Institute of Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR), Milan, Italy.|Interuniversity Institute of Bioinformatics in Brussels (IB), Brussels, Belgium.|Institute of Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR), Milan, Italy.|Interuniversity Institute of Bioinformatics in Brussels (IB), Brussels, Belgium.|Department of Informatics, Systems and Communications, University of Milan-Bicocca, Milan, Italy.|Institute of Molecular Bioimaging and Physiology (IBFM), National Research Council (CNR), Milan, Italy. isabella.castiglioni@ibfm.cnr.it.