Department of Statistics, University of Warwick, Coventry CV4 7AL, UK.|Department of Organismic and Evolutionary Biology, Harvard University, MA 02138, US, Department of Ecology and Evolutionary Biology, Brown University, RI 02912, US, Center for Computational Molecular Biology, Brown University.|Department of Statistics, University of Washington, WA 98195, US.|Department of Statistics, University of Washington, WA 98195, US, Department of Biology, University of Washington and.|Department of Statistics, University of California, Irvine, CA 92697, US.