Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, China.|Department of Veterinary Surgery & Radiology, College of Veterinary & Animal Sciences, GBPUAT, Pantnagar - 263 145, Uttarakhand, India.|Center for Systems and Computational Biology, Molecular and Cellular Oncogenesis Program, The Wistar Institute, 19104 Philadelphia, PA, USA.|Center for Systems and Computational Biology, Molecular and Cellular Oncogenesis Program, The Wistar Institute, 19104 Philadelphia, PA, USA.