Biotechnology Center of the TU Dresden, Tatzberg 47-51, Dresden, 01307, Germany. paul.mueller@biotec.tu-dresden.de.|Biotechnology Center of the TU Dresden, Tatzberg 47-51, Dresden, 01307, Germany. mirjam.schuermann@biotec.tu-dresden.de.|Biotechnology Center of the TU Dresden, Tatzberg 47-51, Dresden, 01307, Germany. jochen.guck@biotec.tu-dresden.de.