Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu|Department of Biostatistics, Virginia Commonwealth University, 730 East Broad St,, Richmond, VA, USA. kjarcher@vcu.edu