Joint Center for Molecular Modeling, Burnham Institute for Medical Research, La Jolla, CA 92037, USA. mallikav@burnham.org|Joint Center for Molecular Modeling, Burnham Institute for Medical Research, La Jolla, CA 92037, USA. mallikav@burnham.org|Joint Center for Molecular Modeling, Burnham Institute for Medical Research, La Jolla, CA 92037, USA. mallikav@burnham.org