Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, Merck Research Laboratories, West Point, PA, USA. barbara_eckman@sbphrd.com