Shanghai Institute of Medical Genetics, Shanghai Childrens Hospital, Shanghai Jiao Tong University, 24/1400 Beijing (W) Road, Shanghai 200040, Peoples Republic of China.|State Key Laboratory of Genetic Engineering Institute of Biostatistics, School of Life Science, Fudan University, Shanghai 200433, Peoples Republic of China.|Division of Biomedical Informatics, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH 45229, USA.|Institute for Systems Biology, Jianghan University, Wuhan, Hubei, Peoples Republic of China.|Shanghai Institute of Medical Genetics, Shanghai Childrens Hospital, Shanghai Jiao Tong University, 24/1400 Beijing (W) Road, Shanghai 200040, Peoples Republic of China, Department of Bioengineering (MC 063), University of Illinois at Chicago, Chicago, IL 60607-7052, USA and Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China.|Division of Biomedical Informatics, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH 45229, USA, Institute for Systems Biology, Jianghan University, Wuhan, Hubei, Peoples Republic of China.