National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), Bethesda, MD 20894, USA.|National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), Bethesda, MD 20894, USA.|National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), Bethesda, MD 20894, USA.