Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.|Division of Computational Biomedicine, Boston University School of Medicine, Boston, MA, USA. wej@bu.edu.