South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa. ruben@sanbi.ac.za.|South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa. ekow@sanbi.ac.za.|South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa. eddkimm@gmail.com.|Department of Biotechnology, University of the Western Cape, Bellville, South Africa. wolf-dieter.schubert@up.ac.za.|South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa. alan@sanbi.ac.za.