Algorithms|Alleles|Computational Biology|Computer Simulation|DNA Mutational Analysis|DNA, Viral|Disease Progression|Evolution, Molecular|HIV Core Protein p24|HIV Infections|HIV-1|HLA Antigens|Hepacivirus|Hepatitis C|Humans|Immune System|Normal Distribution|Phenotype|Principal Component Analysis|Protein Domains|Structure-Activity Relationship|nef Gene Products, Human Immunodeficiency Virus