Janssen Research & Development Ltd, High Wycombe, United Kingdom.|Janssen Research & Development LLC, United States of America.|Janssen Research & Development LLC, United States of America.|Janssen Research & Development LLC, United States of America.|National Heart and Lung Institute, Imperial College & Biomedical Research Unit, Royal Brompton & Harefield NHS Trust, London, United Kingdom.|National Heart and Lung Institute, Imperial College & Biomedical Research Unit, Royal Brompton & Harefield NHS Trust, London, United Kingdom.|Data Science Institute, Imperial College London, London, United Kingdom.|Janssen Research & Development LLC, United States of America.|Janssen Research & Development LLC, United States of America.