Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory Richland, WA, USA. ronald.taylor@pnl.gov|Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory Richland, WA, USA. ronald.taylor@pnl.gov|Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory Richland, WA, USA. ronald.taylor@pnl.gov|Computational Biology and Bioinformatics Group, Pacific Northwest National Laboratory Richland, WA, USA. ronald.taylor@pnl.gov