Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Gualtar Campus, Braga, Portugal. mmcosta@ecsaude.uminho.pt|Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Gualtar Campus, Braga, Portugal. mmcosta@ecsaude.uminho.pt|Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Gualtar Campus, Braga, Portugal. mmcosta@ecsaude.uminho.pt|Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Gualtar Campus, Braga, Portugal. mmcosta@ecsaude.uminho.pt