Department of Computer and Information Sciences, University of Delaware, Newark, Delaware, United States of America.|Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, United States of America, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, Delaware, United States of America.|Center for Bioinformatics and Computational Biology, University of Delaware, Newark, Delaware, United States of America.|Department of Computer and Information Sciences, University of Delaware, Newark, Delaware, United States of America.|Department of Computer and Information Sciences, University of Delaware, Newark, Delaware, United States of America, Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, United States of America, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, Delaware, United States of America.|Department of Computer and Information Sciences, University of Delaware, Newark, Delaware, United States of America.