Department of Biostatistics, MS 262 St Jude Childrens Research Hospital, 332 N. Lauderdale Street, Memphis, TN 38105-2794, USA. stanley.pounds@stjude.org|Department of Biostatistics, MS 262 St Jude Childrens Research Hospital, 332 N. Lauderdale Street, Memphis, TN 38105-2794, USA. stanley.pounds@stjude.org