Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Ave, Boston, MA, 02115, USA.|Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Ave, Boston, MA, 02115, USA.|Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Ave, Boston, MA, 02115, USA.|Laboratory of Systems Pharmacology, Harvard Medical School, 200 Longwood Ave, Boston, MA, 02115, USA.