Department of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.|Department of Biochemistry and Biophysics, Science for Life Laboratory, Swedish E-Science Research Center, Stockholm University, Solna, Sweden.|Department of Biochemistry and Biophysics, Science for Life Laboratory, Swedish E-Science Research Center, Stockholm University, Solna, Sweden.|Department of Computer Science and Biomedical Informatics, University of Thessaly, Lamia, Greece.