Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|Machine Learning Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.|Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|School of Medicine, Tsinghua University, Beijing, China.|Department of Internal Medicine I, Universitätsklinikum Frankfurt, Frankfurt, Germany.|Department of Internal Medicine I, Universitätsklinikum Frankfurt, Frankfurt, Germany.|Department of Internal Medicine I, Universitätsklinikum Frankfurt, Frankfurt, Germany.|Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.|Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America.|Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|Machine Learning Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.