Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, Peoples Republic of China.|State Key Laboratory of Software Engineering (Wuhan University) and Wuhan University School of Computer Sciences, Wuhan 430072, Peoples Republic of China and.|State Key Laboratory of Software Engineering (Wuhan University) and Wuhan University School of Computer Sciences, Wuhan 430072, Peoples Republic of China and.|Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, Peoples Republic of China, Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, Peoples Republic of China.