Department of Chemistry and Structural Biology, Institut Pasteur, UMR CNRS, Paris 3528, France.|Hub Bioinformatique Et Biostatistique, Institut Pasteur, C3bi, USR 3756 IP CNRS Paris 3528, France.|Department of Chemistry and Structural Biology, Institut Pasteur, UMR CNRS, Paris 3528, France.|Department of Chemistry and Structural Biology, Institut Pasteur, UMR CNRS, Paris 3528, France.|Department of Chemistry and Structural Biology, Institut Pasteur, UMR CNRS, Paris 3528, France.|Hub Bioinformatique Et Biostatistique, Institut Pasteur, C3bi, USR 3756 IP CNRS Paris 3528, France.|Department of Chemistry and Structural Biology, Institut Pasteur, UMR CNRS, Paris 3528, France.