Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK. g.izuogu@ncl.ac.uk.|Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK.|Security Forces Hostpital, P. O. Box 2748-24268-8541, Makkah, Kingdom of Saudi Arabia.|Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK.|Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK.|Institute of Genetic Medicine, Newcastle University, Newcastle Upon Tyne, UK.