The Jan and Dan Duncan Neurological Research Institute, Baylor College of Medicine, Houston, Texas, United States of America.|The Jan and Dan Duncan Neurological Research Institute, Baylor College of Medicine, Houston, Texas, United States of America.|The Jan and Dan Duncan Neurological Research Institute, Baylor College of Medicine, Houston, Texas, United States of America, Department of Computational and Applied Mathematics, Rice University, Houston, Texas, United States of America.