Humboldt-Universitxc3xa4t zu Berlin, Institute for Computer Science, Knowledge Management in Bioinformatics, 10099 Berlin, Germany, Institute of Pathology, Charitxc3xa9-Universitxc3xa4tsmedizin Berlin, Deutsches Rheuma Forschungszentrum, Charitxc3xa9platz 1, 10117 Berlin, Germany, Department of Telecommunications and Media Informatics, Budapest University of Technology and Economics, 1117 Budapest, Hungary and Integrative Research Institute for the Life Sciences, Humboldt Universitxc3xa4t zu Berlin, Philippstr. 13 Haus 18, 10115 Berlin, Germany Humboldt-Universitxc3xa4t zu Berlin, Institute for Computer Science, Knowledge Management in Bioinformatics, 10099 Berlin, Germany, Institute of Pathology, Charitxc3xa9-Universitxc3xa4tsmedizin Berlin, Deutsches Rheuma Forschungszentrum, Charitxc3xa9platz 1, 10117 Berlin, Germany, Department of Telecommunications and Media Informatics, Budapest University of Technology and Economics, 1117 Budapest, Hungary and Integrative Research Institute for the Life Sciences, Humboldt Universitxc3xa4t zu Berlin, Philippstr. 13 Haus 18, 10115 Berlin, Germany.