Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02115 and Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.|Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02115 and Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.|Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02115 and Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.|Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02115 and Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.|Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02115 and Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.|Program in Computational Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, Bioinformatics and Computational Biology, Genentech, South San Francisco, CA 94080, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02115 and Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.