Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com|Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com|Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com|Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com|Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com|Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com|Johnson & Johnson Pharmaceutical Research & Development, Division of Janssen Pharmaceutica n.v., Beerse, Belgium. wtalloen@prdbe.jnj.com