Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.|Division of Genetics, Department of Medicine, Brigham and Womens Hospital and Harvard Medical School, Boston, MA, USA.