Fraunhofer Institute Algorithms and Scientific Computing (SCAI), Department of Bioinformatics, Schloss Birlinghoven, 53574 Sankt Augustin, Germany. roman.klinger@scai.fraunhofer.de|Fraunhofer Institute Algorithms and Scientific Computing (SCAI), Department of Bioinformatics, Schloss Birlinghoven, 53574 Sankt Augustin, Germany. roman.klinger@scai.fraunhofer.de|Fraunhofer Institute Algorithms and Scientific Computing (SCAI), Department of Bioinformatics, Schloss Birlinghoven, 53574 Sankt Augustin, Germany. roman.klinger@scai.fraunhofer.de|Fraunhofer Institute Algorithms and Scientific Computing (SCAI), Department of Bioinformatics, Schloss Birlinghoven, 53574 Sankt Augustin, Germany. roman.klinger@scai.fraunhofer.de|Fraunhofer Institute Algorithms and Scientific Computing (SCAI), Department of Bioinformatics, Schloss Birlinghoven, 53574 Sankt Augustin, Germany. roman.klinger@scai.fraunhofer.de