Department of Pathology, The Johns Hopkins University School of Medicine, Robert H and Clarice Smith Building, Room 4000C, 400 North Broadway, Baltimore, MD, 21287, USA. paul.aytton@gmail.com.|Department of Pathology, The Johns Hopkins University School of Medicine, Robert H and Clarice Smith Building, Room 4000C, 400 North Broadway, Baltimore, MD, 21287, USA. sthoma92@jhmi.edu.|Department of Pathology, The Johns Hopkins University School of Medicine, Robert H and Clarice Smith Building, Room 4000C, 400 North Broadway, Baltimore, MD, 21287, USA. zzhang7@jhmi.edu.|Department of Pathology, The Johns Hopkins University School of Medicine, Robert H and Clarice Smith Building, Room 4000C, 400 North Broadway, Baltimore, MD, 21287, USA. huizhang@jhu.edu.