Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr, 73, 14195 Berlin, Germany. zhike_zi@molgen.mpg.de|Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr, 73, 14195 Berlin, Germany. zhike_zi@molgen.mpg.de|Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr, 73, 14195 Berlin, Germany. zhike_zi@molgen.mpg.de|Computational Systems Biology, Max Planck Institute for Molecular Genetics, Ihnestr, 73, 14195 Berlin, Germany. zhike_zi@molgen.mpg.de