Adaptor Proteins, Signal Transducing|Cell Line, Tumor|Cell Movement|Computational Biology|Computer Simulation|ErbB Receptors|Feedback, Physiological|Humans|Imaging, Three-Dimensional|MAP Kinase Signaling System|Models, Biological|Neoplasm Invasiveness|Pseudopodia|Tumor Microenvironment|rac1 GTP-Binding Protein|rhoA GTP-Binding Protein