Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA. roie@uw.edu.|Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA. rogan@uw.edu.|Department of Electrical Engineering & Computer Science, Center for Computational Biology, UC Berkeley, Berkeley, CA, 94720, USA. anat.kreimer@berkeley.edu.|Newe Yaar Research Center, Agricultural Research Organization, Ramat Yishay, 30095, Israel. shiri@agri.gov.il.|Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA. elbo@uw.edu.