Cardiovascular Division, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.|Cardiovascular Division, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.|Channing Division of Network Medicine, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.|Cardiovascular Division, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.