Physical Biosciences Division, Lawrence Berkeley National Laboratory, MS 972R525, Berkeley, CA 94720, USA, Information and Computational Sciences, The James Hutton Institute, Dundee DD2 5DA, UK, Bioinformatics Core, Harvard School of Public Health, Boston, MA 02115, USA, The Computational Biology Institute, George Washington University, Washington, DC 20052, USA, Bioinformatics Department, Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland and National Evolutionary Synthesis Center (NESCent), Durham, NC 27705, USA.|Physical Biosciences Division, Lawrence Berkeley National Laboratory, MS 972R525, Berkeley, CA 94720, USA, Information and Computational Sciences, The James Hutton Institute, Dundee DD2 5DA, UK, Bioinformatics Core, Harvard School of Public Health, Boston, MA 02115, USA, The Computational Biology Institute, George Washington University, Washington, DC 20052, USA, Bioinformatics Department, Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland and National Evolutionary Synthesis Center (NESCent), Durham, NC 27705, USA.|Physical Biosciences Division, Lawrence Berkeley National Laboratory, MS 972R525, Berkeley, CA 94720, USA, Information and Computational Sciences, The James Hutton Institute, Dundee DD2 5DA, UK, Bioinformatics Core, Harvard School of Public Health, Boston, MA 02115, USA, The Computational Biology Institute, George Washington University, Washington, DC 20052, USA, Bioinformatics Department, Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland and National Evolutionary Synthesis Center (NESCent), Durham, NC 27705, USA.|Physical Biosciences Division, Lawrence Berkeley National Laboratory, MS 972R525, Berkeley, CA 94720, USA, Information and Computational Sciences, The James Hutton Institute, Dundee DD2 5DA, UK, Bioinformatics Core, Harvard School of Public Health, Boston, MA 02115, USA, The Computational Biology Institute, George Washington University, Washington, DC 20052, USA, Bioinformatics Department, Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland and National Evolutionary Synthesis Center (NESCent), Durham, NC 27705, USA.|Physical Biosciences Division, Lawrence Berkeley National Laboratory, MS 972R525, Berkeley, CA 94720, USA, Information and Computational Sciences, The James Hutton Institute, Dundee DD2 5DA, UK, Bioinformatics Core, Harvard School of Public Health, Boston, MA 02115, USA, The Computational Biology Institute, George Washington University, Washington, DC 20052, USA, Bioinformatics Department, Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland and National Evolutionary Synthesis Center (NESCent), Durham, NC 27705, USA.|Physical Biosciences Division, Lawrence Berkeley National Laboratory, MS 972R525, Berkeley, CA 94720, USA, Information and Computational Sciences, The James Hutton Institute, Dundee DD2 5DA, UK, Bioinformatics Core, Harvard School of Public Health, Boston, MA 02115, USA, The Computational Biology Institute, George Washington University, Washington, DC 20052, USA, Bioinformatics Department, Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland and National Evolutionary Synthesis Center (NESCent), Durham, NC 27705, USA.