Biopolymer Design LLC, Acton, MA 01721, USA Engelhardt Institute of Molecular Biology, Moscow 119991, Russia.|Engelhardt Institute of Molecular Biology, Moscow 119991, Russia.|Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, 141701, Russia.|Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072 Australia.|Institute of Mathematical Problems of Biology, Pushchino, Moscow Region, 142290, Russia.|National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.|National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.