Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan.|Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan.|Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan.|Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan.|Institute of Biomedical Informatics, Center for Systems and Synthetic Biology, National Yang-Ming University, Taipei 112, Department of Life Science, Graduate Institute of Biomedical Electronics and Bioinformatics and Institute of Molecular and Cellular Biology, National Taiwan University, Taipei 106, Taiwan.