Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan. yshira@hgc.jp|Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan. yshira@hgc.jp|Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo 108-8639, Japan. yshira@hgc.jp