Centre for Integrated Systems Biology and Bioinformatics, Imperial College London, Sir Ernst Chain Building, South Kensington Campus, London SW7 2AZ, UK. chris.tomlinson@imperial.ac.uk|Centre for Integrated Systems Biology and Bioinformatics, Imperial College London, Sir Ernst Chain Building, South Kensington Campus, London SW7 2AZ, UK. chris.tomlinson@imperial.ac.uk|Centre for Integrated Systems Biology and Bioinformatics, Imperial College London, Sir Ernst Chain Building, South Kensington Campus, London SW7 2AZ, UK. chris.tomlinson@imperial.ac.uk|Centre for Integrated Systems Biology and Bioinformatics, Imperial College London, Sir Ernst Chain Building, South Kensington Campus, London SW7 2AZ, UK. chris.tomlinson@imperial.ac.uk