Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.|Center for Biostatistics, The Ohio State University Wexner Medical Center.|Department of Electrical and Computer Engineering.|Department of Pathology.|Guangdong Provincial Key Laboratory of Medical Image Processing, School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.|Department of Electrical and Computer Engineering.