Department of Bioinformatics, GlaxoSmithKline, King of Prussia, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, GlaxoSmithKline, King of Prussia, PA, USA. barbara_eckman@sbphrd.com|Department of Bioinformatics, GlaxoSmithKline, King of Prussia, PA, USA. barbara_eckman@sbphrd.com