Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China. dpf05@mails.tsinghua.edu.cn <dpf05@mails.tsinghua.edu.cn>|Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, 100084, China. dpf05@mails.tsinghua.edu.cn <dpf05@mails.tsinghua.edu.cn>