Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taiwan. pchsu@ym.edu.tw