Biostatistics and Bioinformatics Unit, Comprehensive Cancer Center, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. deli.wang@ccc.uab.edu|Biostatistics and Bioinformatics Unit, Comprehensive Cancer Center, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. deli.wang@ccc.uab.edu|Biostatistics and Bioinformatics Unit, Comprehensive Cancer Center, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. deli.wang@ccc.uab.edu|Biostatistics and Bioinformatics Unit, Comprehensive Cancer Center, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. deli.wang@ccc.uab.edu|Biostatistics and Bioinformatics Unit, Comprehensive Cancer Center, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. deli.wang@ccc.uab.edu