Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. r.x.menezes@lumc.nl|Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. r.x.menezes@lumc.nl|Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. r.x.menezes@lumc.nl|Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. r.x.menezes@lumc.nl|Center for Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands. r.x.menezes@lumc.nl