Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com|Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com