of Bioinformatics and Biostatistics, School of Public Health and Information Sciences, Universtiy of Louisville, Louisville, KY 40292, USA. guy.brock@louisville.edu