Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.|Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.|Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.|Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.|Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.|Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.|Center for Statistical Genetics, The Pennsylvania State University, Hershey, PA 17033, USA. rwu@phs.psu.edu.