UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA 95064, USA.|Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, UK.|UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA 95064, USA.|UC Santa Cruz Genomics Institute, University of California, Santa Cruz, CA 95064, USA.|Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton CB10 1SA, UK.