Department of Biomedical Statistics and Informatics, Mayo Clinic, 200 1st street SW, Rochester, MN 55905, USA.|Department of Biomedical Statistics and Informatics, Mayo Clinic, 200 1st street SW, Rochester, MN 55905, USA.|Department of Biomedical Statistics and Informatics, Mayo Clinic, 200 1st street SW, Rochester, MN 55905, USA.|Department of Biomedical Statistics and Informatics, Mayo Clinic, 200 1st street SW, Rochester, MN 55905, USA.|Department of Biomedical Statistics and Informatics, Mayo Clinic, 200 1st street SW, Rochester, MN 55905, USA.