Imaging and Bio-informatics group, LIACS, Leiden University, Niels Bohrweg 1, Leiden, 2333, CA, The Netherlands.|Division of Toxicology, LACDR, Leiden University, Einsteinweg 55, Leiden, 2333, CC, The Netherlands.|Imaging and Bio-informatics group, LIACS, Leiden University, Niels Bohrweg 1, Leiden, 2333, CA, The Netherlands.|Biomechanics Laboratory, Erasmus MC, Wytemaweg 80, Rotterdam, 3015, CN, The Netherlands.|Imaging and Bio-informatics group, LIACS, Leiden University, Niels Bohrweg 1, Leiden, 2333, CA, The Netherlands. f.j.verbeek@liacs.leidenuniv.nl.