Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA. ak5950@wayne.edu|Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA. ak5950@wayne.edu|Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA. ak5950@wayne.edu|Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA. ak5950@wayne.edu|Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA. ak5950@wayne.edu|Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, USA. ak5950@wayne.edu