School of Biomedical Informatics, The University of Texas Health science center at Houston, Houston, Texas, United States of America.|School of Biomedical Informatics, The University of Texas Health science center at Houston, Houston, Texas, United States of America.|Department of Cancer Biology, Wake Forest Baptist Medical Center, Wake Forest University, Winston Salem, North Carolina, United States of America.|School of Biomedical Informatics, The University of Texas Health science center at Houston, Houston, Texas, United States of America.