NIH/National Center for Advancing Translational Sciences, Rockville, MD, USA.|Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, Jefferson, AR, USA.|NIH/National Center for Advancing Translational Sciences, Rockville, MD, USA.|Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, Jefferson, AR, USA. weida.tong@fda.hhs.gov.