Department of Bioinformatics, Tongji University, 200092, Shanghai, China. qiliu@tongji.edu.cn|Department of Bioinformatics, Tongji University, 200092, Shanghai, China. qiliu@tongji.edu.cn|Department of Bioinformatics, Tongji University, 200092, Shanghai, China. qiliu@tongji.edu.cn|Department of Bioinformatics, Tongji University, 200092, Shanghai, China. qiliu@tongji.edu.cn