Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org|Research Center for Genetic Medicine, Childrens National Medical Center, 111 Michigan Avenue N.W., Washington, DC 20010, USA. rborup@cnmcresearch.org