Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.|Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.|Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Childrens Hospital, Boston, MA 02115, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA 2142, USA, Department of Systems Biology, Center for Biological Sequence Analysis, Technical University of Denmark, 2800 Lyngby, Denmark and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.