Department of Pharmacology and Toxicology, University of Texas Medical Branch - Galveston, Galveston, TX, USA.|Department of Pharmacology and Toxicology, University of Texas Medical Branch - Galveston, Galveston, TX, USA.|Department of Pharmacology and Toxicology, University of Texas Medical Branch - Galveston, Galveston, TX, USA.|Department of Pharmacology and Toxicology, University of Texas Medical Branch - Galveston, Galveston, TX, USA.