CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, University of Chinese Academy of Science, Chinese Academy of Sciences, Shanghai 200031, China.|Cambridge Epigenetix, Jonas Webb Building, Babraham Campus, Cambridge CB22xe2x80x893AT, UK.|Medical Genomics Group, Paul OGorman Building, UCL Cancer Institute, University College London, London WC1E 6BT, UK.|CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, University of Chinese Academy of Science, Chinese Academy of Sciences, Shanghai 200031, China.|Medical Genomics Group, Paul OGorman Building, UCL Cancer Institute, University College London, London WC1E 6BT, UK.|Medical Genomics Group, Paul OGorman Building, UCL Cancer Institute, University College London, London WC1E 6BT, UK.|CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, University of Chinese Academy of Science, Chinese Academy of Sciences, Shanghai 200031, China.