Yale Center for Analytical Sciences, Yale University, New Haven, CT, USA. michael.kane@yale.edu.|Yale Center for Analytical Sciences, Yale University, New Haven, CT, USA. michael.kane@yale.edu.|Yale Center for Analytical Sciences, Yale University, New Haven, CT, USA. michael.kane@yale.edu.|Yale Center for Analytical Sciences, Yale University, New Haven, CT, USA. michael.kane@yale.edu.