Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, MEM216, La Jolla, CA 92037, USA. koziol@scripps.edu|Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, MEM216, La Jolla, CA 92037, USA. koziol@scripps.edu