School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China|Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong, China.|School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China|School of Biomedical Engineering, Science and Health System, Drexel University, Philadelphia, PA, USA.|Institute for Human Genetics.|Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong, China.|School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, China