Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Childrens Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA.|Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.|Division of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Childrens Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, PA, USA.