Bio Systems Analysis Group, Jena Centre for Bioinformatics (JCB) and Department of Mathematics and Computer Science, Friedrich-Schiller-University Jena, D-07743 Jena, Germany.|Bio Systems Analysis Group, Jena Centre for Bioinformatics (JCB) and Department of Mathematics and Computer Science, Friedrich-Schiller-University Jena, D-07743 Jena, Germany.|Bio Systems Analysis Group, Jena Centre for Bioinformatics (JCB) and Department of Mathematics and Computer Science, Friedrich-Schiller-University Jena, D-07743 Jena, Germany.|Bio Systems Analysis Group, Jena Centre for Bioinformatics (JCB) and Department of Mathematics and Computer Science, Friedrich-Schiller-University Jena, D-07743 Jena, Germany.