Institute of Statistical Science, Academia Sinica, Taipei 115, Taiwan and Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan.|Institute of Statistical Science, Academia Sinica, Taipei 115, Taiwan and Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan.|Institute of Statistical Science, Academia Sinica, Taipei 115, Taiwan and Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan.|Institute of Statistical Science, Academia Sinica, Taipei 115, Taiwan and Institute of Biomedical Engineering, National Taiwan University, Taipei 106, Taiwan.