Computational and System Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.|Computational and System Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.|Computational and System Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.|Computational and System Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.|Computational and System Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.