School of Biochemistry and Cell Biology, University College Cork, Western Road, Cork, Ireland. paul.korir@gmail.com.|Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL-60637, USA. paul.geeleher@gmail.com.|School of Mathematics, Statistics and Applied Mathematics, University Road, Galway, Ireland. cathal.seoighe@nuigalway.ie.