Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK. jonathan.cairns@cancer.org.uk|Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK. jonathan.cairns@cancer.org.uk|Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK. jonathan.cairns@cancer.org.uk|Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK. jonathan.cairns@cancer.org.uk|Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK. jonathan.cairns@cancer.org.uk|Department of Oncology, University of Cambridge, Li Ka Shing Centre, Cambridge, UK. jonathan.cairns@cancer.org.uk