Department of Gynecologic Oncology, The Affiliated Womens Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310006, Institute of Bioinformatics, Zhejiang University, Hangzhou, Zhejiang 310058, China, Division of Respiratory Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang 310058, China, Department of Physiology and the Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA and Human Molecular and Genetics Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.