Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9066, USA.|Bank of America Corporate Center, 100 North Tryon Street, Charlotte, NC, 28202, USA.|Broad Institute, 75 Ames Street, Cambridge, MA, 02142, USA.|Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9066, USA.|Institute for Computational Health Sciences, University of California San Francisco, Mission Hall, 550 16th Street, 4th Floor, Box 0110, San Francisco, CA, 94158, USA.|Department of Biological Sciences and The IRMACS Centre, Simon Fraser University, 8888 University Drive, Burnaby, V5A 1S6, British Columbia, Canada.|Department of Immunobiology, University of Arizona School of Medicine, 1656 E. Mabel Street, P.O. Box 245221, Tucson, AZ, 85724-5221, USA.|New Zealand eScience Infrastructure, University of Auckland, Level 10, 49 Symonds Street, Auckland, New Zealand.|Texas Advanced Computing Center, Research Office Complex 1.101, J.J. Pickle Research Campus, Building 196, 10100 Burnet Road (R8700), Austin, TX, 78758-4497, USA.|Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, 300 George Street, Suite 505, New Haven, CT, 06511, USA.|School of Biomedical Engineering, Science and Health Systems and Department of Microbiology and Immunology, College of Medicine, Drexel University, 3141 Chestnut Street, Philadelphia, PA, 19104, USA.|The IRMACS Centre (ASB 10905), Simon Fraser University, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.|School of Biomedical Engineering, Science and Health Systems, Drexel University, 3141 Chestnut Street, Philadelphia, PA, 19104, USA.|Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9036, USA.|Stanford University School of Medicine, 279 Campus Drive, Stanford, CA, 94305-5101, USA.|Texas Advanced Computing Center, Research Office Complex 1.101, J.J. Pickle Research Campus, Building 196, 10100 Burnet Road (R8700), Austin, TX, 78758-4497, USA.|Department of Molecular Biology and Biochemistry and Faculty of Health Sciences, Simon Fraser University, Blusson Hall, Room 11300, 8888 University Drive, Burnaby, BC, V5A 1S6, Canada.|Department of Pathology, Yale School of Medicine, 300 George Street, Suite 505, New Haven, CT, 06511, USA.|Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, 300 George Street, Suite 505, New Haven, CT, 06511, USA.|J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, CA, 92037, USA.|Department of Neurology and Neurotherapeutics, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9036, USA.|Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, 300 George Street, Suite 505, New Haven, CT, 06511, USA.|Department of Clinical Sciences, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390-9066, USA. lindsay.cowell@utsouthwestern.edu.