Dept. of Informatics, Systems and Communication, University of Milan-Bicocca, 20126, Milan, Italy.|Dept. of Biotechnology and Biosciences, University of Milan-Bicocca, 20126, Milan, Italy.|SYSBIO Centre of Systems Biology, 20126, Milan, Italy.|Dept. of Informatics, Systems and Communication, University of Milan-Bicocca, 20126, Milan, Italy.|SYSBIO Centre of Systems Biology, 20126, Milan, Italy.|Dept. of Informatics, Systems and Communication, University of Milan-Bicocca, 20126, Milan, Italy.|Dept. of Molecular Cell Physiology, Faculty of Earth and Life Sciences, VU University, Amsterdam, The Netherlands.|SYSBIO Centre of Systems Biology, 20126, Milan, Italy.|SYSBIO Centre of Systems Biology, 20126, Milan, Italy.|Dept. of Informatics, Systems and Communication, University of Milan-Bicocca, 20126, Milan, Italy.