Theoretical Biology and Bioinformatics, Utrecht University, Utrecht, The Netherlands. ilka.hoof@gmail.com|Theoretical Biology and Bioinformatics, Utrecht University, Utrecht, The Netherlands. ilka.hoof@gmail.com|Theoretical Biology and Bioinformatics, Utrecht University, Utrecht, The Netherlands. ilka.hoof@gmail.com|Theoretical Biology and Bioinformatics, Utrecht University, Utrecht, The Netherlands. ilka.hoof@gmail.com