Department of Electrical and Computational Engineering, Iowa State University, Howe Hall, Ames, 50011-3060, USA. ruolin@iastate.edu.|Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, North Carolina Research Campus, 600 Laureate Way, Kannapolis, 28081, NC, USA. Ann.Loraine@uncc.edu.|Department of Electrical and Computational Engineering, Iowa State University, Howe Hall, Ames, 50011-3060, USA. julied@iastate.edu.