Ohio State University Biophysics Program, Department of Chemistry and Biochemistry, and Center for RNA Biology, The Ohio State University, Columbus, OH, USA Ohio State University Biophysics Program, Department of Chemistry and Biochemistry, and Center for RNA Biology, The Ohio State University, Columbus, OH, USA Ohio State University Biophysics Program, Department of Chemistry and Biochemistry, and Center for RNA Biology, The Ohio State University, Columbus, OH, USA.