Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, St, Marys Campus, Norfolk Place London W2 1PG, UK. m.blangiardo@imperial.ac.uk|Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, St, Marys Campus, Norfolk Place London W2 1PG, UK. m.blangiardo@imperial.ac.uk|Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, St, Marys Campus, Norfolk Place London W2 1PG, UK. m.blangiardo@imperial.ac.uk