Department of Biometry, Hannover Medical School, Carl-Neuberg-Str, 1, D-30625 Hannover, Germany. froemke.cornelia@mh-hannover.de|Department of Biometry, Hannover Medical School, Carl-Neuberg-Str, 1, D-30625 Hannover, Germany. froemke.cornelia@mh-hannover.de|Department of Biometry, Hannover Medical School, Carl-Neuberg-Str, 1, D-30625 Hannover, Germany. froemke.cornelia@mh-hannover.de