Institute of Bioinformatics and Structural Biology, National Tsing Hua University, 101, Section 2 Kuang Fu Road, Hsinchu 30013, Taiwan. b861636@life.nthu.edu.tw|Institute of Bioinformatics and Structural Biology, National Tsing Hua University, 101, Section 2 Kuang Fu Road, Hsinchu 30013, Taiwan. b861636@life.nthu.edu.tw|Institute of Bioinformatics and Structural Biology, National Tsing Hua University, 101, Section 2 Kuang Fu Road, Hsinchu 30013, Taiwan. b861636@life.nthu.edu.tw|Institute of Bioinformatics and Structural Biology, National Tsing Hua University, 101, Section 2 Kuang Fu Road, Hsinchu 30013, Taiwan. b861636@life.nthu.edu.tw