Department of Microbiology, Immunology and Tropical Medicine, Research Center for Neglected Diseases of Poverty, School of Medicine and Health Sciences, George Washington University, Washington, DC, 20052, USA, QIMR Berghofer Medical Research Institute, Infectious Disease and Cancer and The University of Queensland, School of Biomedical Sciences, Brisbane, Queensland, 4072, Australia Department of Microbiology, Immunology and Tropical Medicine, Research Center for Neglected Diseases of Poverty, School of Medicine and Health Sciences, George Washington University, Washington, DC, 20052, USA, QIMR Berghofer Medical Research Institute, Infectious Disease and Cancer and The University of Queensland, School of Biomedical Sciences, Brisbane, Queensland, 4072, Australia.