School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28759 Bremen, Germany. w.henkel@jacobs-university.de.|School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D-28759 Bremen, Germany. w.henkel@jacobs-university.de.|Department of Biology, The Bioinformatics Centre, University of Copenhagen, Ole Maaloes Vej 5, Copenhagen, DK2200, Denmark. albin@binf.ku.dk.|Department of Biology, The Bioinformatics Centre, University of Copenhagen, Ole Maaloes Vej 5, Copenhagen, DK2200, Denmark. albin@binf.ku.dk.