Gene Center, LMU Munich, Feodor-Lynen-Strasse 25, 81377, Munich and Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany Gene Center, LMU Munich, Feodor-Lynen-Strasse 25, 81377, Munich and Max Planck Institute for Biophysical Chemistry, Am Fassberg 11, 37077 Göttingen, Germany.