Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. wcchan@iis.sinica.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. wcchan@iis.sinica.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. wcchan@iis.sinica.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. wcchan@iis.sinica.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. wcchan@iis.sinica.edu.tw|Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. wcchan@iis.sinica.edu.tw