Department of Biomedical Informatics (DBMI) Department of Systems Biology Center for Computational Biology and Bioinformatics (C2B2), Columbia University, New York, NY, USA.|Department of Systems Biology Center for Computational Biology and Bioinformatics (C2B2), Columbia University, New York, NY, USA Scuola Superiore SantAnna, Pisa, Italy.|Department of Systems Biology.|Department of Biomedical Informatics (DBMI) Department of Systems Biology Center for Computational Biology and Bioinformatics (C2B2), Columbia University, New York, NY, USA Department of Biochemistry and Molecular Biophysics Institute for Cancer Genetics Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY, USA.