Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute & Harvard School of Public Health, Boston 02115 MA, USA. parantu.shah@gmail.com|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute & Harvard School of Public Health, Boston 02115 MA, USA. parantu.shah@gmail.com|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute & Harvard School of Public Health, Boston 02115 MA, USA. parantu.shah@gmail.com|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute & Harvard School of Public Health, Boston 02115 MA, USA. parantu.shah@gmail.com|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute & Harvard School of Public Health, Boston 02115 MA, USA. parantu.shah@gmail.com|Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute & Harvard School of Public Health, Boston 02115 MA, USA. parantu.shah@gmail.com