Institute of Genomics and Systems Biology, Committee on Development, Regeneration, and Stem Cell Biology and Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.|Institute of Genomics and Systems Biology, Committee on Development, Regeneration, and Stem Cell Biology and Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.|Institute of Genomics and Systems Biology, Committee on Development, Regeneration, and Stem Cell Biology and Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.