Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu|Department of Medicine and Center for Human Genetics, Duke University Medical Center, Durham, North Carolina 27710, USA. yiju.li@duke.edu