Department of Biomedical Informatics, Arizona State University, Scottsdale, AZ, USA.|Department of Biostatistics, Epidemiology, and Informatics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.|Department of Biostatistics, Epidemiology, and Informatics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.|Department of Biomedical Informatics, Arizona State University, Scottsdale, AZ, USA.|Department of Biostatistics, Epidemiology, and Informatics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.