Department of Epidemiology and Public Health, Imperial College, London, W2 1PG, UK. lshu-yi.su@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, London, W2 1PG, UK. lshu-yi.su@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, London, W2 1PG, UK. lshu-yi.su@imperial.ac.uk|Department of Epidemiology and Public Health, Imperial College, London, W2 1PG, UK. lshu-yi.su@imperial.ac.uk