Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA. zhou@gnf.org|Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA. zhou@gnf.org|Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA. zhou@gnf.org|Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA. zhou@gnf.org|Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA. zhou@gnf.org|Genomics Institute of the Novartis Research Foundation San Diego, CA 92121, USA. zhou@gnf.org