Functional Genomics Center Zurich, University of Zurich/ETH, Zurich, Switzerland. Hubert.Rehrauer@fgcz.uzh.ch.|Functional Genomics Center Zurich, University of Zurich/ETH, Zurich, Switzerland. Hubert.Rehrauer@fgcz.uzh.ch.|Division of Bioinformatics and Biostatistics, National Center for Toxicological Research, Food and Drug Administration Jefferson, Little Rock, Arkansas, USA. jamesj.chen@fda.hhs.gov.