Department of Biomedical Data Science, Dartmouth Geisel School of Medicine, Lebanon, NH 03756, USA.|Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA.|Department of Biomedical Data Science, Dartmouth Geisel School of Medicine, Lebanon, NH 03756, USA.|Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.|Division of Genetics and Epidemiology, Institute of Cancer Research, London SW7 3RP, UK.|Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA.|Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, FL 33612, USA.|Department of Biomedical Data Science, Dartmouth Geisel School of Medicine, Lebanon, NH 03756, USA.