Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Childrens Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.|Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Childrens Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.|Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, BC Childrens Hospital Research Institute, University of British Columbia, Vancouver, BC, Canada.