Department of Biotechnology, College of Life Sciences, Zhejiang University, Hangzhou, 310027, China. alickgf@hotmail.com|Department of Biotechnology, College of Life Sciences, Zhejiang University, Hangzhou, 310027, China. alickgf@hotmail.com|Department of Biotechnology, College of Life Sciences, Zhejiang University, Hangzhou, 310027, China. alickgf@hotmail.com