CFisUC, Department of Physics, University of Coimbra, Coimbra, Portugal.|Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.|Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.|Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.|Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal, Department of Complementary Sciences, Coimbra Health School (ESTeSC), Instituto Politécnico de Coimbra, Coimbra, Portugal.|Centre for Genomics and Oncological Research: Pfizer/Universidad de Granada/Junta de Andalucía (GENYO), Granada, Spain.|Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.|Institute for Biomedical Imaging and Life Sciences (IBILI), Faculty of Medicine, University of Coimbra, Coimbra, Portugal.|CFisUC, Department of Physics, University of Coimbra, Coimbra, Portugal.