Center for Biomolecular Science and Engineering, Jack Baskin School of Engineering, University of California, Santa Cruz, CA 95064, USA. cline@soe.ucsc.edu|Center for Biomolecular Science and Engineering, Jack Baskin School of Engineering, University of California, Santa Cruz, CA 95064, USA. cline@soe.ucsc.edu|Center for Biomolecular Science and Engineering, Jack Baskin School of Engineering, University of California, Santa Cruz, CA 95064, USA. cline@soe.ucsc.edu