The Whitaker Biomedical Engineering Institute, The Johns Hopkins University, Baltimore, MD 21218, USA. leixu@jhu.edu|The Whitaker Biomedical Engineering Institute, The Johns Hopkins University, Baltimore, MD 21218, USA. leixu@jhu.edu|The Whitaker Biomedical Engineering Institute, The Johns Hopkins University, Baltimore, MD 21218, USA. leixu@jhu.edu|The Whitaker Biomedical Engineering Institute, The Johns Hopkins University, Baltimore, MD 21218, USA. leixu@jhu.edu|The Whitaker Biomedical Engineering Institute, The Johns Hopkins University, Baltimore, MD 21218, USA. leixu@jhu.edu