Broad Institute of MIT and Harvard, MA 02142 and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA Broad Institute of MIT and Harvard, MA 02142 and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.|Broad Institute of MIT and Harvard, MA 02142 and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA Broad Institute of MIT and Harvard, MA 02142 and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.|Broad Institute of MIT and Harvard, MA 02142 and Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.