Computational gene prioritization methods are useful to help identify susceptibility genes potentially being involved in genetic disease. Recently, text mining techniques have been applied to extract prior knowledge from text-based genomic information sources and this knowledge can be used to improve the prioritization process. However, the effect of various vocabularies, representations and ranking algorithms on text mining for gene prioritization is still an issue that requires systematic and comparative studies. Therefore, a benchmark study about the vocabularies, representations and ranking algorithms in gene prioritization by text mining is discussed in this article.