Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville TN, USA 37232.|Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville TN, USA, 37232.|Department of Biostatistics, Vanderbilt University Medical Center, Nashville TN, USA 37232.|Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville TN, USA 37232.