Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USA. sokolov@soe.ucsc.edu|Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USA. sokolov@soe.ucsc.edu|Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USA. sokolov@soe.ucsc.edu|Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USA. sokolov@soe.ucsc.edu|Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California 95064, USA. sokolov@soe.ucsc.edu