Institute for Systems Biology, 1441 N. 34th St. Seattle, WA 98103-8904, USA. dreiss@systemsbiology.org|Institute for Systems Biology, 1441 N. 34th St. Seattle, WA 98103-8904, USA. dreiss@systemsbiology.org|Institute for Systems Biology, 1441 N. 34th St. Seattle, WA 98103-8904, USA. dreiss@systemsbiology.org