Dept. of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.|Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.|Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.|Dept. of Bioinformatics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.