Department of Medical, Surgical, Neurological, Metabolic and Ageing Sciences, Second University of Napoli, Napoli, Italy. michele.fratello@unina2.it.|Department of Computer Science, Fisciano, Italy. aserra@unisa.it.|Unit of Systems Toxicology and Nanosafety Research Centre, Finnish Institute of Occupational Health, FIOH, Helsinki, Finland. vittorio.fortino@ttl.fi.|Department of Computer Science, Fisciano, Italy. gianni@unisa.it.|Department of Computer Science, Fisciano, Italy. rtagliaferr@unisa.it.|Unit of Systems Toxicology and Nanosafety Research Centre, Finnish Institute of Occupational Health, FIOH, Helsinki, Finland. dario.greco@ttl.fi.