Biotechnology Program, CIS, University of Pennsylvania, 3330 Walnut Street, Philadelphia, PA 19104, USA. myar@seas.upenn.edu|Biotechnology Program, CIS, University of Pennsylvania, 3330 Walnut Street, Philadelphia, PA 19104, USA. myar@seas.upenn.edu|Biotechnology Program, CIS, University of Pennsylvania, 3330 Walnut Street, Philadelphia, PA 19104, USA. myar@seas.upenn.edu