Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.|Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.