Antineoplastic Agents, Phytogenic|Caco-2 Cells|Camptothecin|Circadian Rhythm|Circadian Rhythm Signaling Peptides and Proteins|Computational Biology|DNA Topoisomerases, Type I|Drug Administration Schedule|Drug Chronotherapy|Gene Expression Profiling|Gene Expression Regulation, Neoplastic|Humans|Irinotecan|Models, Biological|RNA, Messenger