Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast (QUB), Belfast, Northern Ireland, UK. s.zhang@qub.ac.uk.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast (QUB), Belfast, Northern Ireland, UK. s.zhang@qub.ac.uk.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast (QUB), Belfast, Northern Ireland, UK. s.zhang@qub.ac.uk.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast (QUB), Belfast, Northern Ireland, UK. s.zhang@qub.ac.uk.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast (QUB), Belfast, Northern Ireland, UK. s.zhang@qub.ac.uk.|Centre for Cancer Research and Cell Biology (CCRCB), Queens University Belfast (QUB), Belfast, Northern Ireland, UK. s.zhang@qub.ac.uk.