School of Mathematics and Statistics, University of New South Wales, Sydney, Australia.|School of Mathematics and Statistics, University of New South Wales, Sydney, Australia.|Department of Clinical Pharmacology, Flinders University, Adelaide, Australia.|Kirby Institute, University of New South Wales, Sydney, Australia.|Faculty of Medicine, University of New South Wales, Sydney, Australia.|St Vincents Centre for Applied Medical Research, Darlinghurst, New South Wales, Sydney, Australia, Calimmune Pty Ltd, Darlinghurst, New South Wales, Australia.|School of Mathematics and Statistics, University of New South Wales, Sydney, Australia.