Beckman Institute for Advanced Science and Technology, Department of Bioengineering, Department of Mechanical Science and Engineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering and University of Illinois Cancer Center, University of Illinois at Urbana-Champaign, 4265 Beckman Institute 405xc2xa0N. Mathews Avenue, Urbana, IL, 61801, USA. rxb@illinois.edu.