Department of Computational Biology and Medical Science, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8561, Japan.|Foundation for Biomedical Research and Innovation, Hyogo 650-0047, Japan.|RIKEN Advanced Institute for Computational Science, Hyogo 650-0047, Japan.|RIKEN Advanced Institute for Computational Science, Hyogo 650-0047, Japan.|Department of Computational Biology and Medical Science, Graduate School of Frontier Sciences, The University of Tokyo, Chiba 277-8561, Japan.