Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. wang.liguo@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. nie.jinfujeff@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. Sicotte.Hugues@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. Li.Ying@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. eckelpassow.jeanette@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. Dasari.Surendra@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. Vedell.Peter@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. Barman.Poulami@mayo.edu.|Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA. Wang.Liewei@mayo.edu.|Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA. Weinshilboum.Richard@mayo.edu.|Department of laboratory medicine and pathology, Mayo Clinic, Rochester, MN, 55905, USA. Jen.Jin@mayo.edu.|Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, 55905, USA. Huang.Haojie@mayo.edu.|Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. kohli.manish@mayo.edu.|Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, 55905, USA. kocher.jeanpierre@mayo.edu.