Department of Mathematics and Statistics, University of Reading, Reading, Berkshire, United Kingdom.|Institute for Cardiovascular and Metabolic Research and School of Biological Sciences, University of Reading, Reading, Berkshire, United Kingdom.|Institute for Cardiovascular and Metabolic Research and School of Biological Sciences, University of Reading, Reading, Berkshire, United Kingdom.|Institute for Cardiovascular and Metabolic Research and School of Biological Sciences, University of Reading, Reading, Berkshire, United Kingdom.|Department of Mathematics and Statistics, University of Reading, Reading, Berkshire, United Kingdom.