The University of Texas MD Anderson Cancer Center, Department of Systems Biology, Houston, Texas, United States of America.|Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, United States of America.|Center for Computational Biology, University of Kansas, Lawrence, Kansas, United States of America.|Center for Computational Biology, University of Kansas, Lawrence, Kansas, United States of America.|Department of Biology and Biochemistry, University of Houston, Houston, Texas, United States of America.|The University of Texas MD Anderson Cancer Center, Department of Systems Biology, Houston, Texas, United States of America.