School of Computing, Ulster University, Newtownabbey, UK.|MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.|School of Computing, Ulster University, Newtownabbey, UK.|Almac Diagnostics, Craigavon, UK.|School of Computing, Ulster University, Newtownabbey, UK.|Centre for Cancer Research & Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Queens University, Belfast, UK.|Centre for Cancer Research & Cell Biology, School of Medicine, Dentistry and Biomedical Sciences, Queens University, Belfast, UK.