Computing Applications and Research, Global Security Computing Applications Division, Lawrence Livermore National Security, Livermore, CA, 94550, USA. elo.leung@personalis.com.|Computing Applications and Research, Global Security Computing Applications Division, Lawrence Livermore National Security, Livermore, CA, 94550, USA. huang30@llnl.gov.|Computing Applications and Research, Global Security Computing Applications Division, Lawrence Livermore National Security, Livermore, CA, 94550, USA. eithon@capellabio.com.|Computing Applications and Research, Global Security Computing Applications Division, Lawrence Livermore National Security, Livermore, CA, 94550, USA. aldrin.montana@personalis.com.|Computing Applications and Research, Global Security Computing Applications Division, Lawrence Livermore National Security, Livermore, CA, 94550, USA. jan.v.soliman@gmail.com.|Computing Applications and Research, Global Security Computing Applications Division, Lawrence Livermore National Security, Livermore, CA, 94550, USA. zhou4@llnl.gov.