Computer Laboratory, University of Cambridge, Cambridge CB3 0FD, UK and Institute of Environmental Medicine, Karolinska Institutet, Stockholm SE-171 77, Sweden.|Computer Laboratory, University of Cambridge, Cambridge CB3 0FD, UK and Institute of Environmental Medicine, Karolinska Institutet, Stockholm SE-171 77, Sweden.|Computer Laboratory, University of Cambridge, Cambridge CB3 0FD, UK and Institute of Environmental Medicine, Karolinska Institutet, Stockholm SE-171 77, Sweden.|Computer Laboratory, University of Cambridge, Cambridge CB3 0FD, UK and Institute of Environmental Medicine, Karolinska Institutet, Stockholm SE-171 77, Sweden.