Samuel Lunenfeld Research Institute, Mt, Sinai Hospital, Toronto ON Canada M5G 1X5, Dept, of Biochemistry, University of Toronto, Toronto ON Canada M5S 1A8. gary.bader@utoronto.ca|Samuel Lunenfeld Research Institute, Mt, Sinai Hospital, Toronto ON Canada M5G 1X5, Dept, of Biochemistry, University of Toronto, Toronto ON Canada M5S 1A8. gary.bader@utoronto.ca