Institute of Biotechnology, Research Centre Jülich, 52425 Jülich, Germany. michael.weitzel@uni-siegen.de|Institute of Biotechnology, Research Centre Jülich, 52425 Jülich, Germany. michael.weitzel@uni-siegen.de|Institute of Biotechnology, Research Centre Jülich, 52425 Jülich, Germany. michael.weitzel@uni-siegen.de