Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, Massachusetts, USA.