The Microsoft Research-University of Trento Centre for Computational Systems Biology, Rovereto, Italy.|The Microsoft Research-University of Trento Centre for Computational Systems Biology, Rovereto, Italy, Department of Mathematics, University of Trento, Povo (TN), Italy.|Department of Computational Biology, Research and Innovation Centre, Fondazione Edmund Mach, San Michele allAdige, Italy, Randall Division of Cell and Molecular Biophysics and Institute for Mathematical and Molecular Biomedicine, Kings College London, London, United Kingdom.