Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|Department of Neurology, Northwestern Brain Tumor Institute, Center for Genetic Medicine, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.|Department of Neurology, Northwestern Brain Tumor Institute, Center for Genetic Medicine, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America.|Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.|Pittsburgh Supercomputing Center, Pittsburgh, Pennsylvania, United States of America.|Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.