Genomics and Disease Group, Bioinformatics and Genomics Programme, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology, Barcelona 08003, Spain, Universitat Pompeu Fabra (UPF), Barcelona 08003, Spain, IMIM, Hospital del Mar Medical Research Institute, Barcelona 08003, Spain, CIBER de Epidemiología y Salud Pública (CIBERESP), CRG, Instituto Carlos III Barcelona 08003, Spain.