Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada. m.robinson@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada. m.robinson@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada. m.robinson@utoronto.ca|Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada. m.robinson@utoronto.ca