Department of Physics and Astronomy, Rutgers University, Piscataway, New Jersey, United States of America, Center for Biophysics and Computational Biology, Temple University, Philadelphia, Pennsylvania, United States of America.|Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America.|Department of Statistics, Rutgers University, Piscataway, New Jersey, United States of America.|Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America.|Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America.|Infectious Disease Service, San Antonio Military Medical Center, San Antonio, Texas, United States of America.|Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, California, United States of America.|Center for Biophysics and Computational Biology, Temple University, Philadelphia, Pennsylvania, United States of America, Department of Chemistry, and Institute for Computational Molecular Science, Temple University, Philadelphia, Pennsylvania, United States of America.