Metabolic Engineering Laboratory, Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, Peoples Republic of China. Wangqingzhao@eyou.com|Metabolic Engineering Laboratory, Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, Peoples Republic of China. Wangqingzhao@eyou.com|Metabolic Engineering Laboratory, Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, Peoples Republic of China. Wangqingzhao@eyou.com|Metabolic Engineering Laboratory, Department of Biochemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin, Peoples Republic of China. Wangqingzhao@eyou.com