Department of Statistics, University of California, Berkeley, CA, USA.|Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA.|Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.|Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.|Department of Statistics, University of Florida, Gainesville, FL, USA.|Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA.